Pediatrik COVID-19 Enfeksiyonu ve Hemşirelik Yaklaşımı: Güncel Gelişmeler

Yıl 2022, Cilt: 5 Sayı: 2, 124 - 137, 18.07.2022

Esra Ekmekci , Güzide Özden Akcan Didem Kurap Öcebe Rabiye Güney , Esra Sevketoglu

https://doi.org/10.54189/hbd.975030

Öz

ÖZET
Yeni Koronavirüs Hastalığı 2019 yılı sonunda ortaya çıkmış ve kısa sürede tüm dünyayı etkisi altına alarak küresel bir pandemiye dönüşmüştür. Pandeminin başlangıcında her yaştan insanı etkileyen bu enfeksiyonun çocuklarda yetişkinlere göre çok hafif seyrettiği bildirilmiştir. Ancak son yapılan araştırmalarda, multisistem enflamatuar sendromu ile daha ağır seyreden tabloların da olduğu görülmüştür. Hastalığın şiddeti pediatrik grupta özellikle bir yaş altında daha fazladır. Buna karşın pediatrik vakalarda hastalığın tedavisine yaklaşım hala belirsizliğini korumaktadır. Çocuklara uygulanan farmakolojik tedaviler yetişkin çalışmalarına dayandırılmaktadır. Semptomlara yönelik uygun hemşirelik bakımının iyileşmede önemli bir yeri vardır. İmmünsuprese çocukların koronavirüs hastalığı için risk altında olduğu ve hastalığı daha şiddetli geçireceği öngörülmektedir. İmmünsuprese ilaç tedavisi alan ya da transplantasyon yapılmış çocukların rutin olarak Yeni Koronavirüs Hastalığı testi yaptırması önerilmektedir. Hastalıktan korunmada çocuklarda yetişkinlerden daha hafif geçirilmesine rağmen akut enfeksiyonu takiben multisistem enflamatuar sendrom gelişebilmesi ve altta yatan tıbbi sorunları olan çocuklarda ciddi hastalık riski nedeniyle aşılanma önemlidir. Okul çağındaki çocuklar arasında hastalık bulaşma riskinin azaltılması ve korunmanın sağlanmasında okul hemşirelerinin süreci etkin bir şekilde yönetmeleri son derece önemlidir. Bu derlemede, çocuklarda Yeni Koronavirüs Hastalığı’nın etiyolojisi, belirti ve bulguları, tedavisi, hemşirelik bakımı ve korunma yolları konusunda güncel bilgilerin verilmesi amaçlanmıştır.

