Evaluation of the effects on atherosclerosis and antioxidant and antimicrobial activities of Agaricus xanthodermus poisonous mushroom

Yıl 2020, Cilt: 6 Sayı: 6, 539 - 544, 04.11.2020

Betül Özaltun Mustafa Sevindik

https://doi.org/10.18621/eurj.524149

Cited By: 3

Öz

Objectives:
The aim of this study was to determine the total antioxidant capacity,
total oxidant capacity, oxidative stress index and antimicrobial activity of a
poisonous mushroom Agaricus xanthodermus.
The effects of mushrooms on atherosclerosis are due to their antioxidant
effects.

Methods: Mushroom samples collected from study field were extracted with methanol
(MeOH) and dichloromethane (DCM) using soxhlet apparatus. Total antioxidant
status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) were
measured using Rel Assay trade kits. Antimicrobial activities were tested on 9
microorganisms (Staphylococcus aureus,
S. aureus MRSA, Enterococcus faecalis, Escherichia
coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Candida albicans, C.krusei and C. glabrata)
using the modified agar dilution method.

Results: In this study A. xanthodermus has shown high
antioxidant and antimicrobial activities. In addition, the highest activities
of MeOH and DCM extracts of the mushrooms were demonstrated against E. coli, P. aeruginosa, and A. baumannii.

Conclusions: In conclusion, A. xanthodermus is considered to be a
poisonous mushroom and can be used as a pharmacological natural agent due to
its high antioxidant and antimicrobial activities.

Anahtar Kelimeler

Medicinal mushroom, poisonous mushrooms, Agaricus xanthodermus, antioxidant, antimicrobial, atherosclerosis

Kaynakça

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