Olgu Sunumu
BibTex RIS Kaynak Göster

Solitary myofibroma in children: a report of two cases

Yıl 2024, Cilt: 10 Sayı: 3, 333 - 337, 04.05.2024
https://doi.org/10.18621/eurj.1382704

Öz

Myofibromas are rare benign tumors of myofibroblasts, seen more commonly in children. These tumors typically involve soft tissues with a predilection for the head and neck. Malignant neoplasia is often suspected for these rapidly growing tumors in early childhood. Clinical and radiological findings are not typical, and histopathological examination makes the definitive diagnosis. This pathology requires the intervention of a multidisciplinary team and regular follow-up. We report our experience with two children with myofibromas, one in the right arm of a 5-year-old girl and the other in the right axilla of a 9-year-old boy. Tumors were totally resected in both children, who are under follow-up with no adjuvant treatment free of disease after surgery. Myofibroma should be considered in the differential diagnosis of pediatric soft tissue tumors. Surgical resection is sufficient for treatment and patients should be followed regularly for possible recurrences.

Etik Beyan

Since our study was a case report, no application was made for ethics committee approval. However, parents and patients were informed about the purpose of the case report and informed consent was obtained from both families for this publication.

Kaynakça

  • 1. Mahajan P, Hicks J, Chintagumpala M, Venkatramani R. Myofibroma in infancy and childhood. J Pediatr Hematol Oncol. 2017;39(3):e136-e139. doi: 10.1097/MPH.0000000000000732.
  • 2. Wu W, Chen J, Cao X, Yang M, Zhu J, Zhao G. Solitary infantile myofibromatosis in the bones of the upper extremities: Two rare cases and a review of the literature. Oncol Lett. 2013;6(5):1406-1408. doi: 10.3892/ol.2013.1584.
  • 3. Abujarir R, Salama H, Alsulaiti G, et al. Congenital scalp myofibroma: a case report. J Neonatal Perinat Med 2011;4(1):75-78.
  • 4. Choi JH, Ro JY. The 2020 WHO classification of tumors of soft tissue: selected changes and new entities. Adv Anat Pathol. 2021;28(1):44-58. doi: 10.1097/PAP.0000000000000284.
  • 5. Ogita A, Ansai SI. Infantile myofibroma: case report and review of the literature. J Nippon Med Sch. 2021;87(6):355-358. doi: 10.1272/jnms.JNMS.2020_87-609.
  • 6. Dhupar A, Carvalho K, Sawant P, Spadigam A, Syed S. Solitary intra-osseous myofibroma of the jaw: a case report and review of literature. Children (Basel). 2017;4(10):91. doi: 10.3390/children4100091.
  • 7. Oudijk L, den Bakker MA, Hop WC, et al. Solitary, multifocal and generalized myofibromas: clinicopathological and immunohistochemical features of 114 cases. Histopathology. 2012;60(6B):E1-11. doi: 10.1111/j.1365-2559.2012.04221.x.
  • 8. Oztürk O, Tutkun A. A case report of a malignant peripheral nerve sheath tumor of the oral cavity in neurofibromatosis type 1. Case Rep Otolaryngol. 2012;2012:936735. doi: 10.1155/2012/936735.
  • 9. Davies BM, du Plessis D, Gnanalingham KK. Myofibroma of the cervical spine presenting as brachialgia. J Neurosurg Spine. 2014;21(6):916-918. doi: 10.3171/2014.8.SPINE131194.
  • 10. Madhuri BK, Tripathy D, Mittal R. Solitary orbital myofibroma in a child: A rare case report with literature review. Indian J Ophthalmol. 2019;67(7):1240-1245. doi: 10.4103/ijo.IJO_1553_18.
Yıl 2024, Cilt: 10 Sayı: 3, 333 - 337, 04.05.2024
https://doi.org/10.18621/eurj.1382704

