The volatile compounds of some edible wild plants consumed in the Mediterranean region

Yıl 2024, , 710 - 728, 29.09.2024

Aslıhan Cesur Turgut

https://doi.org/10.31015/jaefs.2024.3.25

Öz

In this study, 13 different edible weed species [Centaurea depressa Bieb., Cichorium intybus L., Lactuca serriola L., Malva neglecta Wallr., Papaver dubium L., Polygonum cognatum Meissn., Rumex patientia L., Scorzonera cana (C.A.Mey.Hoffm.), Silene alba (Mill.) Krause, Stellaria media L., Sonchus oleraceus L., Taraxacum officinale, Tragopogon longirostris Bisch] were collected from the same location in the Mediterranean region. Then, the leaves of all species were analyzed by the SPME-GC/MS method for the detection of volatile compounds. The compounds were grouped according to their structures as alcohols, aldehydes, alkanes, ester, furans, hydrocarbons, ketones, sulfur compounds, and terpenes. The percentages of the terpenes, aldehydes and alcoholic compounds were found to have the highest ratios of volatile compounds, respectively. The species found with the highest total terpene percentage was Sonchus oleraceus L. (78.84%), while the lowest one was Stellaria media L. (51.03%). Similarly, the highest total aldehydes percentage was found in Stellaria media L. (38.41%), and the lowest was in Centaurea depressa Bieb. (4.62%). Lastly, the highest total alcohol percentage was observed in Centaurea depressa Bieb. (9.92%) and the lowest was in Malva neglecta Wallr. (1.11%). The limonene, which is an important monoterpene, among 63 components, was found to be the major component in all species with a range of approximately 51-79%. Among them, Sonchus oleraceus L. had the highest limonene content (78.84%).