Anahtar Kelimeler

COVID-19, Çocuk Bakımı, Hemşirelik Bakımı

Destekleyen Kurum

Yok

Proje Numarası

Yok

Teşekkür

Yok

Kaynakça

• Alhazzani, W., Møller, M. H., Arabi, Y. M., Loeb, M., Gong, M. N., Fan, E., Oczkowski, S., Levy, M. M., Derde, L., Dzierba, A., Du, B., Aboodi, M., Wunsch, H., Cecconi, M., Koh, Y., Chertow, D. S., Maitland, K., Alshamsi, F., Belley-Cote, E., Greco, M., … Rhodes, A. (2020). Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19). Critical Care Medicine, 48(6), e440–e469.doi: 10.1007/s00134-020-06022-5.
• American Academy of Pediatrics(AAP)(2021a). Children and COVID-19: State Level Data Report. Erişim linki: https://services.aap.org/en/pages/2019-novel-coronavirus-COVID-19-infections/children-and-COVID-19-state-level-data-report/
• American Academy of Pediatrics. (1997). Breastfeeding and the use of human milk. Work Group on Breastfeeding. Pediatrics,100(6), 1035-9. doi: 10.1542/peds.100.6.1035.
• American Academy of Pediatrics (AAP). (2021b). COVID-19 Guidance for Safe Schools. Erişim linki: https://services.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/clinical-guidance/covid-19-planning-considerations-return-to-in-person-education-in-schools/
• Anderson, E. J., Campbell, J. D., Creech, C. B., Frenck, R., Kamidani, S., Munoz, F. M., Nachman, S., & Spearman, P. (2021). Warp Speed for Coronavirus Disease 2019 (COVID-19) Vaccines: Why Are Children Stuck in Neutral?. Clinical İnfectious Diseases: An Official Publication of the Infectious Diseases Society of America, 73(2), 336–340.doi: 10.1093/cid/ciaa1425.
• Balashov, D., Trakhtman, P., Livshits, A., Kovalenko, I., Tereshenko, G., Solopova, G., Petraikina, E., Maschan, A., & Novichkova, G. (2021). SARS-CoV-2 convalescent plasma therapy in pediatric patient after hematopoietic stem cell transplantation. Transfusion and apheresis science: official journal of the World Apheresis Association: Official Journal of the European Society for Haemapheresis, 60(1), 102983.doi: 10.1016/j.transci.2020.102983.
• Bixler, D., Miller, A. D., Mattison, C. P., Taylor, B., Komatsu, K., Peterson Pompa, X., Moon, S., Karmarkar, E., Liu, C. Y., Openshaw, J. J., Plotzker, R. E., Rosen, H. E., Alden, N., Kawasaki, B., Siniscalchi, A., Leapley, A., Drenzek, C., Tobin-D'Angelo, M., Kauerauf, J., Reid, H., … Pediatric Mortality Investigation Team (2020). SARS-CoV-2-Associated Deaths Among Persons Aged <21 Years - United States, February 12-July 31, 2020. MMWR. Morbidity and mortality weekly report, 69(37), 1324–1329.doi: 10.15585/mmwr.mm6937e4.
• Burke, R. M., Killerby, M. E., Newton, S., Ashworth, C. E., Berns, A. L., Brennan, S., Bressler, J. M., Bye, E., Crawford, R., Harduar Morano, L., Lewis, N. M., Markus, T. M., Read, J. S., Rissman, T., Taylor, J., Tate, J. E., Midgley, C. M., & Case Investigation Form Working Group (2020). Symptom Profiles of a Convenience Sample of Patients with COVID-19- United States, January-April 2020. MMWR. Morbidity and mortality weekly report, 69(28), 904–908.doi: 10.15585/mmwr.mm6928a2.
• Carlotti, A., Carvalho, W. B., Johnston, C., Rodriguez, I. S., & Delgado, A. F. (2020). COVID-19 Diagnostic and Management Protocol for Pediatric Patients. Clinics (Sao Paulo, Brazil), 75, e1894. doi: 10.6061/clinics/2020/e1894..
• Centers for Disease Control and Prevention(CDC) (2020a). Multisystem Infammatory Syndrome in Children (MIS-C) Associated with Coronavirus Disease 2019 (COVID-19). Erişim linki: https://emergency.cdc.gov/han/2020/han00432.asp
• Centers for Disease Control and Prevention (CDC). (2020b). Coronavirüs disease (COVID-19) and breastfeeding. Erişim linki: https://www.cdc.gov/breastfeeding/breastfeeding-special-circumstances/maternal-or-infant-illnesses/COVID-19-and-breastfeeding.html
• Centers for Disease Control and Prevention (CDC). (2021). Hospitalization of adolescents aged 12–17 years with laboratory-confirmed COVID-19 — COVID-NET, 14 States, March 1, 2020–April 24, 2021. Erişim linki: https://www.cdc.gov/mmwr/volumes/70/wr/pdfs/mm7023e1-H.pdf
