Scabies Treatment in Turkey and Plants Traditionally Used in the Treatment

Yıl 2024, , 423 - 438, 26.08.2024

Dicle Naz Toktaş , Gülay Melikoğlu , Aynur Sarı

https://doi.org/10.56061/fbujohs.1268325

Öz

Scabies, which is an itchy skin disease that has increased especially recently in our country, is defined as a disease caused by Sarcoptes scabiei var. hominis acar in humans. Scabies can be transmitted from person to person and is characterized by itching and a rash that worsens at night. While topical preparations containing permethrin and sulfur are actively used in treatment, magisterial drugs prepared in pharmacies have begun to take their place. The fact that acars are becoming more and more resistant to the current active substances used in treatment reveals the need for the development of new acaricidal drug substances. The existence of significant differences in terms of efficacy and safety profile in studies comparing existing insecticide drugs and herbal drugs paves the way for investigating the use of natural origin substances in disease. In this article, the current active substances and natural ingredients used in the treatment of scabies were examined, the literature of the plants used in the treatment of scabies among the local people in our country was searched, and a table containing the substances they contain and their forms of use was created. The plants in the table mainly belong to the Cupressaceae, Liliaceae and Pinaceae families, and the roots, aerial parts and tar obtained from the plant are used in the treatment. Conducting activity studies with plants containing natural compounds, which are used in scabies among the local people and have proven to show acaricidal activity, may allow the evaluation of new options in treatment.

Anahtar Kelimeler

acaricides, essential oil, medicinal plant, sarcoptes scabiei, scabies

Türkiye’de Uyuz Tedavisi ve Tedavide Geleneksel Olarak Kullanılan Bitkiler

Öz

Ülkemizde özellikle son dönemde artan kaşıntılı bir deri hastalığı olan uyuz, Sarcoptes scabiei var. hominis akarının insanda yol açtığı bir hastalık olarak tanımlanmaktadır. Gece şiddetlenen kaşıntı ve döküntü ile karakterize olan uyuz hastalığı, insandan insana bulaşarak ilerlemektedir. Tedavide aktif olarak permetrin ve kükürt içeren topikal preparatlar kullanılırken eczanelerde hazırlanan majistral ilaçlarda tedavide yerini almaya başlamıştır. Akarların tedavide kullanılan mevcut etken maddelere karşı giderek daha dirençli hale gelmesi, yeni akarisid ilaç maddelerinin geliştirilmesi ihtiyacını ortaya koymaktadır. Mevcut insektisid ilaçlar ile bitkisel ilaçların karşılaştırıldığı çalışmalarda etkinlik ve güvenlik profili açısından anlamlı farkların olması doğal kaynaklı maddelerin hastalıkta kullanımının araştırılmasının önünü açmaktadır. Bu makalede uyuz tedavisinde kullanılan mevcut etken maddeler ve doğal içerikler incelenmiş, ülkemizde halk arasında uyuz tedavisinde kullanımı olan bitkilerin literatür taraması yapılarak içeriklerinde bulundurdukları maddeler ve kullanım şekillerini içeren tablo oluşturulmuştur. Tabloda yer alan bitkiler ağırlıklı olarak Cupressaceae, Liliaceae ve Pinaceae familyalarına ait olup tedavide kökler, toprak üstü kısımlar ve yine bitkiden elde edilen katranlar kullanılmaktadır. Halk arasında uyuzda kullanımı olup özellikle akarisidal aktivite gösterdiği kanıtlanan doğal bileşikleri içeren bitkilerle aktivite çalışması yapılması tedavide yeni seçeneklerin değerlendirilmesine olanak sağlayabilir.

Anahtar Kelimeler

akarisidler, sarcoptes scabiei, tıbbi bitki, uçucu yağ, uyuz

Kaynakça

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