Bir organize sütçü işletmede Bovine Partainfluenza 3 Virus enfeksiyonunun prekolostral olarak serolojik değerlendirmesi.

Yıl 2020, Cilt: 31 Sayı: 1, 1 - 6, 07.06.2020

Sibel Gür , Ayşe Gencay Göksu Fatih Mehmet Birdane

https://doi.org/10.35864/evmd.631045

Öz

Danalar anneden yavruya immunoglobulin geçişini
önleyen syndesmochorial plasenta yapısı nedeniyle agamaglobulinemik olarak
doğarlar. Prekolostral antikor varlığı direkt olarak in-utero enfeksiyonu
gösterir. Bu çalışmada prekolostral danalar ve annelerinde Bovine Parainfluenza
3 virus (BPI3V) enfeksiyonunu araştırmak amaçlanmıştır. Örnekler yaklaşık on
yıl once kurulmuş büyük ölçekli bir çiftlikten elde edildi. Kan serum örnekleri
yaklaşık 3 ay süresince, doğumdan hemen sonra prokolostral danalardan (n=123)
ve annelerinden alındı. Kan serum örnekleri referens suş SF-4 kullanılarak
yapılan Serum Nötralizasyon ile test edildi. BPI3V spesifik antikorlar 123
annenin 119’unda (%96.7) tespit edildi ve antikor titrelerinin düzenli çan
eğrisi gösterdiği ve 1/20 ile 1/40 aralığında pik yaptığı belirlendi.
Prekolostral danalrın ise 31’inde (%25.2) 1/5 ile 1/80 aralığında antikor
titreleri belirlendi. Antikor pozitif danaların annelerinin ise beklendiği gibi
yakın zamanda geçirilmiş enfeksiyona bağlı olarak daha yüksek olduğu görüldü.
Elde edilen verilere göre nerdeyse tüm ineklerin BPI3V’a maruz kaldığı ve her dört
gebe ineğin birinin transplasental enfeksiyon geçirdiği anlaşıldı. Geçerli
Veteriner uygulamalarının temeli, özellikle sütçü intensif yetiştiricilik
açısından önemli olan koruyucu hekimliğe dayanır. Prekolostral antikor
kontrolleri yakın gelecekte karşılaşılabilecek postpartum enfeksiyonları tahmin
ve elimine etmek için kullanılabilecek yararlı yöntem olarak kullanılabilir. 

Anahtar Kelimeler

Bovine Parainfluenza Virus 3, Prekolostral, Serokontrol, Sığır

Serological evaluation of precolostral Bovine Parainfluenza 3 Virus infection in an organised dairy herd

Öz

Calves are born agamaglobulinemic due to
syndesmochorial placenta features that prevent immunoglobulin transfer to the
foetus from the dam. The presence of precolostral antibody (ab) directly
induces in-utero infection. The purpose of this study was to investigate Bovine
Parainfluenza 3 virus (BPI3V) infection in precolostral calves and their dams. Samples were obtained from large-scale
dairy cattle farm, which was established nearly 10 years ago. Blood serum
samples were collected immediately after birth from precolostral calves (n=123)
and their dams for about three-month period. Blood serum samples tested with
Serum Neutralisation test using reference strain SF-4. BPI3V specific ab was
found in 119 of 123 dams (96.7%), and ab titres showed a regular bell curve
distribution’s and peak points were at 1/20 and 1/40 interval. Out of all
precolostral calves, 31 (25.2%) were ab positive between 1/5 and 1/80 titer
values. Average ab titre level was higher in the dams of ab positive calves as
expected a result of recent infection history. The obtained data revealed that almost all the adults were exposed
to BPI3V and one of the four pregnant had transplacental infections. Current
veterinary practices are based on the prevention of diseases, which is an
important point for intensive dairy breeding enterprises. Precolostral ab controls
can be used as a convenient tool for estimating and eliminating the risks of
upcoming postpartum infections.

Anahtar Kelimeler

Bovine Parainfluenza Virus 3, Cattle, Precolostral, Serocontrol

Kaynakça

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