• Centers for Disease Control and Prevention (CDC). (2020c). COVID-19 Vaccines for children and teens. Erişim linki: https://www.cdc.gov/coronavirus/2019-ncov/downloads/vaccines/toolkits/COVID-19-Vaccine-for-Preteens_Teens-508.pdf
• Chen, H., Guo, J., Wang, C., Luo, F., Yu, X., Zhang, W., Li, J., Zhao, D., Xu, D., Gong, Q., Liao, J., Yang, H., Hou, W., & Zhang, Y. (2020). Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet (London, England), 395(10226), 809–815.doi: 10.1016/S0140-6736(20)30360-3.
• Chiotos, K., Hayes, M., Kimberlin, D. W., Jones, S. B., James, S. H., Pinninti, S. G., Yarbrough, A., Abzug, M. J., MacBrayne, C. E., Soma, V. L., Dulek, D. E., Vora, S. B., Waghmare, A., Wolf, J., Olivero, R., Grapentine, S., Wattier, R. L., Bio, L., Cross, S. J., Dillman, N. O., … Nakamura, M. M. (2021). Multicenter Interim Guidance on Use of Antivirals for Children With Coronavirus Disease 2019/Severe Acute Respiratory Syndrome Coronavirus 2. Journal of the Pediatric Infectious Diseases Society, 10(1), 34–48. doi: 10.1093/jpids/piaa115.
• Choi, S. H., Kim, H. W., Kang, J. M., Kim, D. H., & Cho, E. Y. (2020). Epidemiology and clinical features of coronavirus disease 2019 in children. Clinical and Experimental Pediatrics, 63(4), 125–132. doi: 10.3345/cep.2020.00535.
• Dalton, L., Rapa, E., & Stein, A. (2020). Protecting the psychological health of children through effective communication about COVID-19. The Lancet. Child & Adolescent Health, 4(5), 346–347. doi: 10.1016/S2352-4642(20)30097-3.
• Deville, E., Song, E. & Ouelette, C.P. (2021a). Coronavirus disease 2019 (COVID-19): Clinical manifestations and diagnosis in children. In: Edwards MS, editors. UpToDate.2021.
• Deville, E., Song, E. & Ouelette, C. P. (2021b). Coronavirus disease 2019 (COVID-19): Management in children. In: Edwards MS, editors. UpToDate.2021.
• Di Giorgio, E., Di Riso, D., Mioni, G., & Cellini, N. (2020). The interplay between mothers' and children behavioral and psychological factors during COVID-19: an Italian study. European Child & Adolescent Psychiatry, 1–12. Advance online publication. doi: 10.1007/s00787-020-01631-3.
• Diao, B., Wang, C., Tan, Y., Chen, X., Liu, Y., Ning, L., Chen, L., Li, M., Liu, Y., Wang, G., Yuan, Z., Feng, Z., Zhang, Y., Wu, Y., & Chen, Y. (2020). Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19). Frontiers in immunology, 11, 827.doi: 10.3389/fimmu.2020.00827.
• Diorio, C., Anderson, E. M., McNerney, K. O., Goodwin, E. C., Chase, J. C., Bolton, M. J., Arevalo, C. P., Weirick, M. E., Gouma, S., Vella, L. A., Henrickson, S. E., Chiotos, K., Fitzgerald, J. C., Kilbaugh, T. J., John, A., Blatz, A. M., Lambert, M. P., Sullivan, K. E., Tartaglione, M. R., Zambrano, D., … Teachey, D. T. (2020). Convalescent plasma for pediatric patients with SARS-CoV-2-associated acute respiratory distress syndrome. Pediatric Blood & Cancer, 67(11), e28693. doi: 10.1002/pbc.28693.
• Fanta, C.H. (2021). An overview of asthma management. In: Wood RA, Bochner BS, editors. UpToDate.2021.
• Farshi, R.M., Jabraeili, M., Moharrami, N., & Malakouti, J. (2020). Nursing care in a child with coronavirus disease 2019: A case study. Hormozgan Med J., 24(4),1-5. doi: 10.5812/hmj.108040
• Feldman, A. G., Adams, M. A., Wachs, M. E., Abzug, M. J., Pratscher, L., Jackson, W. E., Pomfret, E. A., & Sundaram, S. S. (2020). Successful non-directed living liver donor transplant for an infant with biliary atresia during the COVID-19 pandemic. Pediatric Transplantation, 24(8), e13816.doi: 10.1111/petr.13816.
• Goldenberg, N. A., Sochet, A., Albisetti, M., Biss, T., Bonduel, M., Jaffray, J., MacLaren, G., Monagle, P., O'Brien, S., Raffini, L., Revel-Vilk, S., Sirachainan, N., Williams, S., Zia, A., Male, C., & Pediatric/Neonatal Hemostasis and Thrombosis Subcommittee of the ISTH SSC (2020). Consensus-based clinical recommendations and research priorities for anticoagulant thromboprophylaxis in children hospitalized for COVID-19-related illness. Journal of thrombosis and haemostasis : JTH, 18(11), 3099–3105.doi: 10.1111/jth.15073.
