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Yıl 2021, Cilt: 4 Sayı: 1, 114 - 137, 15.04.2021
https://doi.org/10.38001/ijlsb.764602

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Kaynakça

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  • Referans15 Azevedo, M.F., et al., Rosmarinic acid, major phenolic constituent of Greek sage herbal tea, modulates rat intestinal SGLT1 levels with effects on blood glucose. Molecular nutrition & food research, 2011. 55(S1): p. S15-S25.
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Salvia fruticosa’nın (Anadolu Adaçayı) Terapötik Etkileri

Yıl 2021, Cilt: 4 Sayı: 1, 114 - 137, 15.04.2021
https://doi.org/10.38001/ijlsb.764602

Öz

Anadolu adaçayı (Salvia fruticosa), Lamiaceae familyasına ait bir bitki olup, Anadolu’da geleneksel halk hekimliğinde yaygın olarak kullanılmaktadır. Bitkinin yaprakları çay şeklinde tüketilir ve yapraklarından uçucu yağ elde edilir. Salvia fruticosa bitkisi farmasötik ajan olarak (antioksidan, antikanser, antimikrobiyal, antifungal, antihiperglisemik, antihipertansif vb.) kullanımı dışında aromaterapi, parfümeri ve kozmetik sektöründe; yiyeceklerde baharat, aroma verici ve koruyucu olarak pek çok alanda kullanıma sahiptir. Ancak bitkinin irrasyonel kullanımı ciddi yan etkilere ve komplikasyonlara yol açmaktadır. Bu derleme, Salvia fruticosa’nın botanik özelliklerini, uçucu yağ bileşenlerini, bu bileşenlerin potansiyel terapötik etkilerini ve neden olabileceği olası toksik etkileri değerlendirmeyi amaçlamaktadır.

