KOŞUCULARDA ACTN3 VE ACE GENLERİNİN SPORTİF PERFORMANSA ETKİSİ

Yıl 2020, Cilt: 7 Sayı: 1, 1 - 12, 01.04.2020

Celal Bulgay , Ebru Cetın , Özlem Orhan , Prof.dr. Mehmet Ali Ergün

Öz

Çalışmanın amacı, atletizm sporcularının performansında rol oynayabilecek genlerle ilgili kanıtları eleştirel olarak incelemek ve gelecekteki atletlerin başarısını tanımlamak için genetik testin öngörücü faydasına ilişkin fikir vermektir. Sportif performansı etkileyen genler her geçen yıl bilim insanı için büyük bir araştırma konusu olmuştur. Yaklaşık olarak 250 genin sportif performans üzerinde etkisi olduğu düşünülmektedir. Atletlerde performans açısından etkili olduğu düşünülen anjiyotensin dönüştürücü enzim (ACE) ve Alfa Actinin- 3 (ACTN3) genleridir. Yapılan derleme de günümüze kadar Pubmed ve Google Akademik veri tabanlarından ulaşılan çalışmalar bir araya getirilerek özetlenmiştir. Derleme çalışmasında incelenen literatür doğrultusunda sportif performanstan sorumlu önemli genetik değişkenlerden olan ACTN3 ve ACE genlerinin sporcu olmaya aday bireylerin yetenek taramasında, kas hasarı düzeyine, spor branşlarının belirlenmesinde, branş içi yönlendirmede ve uygun antrenman uygulanmasında etkili olabileceği düşünülmektedir. Sonuç olarak; sportif performansı artırmada genetik faktörlerin önemli bir yere sahip olduğu ancak çevresel faktörlerin de etkisi olduğu söylenebilir. Uygun genetik yapıya sahip bireyler ancak uygun antrenman modelleri uygulandığında istedikleri başarıya ulaşabilirler.

Anahtar Kelimeler

Atletizm,, Koşucular,, Performans, Genetik, ACE, ACTN3

Kaynakça

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