The Critical Role of Estrogen in Menopausal Osteoporosis

Yıl 2017, Cilt: 7 Sayı: 4, 418 - 427, 14.11.2017

Mrinali Sharma Sathees Chandra

https://doi.org/10.16899/gopctd.315052

Öz

Osteoporosis is a bone disorder, which causes a reduction in the mass and density of bone tissue, and implants a greater possibility for skeletal fractures to occur. This bone disease is especially relevant for women suffering from menopause. Due to this general prevalence, osteoporosis requires continual intervention in the pharmacological and medicinal industry for better treatment alternatives for patients. A focal point for many scientific research studies for osteoporosis has been estrogen. As a hormone, estrogen exhibits a fluctuating capacity in the woman's body, and this has been proclaimed to be a qualifying explanation as to why women develop osteoporosis after menopause.
The purpose of this paper is to interpret estrogen's capacity to treat menopausal osteoporosis. Thus, in this article, estrogen’s significance in bone health and different forms, derivatives, and the combinations of estrogen is examined in terms of efficiency in treating osteoporosis.

Anahtar Kelimeler

osteoporosis, menopause, estrogen, bone, fractures

Menapoz Osteoporozunda Östrojenin Kritik Rolü

Öz

Osteoporoz, kemik dokusunun kütlesinde ve yoğunluğunda azalmaya neden olan ve iskelet kırıklarının ortaya çıkma ihtimalini artıran bir kemik bozukluğudur. Bu kemik hastalığı, menopozdaki kadınlar için özellikle önemlidir. Bu genel prevalansa bağlı olarak osteoporoz hastaları için, farmakolojik ve tıbbi endüstride daha iyi tedavi seçenekleri için sürekli girişim gerektirir. Osteoporoz için birçok bilimsel araştırma çalışmasının odak noktası, östrojen olmuştur. Bir hormon olarak, östrojen kadının vücudunda değişken bir kapasite sergiler ve kadınların neden menopozdan sonra osteoporoz geliştiğine ilişkin elverişli bir açıklama olduğu şeklinde suçlanıyor. 

Bu yazının amacı, östrojenin menopoz osteoporozu tedavi etme kapasitesini yorumlamaktır. Bu nedenle, bu makalede, östrojenin kemik sağlığında, farklı şekillerde, türevlerde ve östrojen kombinasyonlarında osteoporoz tedavisinde etkinlik açısından önemi, incelenmektedir.

Anahtar Kelimeler

osteoporoz, menopoz, östrojen, kemik, kırıklar

Kaynakça

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