Cardiac surgery in patients with essential thrombocytosis: a report of three cases

Yıl 2016, Cilt: 2 Sayı: 2, 147 - 150, 04.07.2016

Ufuk Aydin , Filiz Ata Derih Ay , Yusuf Ata Tamer Turk , Senol Yavuz

https://doi.org/10.18621/eurj.2016.5000183724

Öz

Essential thrombocytosis has been classified as a chronic myeloproliferative disorder. Patients with essential thrombocytosis undergoing cardiac surgery are at increased risk for bleeding and thrombosis. However, the incidence and treatment for this condition are not well known.  There are profound implications of essential thrombocytosis in patients undergoing cardiac surgery with the use of cardiopulmonary bypass, where heparin is used for anticoagulation. We want to present successful cardiac surgery in three patients with essential thrombocytosis. Patients received hydroxyurea and antiagregant treatment preoperatively and the thrombocyte counts were lowered to reference ranges. There were no cardiac or systemic complications due to essential thrombocytosis during the postoperative period.

Anahtar Kelimeler

Cardiopulmonary bypass, essential thrombocytosis, cardiac surgery

Kaynakça

• Scholzel BE, Endeman H, Dewilde W, Yilmaz A, de Weerdt O, ten Berg JM. Cardiac surgery in a patient with essential thrombocythemia: a case report. Neth Heart J 2010;18:378-380.
• Ahmed K, Vohra HA, Milne A, Langley SM. Aortic valve replacement in a young patient with essential thrombocytosis. J Cardiothorac Surg 2008;3:5.
• Gutierrez-Martin MA, Araji OA, Miranda N, Barquero JM. Mitroaortic valve replacement after aortic transapical approach failure in a patient with essential thrombocytosis. Interact Cardiovasc Thorac Surg 2010;11:360-361.
• Wang DW, Zhang Y, Yao JM, Xiao ZB. Surgical treatment of a ventricular aneurysm in a patient with essential thrombocythemia complicated by acute myocardial infarction: A case report. Exp Ther Med 2014;7:267-269.
• Briere JB. Essential thrombocythemia. Orphanet J Rare Dis 2007;2:3.
• Kaya K, Cavolli R, Telli A, Tasoz R. Off-pump coronary artery surgery in a patient with essential thrombocythaemia: two life-threatening complications in the same patient. BMJ Case Rep 2009;2009:bcr01.2009.1503.
• Hawkins JL, Myers GJ, Legare JF, Swyer W. Arterial filter bypass loop: what occurs in this area during cardiopulmonary bypass and are there potential patient implications. J Extra Corpor Technol 2010;42:71-74.
• Dogan A, Dogan AL, Canpinar H, Demirpence E. The Effect of hydroxyurea on the microbicidal functions of leukocyte. Turk J Biochem 2004;29:232-236.
• Czer LS, Bateman TM, Gray RJ, Raymond M, Stewart ME, Lee S, et al. Treatment of severe platelet dysfunction and hemorrhage after cardiopulmonary bypass: reduction in blood product usage with desmopressin. J Am Coll Cardiol 1987;9:1139-1147.