• Heinz, N., Griesemer, A., Kinney, J., Vittorio, J., Lagana, S. M., Goldner, D., Velasco, M., Kato, T., Lobritto, S., & Martinez, M. (2020). A case of an Infant with SARS-CoV-2 hepatitis early after liver transplantation. Pediatric Transplantation, 24(8), e13778.doi: 10.1111/petr.13778.
• Henderson, L. A., Canna, S. W., Friedman, K. G., Gorelik, M., Lapidus, S. K., Bassiri, H., Behrens, E. M., Ferris, A., Kernan, K. F., Schulert, G. S., Seo, P., Son, M., Tremoulet, A. H., Yeung, R., Mudano, A. S., Turner, A. S., Karp, D. R., & Mehta, J. J. (2021). American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 2. Arthritis & rheumatology (Hoboken, N.J.), 73(4), e13–e29. doi: 10.1002/art.41616.
• Hoang, A., Chorath, K., Moreira, A., Evans, M., Burmeister-Morton, F., Burmeister, F., Naqvi, R., Petershack, M., & Moreira, A. (2020). COVID-19 in 7780 pediatric patients: A systematic review. EClinicalMedicine, 24, 100433. doi: 10.1016/j.eclinm.2020.100433.
• Jarmoliński, T., Matkowska-Kocjan, A., Rosa, M., Olejnik, I., Gorczyńska, E., Kałwak, K., & Ussowicz, M. (2021). SARS-CoV-2 viral clearance during bone marrow aplasia after allogeneic hematopoietic stem cell transplantation-A case report. Pediatric Transplantation, 25(5), e13875. doi: 10.1111/petr.13875.
• Lee, H., Mantell, B. S., Richmond, M. E., Law, S. P., Zuckerman, W. A., Addonizio, L. J., Lee, T. M., & Lytrivi, I. D. (2020). Varying presentations of COVID-19 in young heart transplant recipients: A case series. Pediatric Transplantation, 24(8), e13780.doi: 10.1111/petr.13780. PMID: 32542914; PMCID: PMC7323105.
• Leidman, E., Duca, L. M., Omura, J. D., Proia, K., Stephens, J. W., & Sauber-Schatz, E. K. (2021). COVID-19 Trends Among Persons Aged 0-24 Years- United States, March 1-December 12, 2020. MMWR. Morbidity and mortality weekly report, 70(3), 88–94.doi: 10.15585/mmwr.mm7003e1.
• Li, H., Liu, S. M., Yu, X. H., Tang, S. L., & Tang, C. K. (2020). Coronavirus disease 2019 (COVID-19): current status and future perspectives. International journal of Antimicrobial Agents, 55(5), 105951. doi: 10.1016/j.ijantimicag.2020.105951.
• Liu, J. J., Bao, Y., Huang, X., Shi, J., & Lu, L. (2020). Mental health considerations for children quarantined because of COVID-19. The Lancet. Child & Adolescent Health, 4(5), 347–349.doi: 10.1016/S2352-4642(20)30096-1
• Liu, W., Zhang, Q., Chen, J., Xiang, R., Song, H., Shu, S., Chen, L., Liang, L., Zhou, J., You, L., Wu, P., Zhang, B., Lu, Y., Xia, L., Huang, L., Yang, Y., Liu, F., Semple, M. G., Cowling, B. J., Lan, K., … Liu, Y. (2020). Detection of Covid-19 in Children in Early January 2020 in Wuhan, China. The New England Journal of Medicine, 382(14), 1370–1371. doi: 10.1056/NEJMc2003717.
• Lu, Q., & Shi, Y. (2020). Coronavirus disease (COVID-19) and neonate: What neonatologist need to know. Journal of Medical Virology, 92(6), 564–567. doi: 10.1002/jmv.25740
• Lu, X., Xiang, Y., Du, H., & Wing-Kin Wong, G. (2020). SARS-CoV-2 infection in children- Understanding the immune responses and controlling the pandemic. Pediatric allergy and immunology: official publication of the European Society of Pediatric Allergy and Immunology, 31(5), 449–453.doi: 10.1111/pai.13267.
• Ludvigsson, J.F. (2020). Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr., 109(6),1088-1095. doi: 10.1111/apa.15270.
• McIntosh, K. (2021). Coronavirus disease 2019 (COVID-19): Epidemiology, virology, and prevention In: Hirsch MS, editors. UpToDate.2021.
• Menon, J., Shanmugam, N., Patel, K., Hakeem, A., Reddy, M. S., & Rela, M. (2020). Awareness and concerns about novel coronavirus disease 2019 (COVID-19) among parents of pediatric liver transplant recipients. Pediatric Transplantation, 24(8), e13805.doi: 10.1111/petr.13805.
