Unusual finding on bone scintigraphy: Cerebral 99m-tc mdp involvement

Yıl 2024, Cilt: 15 Sayı: 52, 96 - 98, 02.09.2024

Edanur Ekinci , Ebuzer Kalender , Yusuf Burak Çayırlı

https://doi.org/10.17944/interdiscip.1409955

Öz

99mTc-MDP (99mTc-methylene diphosphonate) uptake in the brain parenchyma was observed in the scintigraphic imaging of a 56 years old male patient with renal cell carcinoma (RCC), who was referred to our clinic for metastasis screening due to widespread bone pain. Uptake of 99mTc-MDP in the brain parenchyma in bone scintigraphy is a rare finding. This case is presented to reveal the causes of cerebral 99mTc-MDP involvement.

Anahtar Kelimeler

bone scintigraphy, 99m-Tc MDP, SVO

Kaynakça

• Gnanasegaran G, Cook G, Adamson K, Fogelman I. Patterns. Variants, artifacts, and pitfalls in conventional radionuclide bone imaging and SPECT/CT. Semin Nucl Med. 2009;39(6):380-95. https://doi.org/10.1053/j.semnuclmed.2009.07.003
• O'Connor MK, Brown ML, Hung JC, Hayostek RJ. The art of bone scintigraphy--technical aspects. J Nucl Med. 1991;32(12):2332-41.
• Horger M, Bares R. The role of single-photon emission computed tomography/computed tomography in benign and malignant bone disease. Semin Nucl Med. 2006;36(4):286-94. https://doi.org/10.1053/j.semnuclmed.2006.05.001
• Mohd Rohani MF, Zanial AZ, Suppiah S, et al. Bone single-photon emission computed tomography/computed tomography in cancer care in the past decade: a systematic review and meta-analysis as well as recommendations for further work. Nucl Med Commun. 2021;42(1):9-20. https://doi.org/10.1097/MNM.0000000000001306
• Van den Wyngaert T, Strobel K, Kampen WU, et al; EANM Bone & Joint Committee and the Oncology Committee. The EANM practice guidelines for bone scintigraphy. Eur J Nucl Med Mol Imaging. 2016;43(9):1723-38. https://doi.org/10.1007/s00259-016-3415-4
• O'Sullivan JM, Cook GJ. A review of the efficacy of bone scanning in prostate and breast cancer. Q J Nucl Med. 2002;46(2):152-9.
• Love C, Din AS, Tomas MB, Kalapparambath TP, Palestro CJ. Radionuclide bone imaging: an illustrative review. Radiographics. 2003;23(2):341-58. https://doi.org/10.1148/rg.232025103
• Nuclear Medicine in Clinical Diagnosis and Treatment, 3rd ed. AJNR Am J Neuroradiol. 2006;27(2):464–5.
• Crawshaw JW, Allan R. Middle cerebral artery infarct demonstrated on bone scintigraphy. Eur J Nucl Med Mol Imaging. 2007;34(2):306. https://doi.org/10.1007/s00259-006-0181-8
• Zuckier LS, Martineau P. Altered biodistribution of radiopharmaceuticals used in bone scintigraphy. Semin Nucl Med. 2015;45(1):81-96. https://doi.org/10.1053/j.semnuclmed.2014.07.007
• Peller PJ, Ho VB, Kransdorf MJ. Extraosseous Tc-99m MDP uptake: a pathophysiologic approach. Radiographics. 1993;13(4):715-34. https://doi.org/10.1148/radiographics.13.4.8356264