Outcomes and complications of transarterial chemoembolization on colorectal cancer with liver metastases

Yıl 2018, Cilt: 15 Sayı: 3, 255 - 258, 12.12.2018

Muhammet Arslan , Serkan Değirmencioğlu Muhammed Tekinhatun , Atike Gökçen Demiray

Öz

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Background: To retrospectively evaluate the survival rates effectiveness and complications of transarterial chemoembolization on colorectal cancer with liver metastases.

Material and Methods: Fiftyseven patients (mean age 63) and 112 procedures with colorectal cancer liver metastases retrospectively underwent. Survival times and periprocedural complications were assessed.

Results: The treatment was tolerated well by all patients. Survival rate for 1 and 2 years from first transarterial chemoembolization was 58.4% and 26.5%, respectively. Median survival time was 18.5 months. There were 62 times postembolization syndrome in 32 patients after transarterial chemoembolization. One patient had abscess in liver after chemoembolization.

Conclusions: Transarterial chemoembolization is a minimally invasive treatment for liver metastases of colorectal carcinomas and has little major complications. Transarterial chemoembolization is one of an effective palliative treatment for metastatic colorectal cancer.

Anahtar Kelimeler

metastasis, colorectal carcinoma, liver, chemoembolization

Kolorektal kanserli hastaların karaciğer metastazlarına uygulanan transarteriyal kemoembolizasyon tedavisinin erken dönem sonuçları ve komplikasyonları

Öz

Amaç: Kolorektal kanserli hastaların karaciğer metastazlarına uygulanan transarteriyal kemoembolizasyon tedavisinin sağ kalıma etkisini ve işleme bağlı komplikasyonları değerlendirmeyi amaçladık.

Materyal ve Metod: Ortalama yaşları 63 olan 57 hasta ve 112 transarteriyal kemoembolizasyon işlemi retrospektif olarak tarandı. Dosya kayıtlarından hastaların sağ kalım oranları ve işleme bağlı komplikasyonları değerlendirildi.

Bulgular: Tüm hastalar transarteriyal kemoembolizasyon işlemini tolere etti. Hastalarımızda 1 yıllık sağ kalım oranı %58.4, 2 yıllık sağ kalım oranı 26.5 olarak hesaplandı. Ortalama sağ kalım 18.5 ay olarak bulundu. Toplam 32 hastada 62 kez postembolizasyon sendromu oluştuğu bir hastada ise işlem sonrası hepatik apse oluştuğu belirlendi.

Sonuç: Kolorektal kanserli hastaların karaciğer metastazlarına uygulanan transarteriyal kemoembolizasyon minimal invaziv ve düşük majör komplikasyon oranlarına sahip bir tedavi yöntemidir. Transarteriyal kemoembolizasyon metastatik karaciğerli kolorektal kanserli hastalarda etkili palyatif bir tedavi yöntemidir.

Anahtar Kelimeler

Karaciğer, metastaz, kolorektal kanser, kemoembolizasyon

Kaynakça

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