• Minotti, C., Tirelli, F., Barbieri, E., Giaquinto, C., & Donà, D. (2020). How is immunosuppressive status affecting children and adults in SARS-CoV-2 infection? A systematic review. The Journal of İnfection, 81(1), e61–e66. doi: 10.1016/j.jinf.2020.04.026.
• Morand, A., Roquelaure, B., Colson, P., Amrane, S., Bosdure, E., Raoult, D., Lagier, J. C., & Fabre, A. (2020). Child with liver transplant recovers from COVID-19 infection. A case report. Archives de Pediatrie: Organe Officiel de la Societe Francaise de Pediatrie, 27(5), 275–276. doi: 10.1016/j.arcped.2020.05.004.
• National Association of School Nurses (NASN). (2021). Advocacy and leadership for inclusion in the planning process. Erişim linki: https://schoolnursenet.nasn.org/covid19ref/glossary/advocacy and-leadership-or-inclusion-in-the-planning-process
• National Institutes of Health (NIH). (2021). COVID-19 Treatment Guidelines. Erişim linki: https://www.covid19treatmentguidelines.nih.gov/therapeutic-management/ Palmore, T.N. &Simith, B.A. (2021). Coronavirus disease 2019 (COVID-19): Infection control in health care and home settings In: Sexton DJ, editors. UpToDate.2021.
• Park, S. E. (2020). Epidemiology, virology, and clinical features of severe acute respiratory syndrome -coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19). Clinical and Experimental Pediatrics, 63(4), 119–124. doi: 10.3345/cep.2020.00493
• Patel, N. A. (2020). Pediatric COVID-19: Systematic review of the literature. American Journal of Otolaryngology, 41(5), 102573.doi: 10.1016/j.amjoto.2020.102573.
• Safadi M. (2020). The intriguing features of COVID-19 in children and its impact on the pandemic. Jornal de Pediatria, 96(3), 265–268. doi: 10.1016/j.jped.2020.04.001.
• Salvatori, G., De Rose, D. U., Concato, C., Alario, D., Olivini, N., Dotta, A., & Campana, A. (2020). Managing COVID-19-Positive Maternal-Infant Dyads: An Italian Experience. Breastfeeding medicine: The Official Journal of the Academy of Breastfeeding Medicine, 15(5), 347–348.doi: 10.1089/bfm.2020.0095.
• Schwartz, S. P., Thompson, P., Smith, M., Lercher, D. M., Rimland, C. A., Bartelt, L., Park, Y. A., Weiss, S., Markmann, A. J., Raut, R., Premkumar, L., Kuruc, J., & Willis, Z. (2020). Convalescent Plasma Therapy in Four Critically Ill Pediatric Patients With Coronavirus Disease 2019: A Case Series. Critical Care Explorations, 2(10), e0237.doi: 10.1097/CCE.0000000000000237.
• Sheth, S., Shah, N., & Bhandari, V. (2020). Outcomes in COVID-19 Positive Neonates and Possibility of Viral Vertical Transmission: A Narrative Review. American Journal of Perinatology, 37(12), 1208–1216. doi: 10.1055/s-0040-1714719.
• Son, M.B. & Friedman K. (2021). Coronavirus disease 2019 (COVID-19): Multisystem inflammatory syndrome in children (MIS-C) management and outcome. In: Fulton DR, Kaplan SL, Sundel R, Randolph AG, editors. UpToDate.2021
• South, A. M., Brady, T. M., & Flynn, J. T. (2020). ACE2 (Angiotensin-Converting Enzyme 2), COVID-19, and ACE Inhibitor and Ang II (Angiotensin II) Receptor Blocker Use During the Pandemic: The Pediatric Perspective. Hypertension (Dallas, Tex.: 1979), 76(1), 16–22. doi: 10.1161/HYPERTENSIONAHA.120.15291.
• Tannuri, U., Tannuri, A., Cordon, M., & Miyatani, H. T. (2020). Low incidence of COVID-19 in children and adolescent post-liver transplant at a Latin American reference center. Clinics (Sao Paulo, Brazil), 75, e1986. doi: 10.6061/clinics/2020/e1986.
• Tezer, H. & Demirdağ. B. (2020). Novel coronavirus disease (COVID-19) in children. Turk J Med Sci. 50(SI-1): 592-603.
• T.C. Sağlık Bakanlığı Halk Sağlığı Müdürlüğü. (2020b). COVİD-19 Haftalık Durum Raporu 26.10.2020-30.10.2020. Erişim linki: https://COVID19.saglik.gov.tr/TR-68443/COVID-19-durum-raporu.html
• T.C. Sağlık Bakanlığı Halk Sağlığı Müdürlüğü. (2020c). COVID-19 Çocuk Hasta Yönetimi ve Tedavisi. Erişim linki: https://COVID19.saglik.gov.tr/Eklenti/38596/0/COVID-19rehbericocukhastayonetimivetedavipdf.pdf
