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Yıl 2021, , 77 - 88, 30.06.2021
https://doi.org/10.35864/evmd.674349

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Microbiota refers to bacteria, viruses, fungi and archaea which are found in vital systems such as the gastrointestinal system, skin, respiratory system and urogenital system. The genome of the microbiota contains 1000 times more gene sequences than the organism genome. Microbiota has effects on energy metabolism, hepatic functions, immune system development, motor system and endocrine functions. Microbiota composition can break down by diet, use of antibiotics, stress, etc., and the disruption of this balance on microbiota is called “dysbiosis”. In 2007, the Human Microbiology Project activity, which will shed light on further research, has been carried out and has great importance in determining the character of human microbiota. The studies on microbiota of farm animal and pets are unprecedented yet. Microbiota has a crucial role in increasing the milk yield in order to increase the yield characteristics of farm animals and to maximize the utilization of feed. Pets, especially dogs, have been accompanied by humans since the early ages and share both the habitat and the microbiota with humans. It has been proven that the presence of the pet has a major role in the development of microbiota, both for adults and especially for newborn children, and reduces the incidence of allergic diseases such as asthma, allergic rhinitis, atopic dermatitis. Microbiota studies in veterinary medicine are relatively new and there is still many issues to be investigated.

Kaynakça

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Veteriner Sahada Güncel Mikrobiyota Kavramı

Yıl 2021, , 77 - 88, 30.06.2021
https://doi.org/10.35864/evmd.674349

Öz

Mikrobiyota; canlı vücudunda başlıca, gastrointestinal sistem, deri, solunum sistemi, ürogenital sistem gibi hayati sistemlerde bulunan, bakteri, virus, mantar ve arkeleri ifade eder. Mikrobiyotanın genomu, canlı genomundan 1000 kat daha fazla gen dizilimi içerir. Mikrobiyotanın vücutta enerji metabolizması, hepatik fonksiyonlar, immün sistem gelişimi, motor sistem ve endokrin fonksiyonları üzerine etkileri vardır. Mikrobiyota kompozisyonu; diyet, antibiyotik kullanımı, stres gibi faktörlerden dolayı bozulabilmektedir ve mikrobiyotanın bu dengesinin bozulmasına “disbiyozis” denir. 2007 yılında daha sonraki araştırmalara ışık tutacak olan İnsan Mikrobiyom Projesi faaliyete geçirilmiş ve insan mikrobiyotasının özelliklerinin belirlenmesinde büyük önem taşımıştır. Çiftlik ve pet hayvanlarında yapılan çalışmalar henüz yenidir. Çiftlik hayvanlarında verim özelliklerinin artmasında, yemden yararlanmanın maksimum düzeyde tutulabilmesinde, süt yağının artışında mikrobiyotanın çok önemli bir rolü vardır. Pet hayvanlar, özellikle de köpekler ilk çağlardan beri insanoğluna eşlik edip, insanlarla hem yaşam alanını hem de mikrobiyotasını paylaşmaktadır. Evcil hayvan varlığının hem yetişkinler için, hem de özellikle yeni doğan çocukların mikrobiyota gelişiminde büyük bir rolü olduğu ve astım, alerjik rinit, atopik dermatit gibi alerjik hastalıkların görülme oranını azalttığı kanıtlanmıştır. Veteriner sahada mikrobiyota çalışmaları dünyada henüz son yıllarda çalışılmaya başlanmış olup, gün geçtikçe daha fazla araştırma yapılmaktadır ve hala araştırılmayı bekleyen birçok konu bulunmaktadır.

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  • Strachan DP. (1989) Hay fever, hygiene, and household size. BMJ. 299,1259-1260. doi:10.1136/bmj.299.6710.1259
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  • Suchodolski JS, Camacho J, Steiner JM. (2008) Analysis of bacterial diversity in the canine duodenum, jejunum, ileum, and colon by comparative 16S rRNA gene analysis. FEMS Microbiol Ecol. 66, 567–578. doi:10.1111/j.1574-6941.2008.00521.x
  • Suchodolski JS, Dowd SE, Westermarck E, Steiner JM, Wolcott RD, Spillmann T, Harmoinen JA. (2009) The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. BMC Microbiol. 9, 210. doi: 10.1186/1471-2180-9-210.
  • Suchodolski JS, Olson E, Honneffer JB, Guard B, Blake A, AlShawaqfeh M, Steiner JM, Barr J, Gaschen F. (2016) Effects of a hydrolyzed protein diet and metronidazole on the fecal microbiome and metabolome in healthy dogs. J Vet Intern Med 30, 1455.
  • Suchodolski JS. (2011) Companion animals symposium: microbes and gastrointestinal health of dogs and cats. J Anim Sci. 89, 1520–1530. doi: 10.2527/jas.2010-3377
  • Summers SC, Quimby JM, Isaiah A, Suchodolski JS, Lunghofer PJ, Gustafson DL. (2019) The fecal microbiome and serum concentrations of indoxyl sulfate and p-cresol sulfate in cats with chronic kidney disease. J Vet Intern Med. 33, 662-669. doi:10.1111/jvim.15389
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  • Yegani M, Korver DR. (2008) Factors affecting intestinal health in poultry. Poult Sci. 87, 2052–2063. doi: 10.3382/ps.2008-00091
  • Yeoman CJ, Chia N, Jeraldo P, Sipos M, Goldenfeld ND, White BA. (2012) The microbiome of the chicken gastrointestinal tract. Anim Health Res Rev. 13, 89–99. doi: 10.1017/S1466252312000138
  • Zitvogel L, Daillere R, Roberti MP, Routy B, Kroemer G. (2017) Anticancer effects of the microbiome and its products. Nat Rev Microbiol. 15, 465–478. doi: 10.1038/nrmicro.2017.4400556.x
Toplam 114 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Veteriner Bilimleri, Veteriner Cerrahi
Bölüm Derleme
Yazarlar

Emre Küllük

Duygu Dalgın

Yayımlanma Tarihi 30 Haziran 2021
Gönderilme Tarihi 13 Ocak 2020
Yayımlandığı Sayı Yıl 2021

Kaynak Göster

APA Küllük, E., & Dalgın, D. (2021). Veteriner Sahada Güncel Mikrobiyota Kavramı. Etlik Veteriner Mikrobiyoloji Dergisi, 32(1), 77-88. https://doi.org/10.35864/evmd.674349


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