Öz

Kaynakça

  • 1. Mahajan P, Hicks J, Chintagumpala M, Venkatramani R. Myofibroma in infancy and childhood. J Pediatr Hematol Oncol. 2017;39(3):e136-e139. doi: 10.1097/MPH.0000000000000732.
  • 2. Wu W, Chen J, Cao X, Yang M, Zhu J, Zhao G. Solitary infantile myofibromatosis in the bones of the upper extremities: Two rare cases and a review of the literature. Oncol Lett. 2013;6(5):1406-1408. doi: 10.3892/ol.2013.1584.
  • 3. Abujarir R, Salama H, Alsulaiti G, et al. Congenital scalp myofibroma: a case report. J Neonatal Perinat Med 2011;4(1):75-78.
  • 4. Choi JH, Ro JY. The 2020 WHO classification of tumors of soft tissue: selected changes and new entities. Adv Anat Pathol. 2021;28(1):44-58. doi: 10.1097/PAP.0000000000000284.
  • 5. Ogita A, Ansai SI. Infantile myofibroma: case report and review of the literature. J Nippon Med Sch. 2021;87(6):355-358. doi: 10.1272/jnms.JNMS.2020_87-609.
  • 6. Dhupar A, Carvalho K, Sawant P, Spadigam A, Syed S. Solitary intra-osseous myofibroma of the jaw: a case report and review of literature. Children (Basel). 2017;4(10):91. doi: 10.3390/children4100091.
  • 7. Oudijk L, den Bakker MA, Hop WC, et al. Solitary, multifocal and generalized myofibromas: clinicopathological and immunohistochemical features of 114 cases. Histopathology. 2012;60(6B):E1-11. doi: 10.1111/j.1365-2559.2012.04221.x.
  • 8. Oztürk O, Tutkun A. A case report of a malignant peripheral nerve sheath tumor of the oral cavity in neurofibromatosis type 1. Case Rep Otolaryngol. 2012;2012:936735. doi: 10.1155/2012/936735.
  • 9. Davies BM, du Plessis D, Gnanalingham KK. Myofibroma of the cervical spine presenting as brachialgia. J Neurosurg Spine. 2014;21(6):916-918. doi: 10.3171/2014.8.SPINE131194.
  • 10. Madhuri BK, Tripathy D, Mittal R. Solitary orbital myofibroma in a child: A rare case report with literature review. Indian J Ophthalmol. 2019;67(7):1240-1245. doi: 10.4103/ijo.IJO_1553_18.
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Çocuk Hematolojisi ve Onkolojisi, Klinik Onkoloji
Bölüm Case Report
Yazarlar

Çağrı Coşkun 0000-0001-9725-8355

Kemal Kösemehmetoğlu 0000-0002-7747-0460

Mehmet Ayvaz 0000-0002-6471-127X

İbrahim Vargel 0000-0001-8723-1597

Üstün Aydıngöz 0000-0002-4325-847X

Hatice Nursun Özcan 0000-0003-4756-4359

Ali Varan 0000-0003-4911-1476

Bilgehan Yalçın 0000-0003-2840-0308

Erken Görünüm Tarihi 1 Ocak 2024
Yayımlanma Tarihi 4 Mayıs 2024
Gönderilme Tarihi 9 Kasım 2023
Kabul Tarihi 19 Aralık 2023
Yayımlandığı Sayı Yıl 2024 Cilt: 10 Sayı: 3

Kaynak Göster

AMA Coşkun Ç, Kösemehmetoğlu K, Ayvaz M, Vargel İ, Aydıngöz Ü, Özcan HN, Varan A, Yalçın B. Solitary myofibroma in children: a report of two cases. Eur Res J. Mayıs 2024;10(3):333-337. doi:10.18621/eurj.1382704

e-ISSN: 2149-3189 


The European Research Journal, hosted by Turkish JournalPark ACADEMIC, is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

by-nc-nd.png

2024