• T.C. Sağlık Bakanlığı Halk Sağlığı Müdürlüğü. (2020d). COVID-19 İmmün (Konvalesan) Plazma Tedarik ve Klinik Kullanım Rehberi. Erişim linki: https://shgmkanhizmetleridb.saglik.gov.tr/Eklenti/39167/0/COVID-19-immun-plazma-rehberi-v5.pdf
• T.C. Sağlık Bakanlığı Halk Sağlığı Müdürlüğü. (2020e). COVID-19 Salgın Yönetimi ve Çalışma Rehberi. Erişim linki: https://covid19.saglik.gov.tr/Eklenti/40340/0/covid-19salginyonetimivecalismarehberipdf.pdf
• T.C. Sağlık Bakanlığı Halk Sağlığı Müdürlüğü (2021a). COVID-19 Genel Bilgiler, Epidemiyoloji ve Tanı. Erişim linki: https://covid19.saglik.gov.tr/Eklenti/39551/0/covid19rehberigenelbilgilerepidemiyolojivetanipdf.pdf.
• United Nations Educational, Scientific and Cultural Organization (UNESCO) (2020). Education: From disruption to recovery. Erişim linki: https://en.unesco.org/COVID19/educationresponse.
• United Nations International Children's Emergency Fund (UNİCEF) (2020). Coronavirüs disease (COVID-19): What parents should know. Erişim linki: https://www.unicef.org/stories/novel-coronavirus-outbreak-what-parents-should-know
• U.S. Food and Drug Administration (FDA). (2020). Investigational COVID-19 Convalescent Plasma: Guidance for Industry. Erişim linki:https://www.fda.gov/regulatory-information/search-fda-guidance-documents/investigational-COVID-19-convalescent-plasma
• Wang, S. S., Zhou, X., Lin, X. G., Liu, Y. Y., Wu, J. L., Sharifu, L. M., Hu, X. L., Rong, Z. H., Liu, W., Luo, X. P., Chen, Z., Zeng, W. J., Chen, S. H., Ma, D., Chen, L., & Feng, L. (2020). Experience of Clinical Management for Pregnant Women and Newborns with Novel Coronavirus Pneumonia in Tongji Hospital, China. Current Medical Science, 40(2), 285–289. doi: 10.1007/s11596-020-2174-4.
• World Health Organization (WHO) (2020a). Breastfeeding advice during the COVID-19 outbreak. Erişim linki: http://www.emro.who.int/nutrition/nutrition-infocus/breastfeeding-advice-during-COVID-19-outbreak.html
• World Health Organization (WHO) (2020b).Considerations for school-related public health measures in the context of COVID-19. Erişim linki: https://www.who.int/publications/i/item/considerations-for-school-related-public-health-measures-in-the-context-of-covid-19
• World Health Organization (WHO). (2021a). Coronavirus disease 2019 (COVID-19) Situation Report-79. Erişim Linki: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200408-sitrep-79-COVID-19.pdf?sfvrsn=4796b143_2
• World Health Organization (WHO). (2021b). COVID-19 Clinical management 2021. Erişim Linki: https://www.who.int/publications/i/item/WHO-2019-nCoV-clinical-2021-1(2021).
• World Health Organization (WHO). (2021c). Therapeutics and COVID-19 Lıvıng Guıdelıne 2020. Erişim Linki: https://www.who.int/publications/i/item/therapeutics-and-covid-19-living-guideline
• World Health Organization (WHO). (2021d). Avice on the use of masks for children in the community in the context of COVID-19. Erişim linki: https://apps.who.int/iris/rest/bitstreams/1296520/retrieve.
• World Health Organization (WHO) (2021e). Draft landscape of COVID-19 candidate vaccines. Erişim Linki: https://www.who.int/publications/m/item/draft-landscape-of-COVID-19-candidate-vaccines
• Yue, J., Zang, X., Le, Y., & An, Y. (2020). Anxiety, depression and PTSD among children and their parent during 2019 novel coronavirus disease (COVID-19) outbreak in China. Current Psychology (New Brunswick, N.J.), 1–8. Advance online publication.doi: 10.1007/s12144-020-01191-4.
• Zhong, Z., Zhang, Q., Xia, H., Wang, A., Liang, W., Zhou, W., Zhou, L., Liu, X., Rao, L., Li, Z., Peng, Z., Mo, P., Xiong, Y., Ye, S., Wang, Y., & Ye, Q. (2020). Clinical characteristics and immunosuppressant management of coronavirus disease 2019 in solid organ transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 20(7), 1916–1921.doi: 10.1111/ajt.15928.