Kaynakça

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  • Referans12 Delamare, A.P.L., et al., Antibacterial activity of the essential oils of Salvia officinalis L. and Salvia triloba L. cultivated in South Brazil. Food chemistry, 2007. 100(2): p. 603-608.
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  • Referans58 Bozan, B., et al., Antioxidant and free radical scavenging activities of eight Salvia species. Chemistry of Natural Compounds, 2002. 38(2): p. 198-200.
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  • Referans61 Durling, N.E., et al., Extraction of phenolics and essential oil from dried sage (Salvia officinalis) using ethanol–water mixtures. Food chemistry, 2007. 101(4): p. 1417-1424.
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  • Referans66 Abu-Dahab, R., et al., Mechanistic studies of antiproliferative effects of Salvia triloba and Salvia dominica (Lamiaceae) on breast cancer cell lines (MCF7 and T47D). Zeitschrift für Naturforschung C, 2014. 69(11-12): p. 443-451.
  • Referans67 Shih, H., G.V. Pickwell, and L.C. Quattrochi, Differential effects of flavonoid compounds on tumor promoter-induced activation of the human CYP1A2 enhancer. Archives of Biochemistry and Biophysics, 2000. 373(1): p. 287-294.
  • Referans68 Altay, A. and F. Bozoğlu, Salvia fruticosa modulates mRNA expressions and activity levels of xenobiotic metabolizing CYP1A2, CYP2E1, NQO1, GPx, and GST enzymes in human colorectal adenocarcinoma HT-29 cells. Nutrition and cancer, 2017. 69(6): p. 892-903.
  • Referans 69 Akaberi, M., S. Mehri, and M. Iranshahi, Multiple pro-apoptotic targets of abietane diterpenoids from Salvia species. Fitoterapia, 2015. 100: p. 118-132.
  • Referans70 Gali-Muhtasib, H. and N. Affara, Chemopreventive effects of sage oil on skin papillomas in mice. Phytomedicine, 2000. 7(2): p. 129-136.
  • Referans71 Kaileh, M., et al., Screening of indigenous Palestinian medicinal plants for potential anti-inflammatory and cytotoxic activity. Journal of ethnopharmacology, 2007. 113(3): p. 510-516.
  • Referans72 Badisa, R., et al., Cytotoxic Activities of Salvia of the Labiatae Family. Pharmaceutical biology, 2005. 42(8): p. 640-645.
  • Referans73 Agarwal, R., Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents. Biochemical pharmacology, 2000. 60(8): p. 1051-1059.
  • Referans74 Kan, S.F., et al., Anti‐proliferative effects of evodiamine on human prostate cancer cell lines DU145 and PC3. Journal of cellular biochemistry, 2007. 101(1): p. 44-56.
  • Referans75 Ramos, A.A., et al., Polyphenolic compounds from Salvia species protect cellular DNA from oxidation and stimulate DNA repair in cultured human cells. Journal of agricultural and food chemistry, 2010. 58(12): p. 7465-7471.
  • Referans76 Al-Kalaldeh, J.Z., R. Abu-Dahab, and F.U. Afifi, Volatile oil composition and antiproliferative activity of Laurus nobilis, Origanum syriacum, Origanum vulgare, and Salvia triloba against human breast adenocarcinoma cells. Nutrition Research, 2010. 30(4): p. 271-278.
  • Referans77 Abu-Dahab, R., et al., Comparison of the antiproliferative activity of crude ethanol extracts of nine salvia species grown in Jordan against breast cancer cell line models. Pharmacognosy magazine, 2012. 8(32): p. 319.
  • Referans78 Sevindik, N. and E. Rencuzogullari, The genotoxic and antigenotoxic effects of Salvia fruticosa leaf extract in human blood lymphocytes. Drug and chemical toxicology, 2014. 37(3): p. 295-302.
  • Referans79 Fraihat, A., et al., Inhibitory effects of methanol extracts of selected plants on the proliferation of two human melanoma cell lines. Tropical Journal of Pharmaceutical Research, 2018. 17(6): p. 1081-1086.
  • Referans80 Koutsoulas, A., et al., Characterization of phenolic compounds and antiproliferative effects of Salvia pomifera and Salvia fruticosa extracts. Molecules, 2019. 24(16): p. 2921.
  • Referans81 Eltawaty, S.I., et al., Anticancer effects of methanol extract of Libyan Salvia fruticosa Mill. on MCF7, T47D and (MDA-MB-468) breast cells lines. European Journal of Pharmaceutical and Medical Research, 7(2): p. 165-169.
  • Referans82 Folkman, S. and R.S. Lazarus, Stress, appraisal, and coping. 1984: New York: Springer Publishing Company.
  • Referans83 Hur, J.M., et al., Cryptotanshinone but not tanshinone IIA inhibits angiogenesis in vitro. Experimental & molecular medicine, 2005. 37(2): p. 133-137.
  • Referans84 Jung, H.-J., et al., Anti-inflammatory, anti-angiogenic and anti-nociceptive activities of an ethanol extract of Salvia plebeia R. Brown. Journal of ethnopharmacology, 2009. 126(2): p. 355-360.