Anahtar Kelimeler

Volatile compounds, Terpene, Limonene, SPME GC/MS, Wild species

Kaynakça

• Abdalla, M. A. and Zidorn, C. (2020). The genus Tragopogon (Asteraceae): a review of its traditional uses, phytochemistry, and pharmacological properties. Journal of Ethnopharmacology, 250, 112466. https://doi.org/10.1016/j.jep.2019.112466
• Abdul-Jalil, T. Z. (2020). Lactuca serriola: short review of its phytochemical and pharmacological profiles. International Journal of Drug Delivery Technology, 10(03), 505-508. https://doi.org/10.25258/ijddt.10.3.34
• Acikara, O. B., Çitoğlu, G. S., & Çoban, T. (2013). Phytochemical Screening and Antioxidant Activities of Selected Scorzonera Species. Turkish Journal of Pharmaceutical Sciences, 10(3), 453-462.
• Akbulut, S. and Zengin, Z. (2023). Ethnobotanical survey of wild plants used in Gümüşhane province (Turkey). Boletin Latinoamericano Y Del Caribe De Plantas Medicinales Y Aromaticas, 22(2), 237-254. https://doi.org/10.37360/blacpma.23.22.2.18
• Akgöz, Y. (2014). Biological and antioxidant activities of Silene sp.. International Research Journal of Pharmacy, 5(11), 810-813. https://doi.org/10.7897/2230-8407.0511166
• Akpınar, R., Yıldırım Baştemur, G., Bıçak, B., Sanli, N. O., Mertoğlu Kamalı, E., Pekmez, M., Kecel Gündüz, S., & Perçin Özkorucuklu, S. (2023). Phytochemical profiling, in vitro biological activities, and in silico (molecular docking and absorption, distribution, metabolism, excretion, toxicity) studies of Polygonum cognatum Meissn. Journal of Separation Science, 47(1). https://doi.org/10.1002/jssc.202300750
• Al‐Rimawi, F., Rishmawi, S., Ariqat, S. H., Khalid, M., Warad, I., & Salah, Z. (2016). Anticancer activity, antioxidant activity, and phenolic and flavonoids content of wild Tragopogon porrifolius plant extracts. Evidence-Based Complementary and Alternative Medicine, 2016(1). https://doi.org/10.1155/2016/9612490
• Al-Qurashy, N. N. A. (2023). Antibacterial and antifungal activity of the extract of medicinal plant Malva neglecta Wallr. Journal of Wasit for Science and Medicine, 10(1), 1-6. https://doi.org/10.31185/jwsm.407
• Alasalvar, C., Topal, B., Serpen, A., Bahar, B., Pelvan, E., & Gökmen, V. (2012). Flavor characteristics of seven grades of black tea produced in Turkey. Journal of Agricultural and Food Chemistry, 60(25), 6323-6332. https://doi.org/10.1021/jf301498p
• Amao, I. (2018). Health benefits of fruits and vegetables: Review from Sub-Saharan Africa. Vegetables: importance of quality vegetables to human health, 22, 33-53. https://doi.org/10.5772/intechopen.74472
• Andalib, F., Moosavian, H., Khazraeinia, P., Mohajerani, S., & Pourakbari, S. (2021). Comparison of hepatoprotective activity of Cichorium intybus and Cynara scolymus extracts against paracetamol induced hepatotoxicity in broiler chicken. Egyptian Journal of Veterinary Sciences, 52(2), 251-256. https://doi.org/10.21608/ejvs.2021.48017.1200
• Aziz, M. A., Adnan, M., Khan, A., Rehman, A. U., Jan, R., & Khan, J. (2016). Ethno-medicinal survey of important plants practiced by indigenous community at ladha subdivision, south waziristan agency, Pakistan. Journal of Ethnobiology and Ethnomedicine, 12(1). https://doi.org/10.1186/s13002-016-0126-7
• Barthelmess, E. L., Richards, C. M., & McCauley, D. E. (2005). Relative effects of nocturnal vs diurnal pollinators and distance on gene flow in small Silene alba populations. New Phytologist, 169(4), 689-698. https://doi.org/10.1111/j.1469-8137.2005.01580.x
• Baydoun, S., Hani, N., Nasser, H., Ulian, T., & Arnold-Apostolides, N. (2023). Wild leafy vegetables: a potential source for a traditional mediterranean food from Lebanon. Frontiers in Sustainable Food Systems, 6. https://doi.org/10.3389/fsufs.2022.991979
• Bezerra, M. S., Zeferino, K. S., Menezes, L. D., Bezerra, A. S., Lopes, L. Q. S., & Marquezan, F. K. (2022). Antimicrobial and antibiofilm activities of Cichorium intybus: a review. Research, Society and Development, 11(2), e10911225384. https://doi.org/10.33448/rsd-v11i2.25384
• Bushra, I., Fozia, F., Waheed, A., Rehman, A., Ullah, H., Iqbal, H., Wahap, A., Almas, M., & Ahmad, I. (2012). Antimicrobial activity of Malva neglecta and Nasturtium microphyllum. International Journal of Research in Ayurveda and Pharmacy, 3(6), 808-810. https://doi.org/10.7897/2277-4343.03624
• Butnariu, M., Quispe, C., Herrera‐Bravo, J., Pentea, M., Sărac, I., Küşümler, A. S., Özçelik, B., Painuli, S., Semwal, P., Imran, M., Gondal, T.A., Emamzadeh-Yazdi, S., Lapava, N., Yousaf, Z., Kumar, M., Eid, A.H., Al-Dhaheri, Y., Suleria, H.A.R., Contreras, M.M., Sharifi-Rad, J., & Cho, W. C. (2022). Papaver plants: current insights on phytochemical and nutritional composition along with biotechnological applications. Oxidative Medicine and Cellular Longevity, 2022, 1-23. https://doi.org/10.1155/2022/2041769
• Caporaso, N. & Sacchi, R. (2021). Flavor chemistry of virgin olive oil: an overview. Applied Sciences, 11(4), 1639. https://doi.org/10.3390/app11041639
