Evaluation of Patient Follow-up with Transient Hypogammaglobulinemia in Infancy Diagnosis

Yıl 2019, Cilt: 9 Sayı: 1, 15 - 20, 27.03.2019

Alaaddin Yorulmaz , Hasibe Artaç , İsmail Reisli

https://doi.org/10.16899/gopctd.534014

Cited By: 1

Öz

Introduction: In this study, we aimed to investigate the clinical, laboratory and
demographic characteristics of patients with THI who were admitted with the
suspicion of recurrent infection and immunodeficiency.

Methods: The study included 287 patients who
were followed up with the diagnosis of transient hypogammaglobulinemia in
infancy at Selçuk University Meram Faculty of Medicine, Child Health and
Diseases Department and Department of Pediatric Allergy and Immunology, between
November 2001 and November 2006. The age, gender, the age of the complaints and
diagnosis, clinical features, family history and laboratory findings of the
patients were examined. The data of the patients were collected by using the
hospital file and the records in the Pediatric Immunology cards.

Results: 195 (67.9%) of the patients were male and 92 (32.1%) were
female (p <0.05). The M/F ratio was 2.1. The age of diagnosis ranged from 8
months to 48 months with a mean of 24.6±11.3 months. The duration between the
complaints and the age of diagnosis was between 1 and 63 months and the mean
age was 13.5±8.6 months. Complaints of the patients were recurrent upper
respiratory tract infection (URTI) 54.35% (n:156), lower respiratory tract
infection (LRTI) 50.52% (n:145), sinusitis 41.26% (n:118), recurrent otitis,
28.22% (n:81), asthma finding 12.89% (n=37), allergic skin and rhinitis
findings 10.45% (n:30), gastroenteritis 6.96% (n:20), urinary tract infection
4.18% (n:12), and moniliazis was 3.83% (n:11).

Conclusion: THI is usually a self-recovering disease around three years
of age. In order to prevent complications such as chronic lung disease and to
reduce morbidity, it is important to follow up the cases regularly.

Anahtar Kelimeler

Transient hypogammaglobunemia, immunodeficiency

Kaynakça

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