  • Referans85 Keshavarz, M., et al., In vitro and ex vivo antiangiogenic activity of Salvia officinalis. Phytotherapy Research, 2010. 24(10): p. 1526-1531.
  • Referans86 Liu, F., et al., Effect of Salvia chinensis extraction on angiogenesis of tumor. Zhongguo Zhong yao za zhi= Zhongguo zhongyao zazhi= China journal of Chinese materia medica, 2012. 37(9): p. 1285-1288.
  • Referans87 Perry, N.S., et al., In‐vitro inhibition of human erythrocyte acetylcholinesterase by Salvia lavandulaefolia essential oil and constituent terpenes. Journal of pharmacy and pharmacology, 2000. 52(7): p. 895-902.
  • Referans88 Savelev, S.U., E.J. Okello, and E.K. Perry, Butyryl‐and acetyl‐cholinesterase inhibitory activities in essential oils of Salvia species and their constituents. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 2004. 18(4): p. 315-324.
  • Referans89 Orhan, I.E., et al., Assessment of anticholinesterase and antioxidant properties of selected sage (Salvia) species with their total phenol and flavonoid contents. Industrial Crops and Products, 2013. 41: p. 21-30.
  • Referans90 Orhan, I. and M. Aslan, Appraisal of scopolamine-induced antiamnesic effect in mice and in vitro antiacetylcholinesterase and antioxidant activities of some traditionally used Lamiaceae plants. Journal of Ethnopharmacology, 2009. 122(2): p. 327-332.
  • Referans91 Şenol, F.S., et al., Evaluation of cholinesterase inhibitory and antioxidant activities of wild and cultivated samples of sage (Salvia fruticosa) by activity-guided fractionation. Journal of medicinal food, 2011. 14(11): p. 1476-1483.
  • Referans92 Topçu, G., et al., Terpenoids, essential oil composition, fatty acid profile, and biological activities of Anatolian Salvia fruticosa Mill. Turkish Journal of Chemistry, 2013. 37(4): p. 619-632.
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  • Referans95 Arabiyat, S., et al., Antilipolytic and hypotriglyceridemic effects of dietary Salvia triloba Lf (Lamiaceae) in experimental rats. Tropical Journal of Pharmaceutical Research, 2016. 15(4): p. 723-728.
  • Referans96 Cam, M.E., et al., Antidiabetic effects of Salvia triloba and Thymus praecox subsp. skorpilii var. skorpilii in a rat model of streptozotocin/nicotinamide-induced diabetes. Marmara Pharmaceutical Journal, 2017. 21(4): p. 818-827.
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  • Referans98 Daradka, H.M., The effect of Salvia fruticosa ingestion on male rat sexual behavior. Res J Biol Sci, 2009. 4(12): p. 1288-91.
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  • Referans100 Anwar, M.A., et al., Salvia fruticosa induces vasorelaxation in rat isolated thoracic aorta: role of the PI3K/Akt/eNOS/NO/cGMP signaling pathway. Scientific reports, 2017. 7(1): p. 1-14.
  • Referans101 Millet, Y., et al., Toxicity of some essential plant oils. Clinical and experimental study. Clinical toxicology, 1981. 18(12): p. 1485-1498.
  • Referans102 Millet, Y., et al., Experimental study of the toxic convulsant properties of commercial preparations of essences of sage and hyssop (author's transl). Revue d'electroencephalographie et de neurophysiologie clinique, 1979. 9(1): p. 12-18.
  • Referans103 Elisabetsky, E., J. Marschner, and D.O. Souza, Effects of linalool on glutamatergic system in the rat cerebral cortex. Neurochemical research, 1995. 20(4): p. 461-465.
  • Referans104 Farhat, G., N. Affara, and H. Gali-Muhtasib, Seasonal changes in the composition of the essential oil extract of East Mediterranean sage (Salvia libanotica) and its toxicity in mice. Toxicon, 2001. 39(10): p. 1601-1605.
  • Referans105 Harmancı, K., et al., Elma yağının yanlış kullanımına bağlı gelişen kimyasal pnömonili bir olgu. Asthma Allergy Immunol, 2011. 9: p. 101-1.
  • Referans106 Gündüz, S., et al., Acı elma yağının yanlış kullanımına bağlı dört zehirlenme vakası. Dicle Tıp Dergisi, 2016. 43(2): p. 364-366.
Toplam 106 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Yapısal Biyoloji , Gıda Mühendisliği, Ziraat Mühendisliği (Diğer)
Bölüm Derleme Makaleler
Yazarlar

Sinem Elmas 0000-0002-2872-9990

Onur Elmas Bu kişi benim 0000-0002-8380-0999

Yayımlanma Tarihi 15 Nisan 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 4 Sayı: 1

Kaynak Göster

EndNote Elmas S, Elmas O (01 Nisan 2021) Salvia fruticosa’nın (Anadolu Adaçayı) Terapötik Etkileri. International Journal of Life Sciences and Biotechnology 4 1 114–137.


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