Bir ben var benden içeri; Kimerizm

Yıl 2016, Cilt: 2 Sayı: 1, 1 - 6, 31.12.2015

İlknur Keskin , Tangül Müdok

Öz

ÖZET

Tıp literatüründe “Kimerizm” terimi, farklı organizmalara ait genetik yapıların bir arada bulunduğu, yeni, farklı ve ortak bir bütünü oluşturduğu durumları ifade etmek için kullanılır. Kimerik birey, kendi DNA’sının yanısıra dünyaya gelmeyenikizinin de DNA’sını taşır. Kaynaşma embriyo aşamasında iken gerçekleştiğinden dolayı, doku veya organ reddi olmaz. En sık ve doğal kimerizm sebebi gebeliktir..

Henüz cevap bulamamış sorular mevcut olmakla birlikte, başka faktörlerin de eklenmesi ile kimerizm’in insan sağlığında çok önemli bir yeri olduğu düşünülmektedir. Gerek otoimmün gerekse otoimmün olmayan hastalıklar ile olan yakın ilişkisi birçok çalışmaya konu konmuştur.

 

 

Anahtar Kelimeler

Kimerizm, Mikrokimerizm, Otoimmün hastalıklar, Prenatal tanı

Kaynakça

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