• Carev, I., Golemac, A., Siljak-Yakovlev, S., Pellay, F. X., & Politeo, O. (2022). Volatile Oil Chemical Composition of Wild, Edible Centaurea scabiosa L. and Its Cytotoxic Activity. Plants, 11(23), 3267. https://doi.org/10.3390/plants11233267
• Casado-Hidalgo, G., Pérez-Quintanilla, D., Morante‐Zarcero, S., & Sierra, I. (2021). Mesostructured silica-coated magnetic nanoparticles to extract six opium alkaloids in poppy seeds prior to ultra-high-performance liquid chromatography-tandem mass spectrometry analysis. Foods, 10(7), 1587. https://doi.org/10.3390/foods10071587
• Chak, P. O. O. J. A., Chaudhary, D., Jain, S. O. N. I. K. A., Soni, P., Jain, P. K., Dwivedi, J. A. Y. A., & Sharma, S. (2021). Phytochemical and gas chromatography-mass spectrometry analysis of Chenopodium album and Stellaria media. Indian Journal of Pharmaceutical Sciences, 83(6), 1261-72. https://doi.org/10.36468/pharmaceutical-sciences.881
• Chak, P., Chaudhary, D., Jain, S., Soni, P., Jain, P., Dwivedi, J., & Sharma, S. (2021). Phytochemical and gas chromatography-mass spectrometry analysis of Chenopodium album and Stellaria media. Indian Journal of Pharmaceutical Sciences, 83(6). https://doi.org/10.36468/pharmaceutical-sciences.881
• Chen, L., Xia, F., Lin, X., Liu, Q., Zengin, G., Delmas, D., Paoli, P., Teng H. & Xiao, J. (2019). Phenolic extract from Sonchus oleraceus L. protects diabetes‐related liver injury in rats through TLR4/NF‐ΚB signaling pathway. eFood, 1(1), 77-84. https://doi.org/10.2991/efood.k.191018.002
• Chen, X., Ding, Y., Guan, H., Zhou, C., He, X., Shao, Y., Wang, Y.-B., Wang, N., Li, B., Lv, G.-Y. & Chen, S. (2024). The pharmacological effects and potential applications of limonene from citrus plants: a review. Natural Product Communications, 19(5). https://doi.org/10.1177/1934578x241254229
• Cho, K. S., Lim, Y. R., Lee, K., Lee, J., Lee, J. H., & Lee, I. S. (2017). Terpenes from forests and human health. Toxicological Research, 33, 97-106. https://doi.org/10.5487/TR.2017.33.2.097
• Demirpolat, A. (2022). Chemical composition of essential oils of seven polygonum species from Turkey: A chemotaxonomic approach. Molecules, 27(24), 9053. https://doi.org/10.3390/molecules27249053
• Demirgül, F., Divriklioğlu-Kundak, M., & Sağdıç, O. (2022). Bioactive properties, antibacterial activity, and color features of polygonum cognatum: the effects of frozen storage and cooking process. Food Science and Technology, 42. https://doi.org/10.1590/fst.00322
• Demján, V., Sója, A., Kiss, T., Fejes, A., Gausz, F. D., Szűcs, G., Siska, A., Földesi I., Tengölics, R., Darula Z., Csupor, D., Pipicz, M. & Csont, T. (2022). Stellaria media tea protects against diabetes-induced cardiac dysfunction in rats without affecting glucose tolerance. Journal of Traditional and Complementary Medicine, 12(3), 250-259. https://doi.org/10.1016/j.jtcme.2021.08.003
• Deveci, E. (2022). LC‐ESI‐MS/MS‐based phytochemicals and cytotoxic, antioxidant, and enzyme inhibitory activities of Scorzonera mollis subsp. Szowitzii: a new reserve of bioactive compounds. Journal of Food Processing and Preservation, 46(4). https://doi.org/10.1111/jfpp.16478
• Dias, J. S. (2012). Major classes of phytonutriceuticals in vegetables and health benefits: a review. Journal of Nutritional Therapeutics, 1(1), 31-62. https://doi.org/10.6000/1929-5634.2012.01.01.5
• Dias, J.S. & Imai, S. (2017). Vegetables consumption and its benefits on diabetes. Journal of Nutritional Therapeutics, 6(1), 1-10. https://doi.org/10.6000/1929-5634.2017.06.01.1
• Dongare, P. N., Kadu, T. B., Pohane, A. L., Dighade, S. J., & Patil, P. G. (2021). Review on pharmacognosy, phytochemistry and pharmacological activity of Taraxacum officinale (dandelion plant). World Journal of Advanced Research and Reviews, 12(2), 212-118. https://doi.org/10.30574/wjarr.2021.12.2.0570
• Dudareva, N., Pichersky, E., & Gershenzon, J. (2004). Biochemistry of plant volatiles. Plant Physiology, 135(4), 1893-1902. https://doi.org/10.1104/pp.104.049981
• El‐Hawary, S. A., Sokkar, N. M., Ali, Z. Y., & Yehia, M. M. (2011). A profile of bioactive compounds of Rumex vesicarius L. Journal of Food Science, 76(8), C1195-C1202. https://doi.org/10.1111/j.1750-3841.2011.02370.x
• Epure, A., Pârvu, A., Vlase, L., Benedec, D., Hanganu, D., Oniga, O., Vlase, A.-M., Ielciu, I., Toiu, A., & Oniga, I. (2023). New approaches on the anti-inflammatory and cardioprotective properties of Taraxacum officinale tincture. Pharmaceuticals, 16(3), 358. https://doi.org/10.3390/ph16030358
• Erasto, P. and Viljoen, A. (2008). Limonene - a review: biosynthetic, ecological and pharmacological relevance. Natural Product Communications, 3(7),1934578X0800300. https://doi.org/10.1177/1934578x0800300728
• Erdoğan, T., Gönenç, T. M., Çakılcıoğlu, U., & Kıvçak, B. (2014). Fatty acid composition of the aerial parts of some Centaurea species in Elazig, Turkey. Tropical Journal of Pharmaceutical Research, 13(4), 613. https://doi.org/10.4314/tjpr.v13i4.19
• Eruygur, N., Uçar, E., Ataş, M., Ergül, M., & Sözmen, F. (2020). Determination of biological activity of Tragopogon porrifolius and Polygonum cognatum consumed intensively by people in Sivas. Toxicology Reports, 7, 59-66. https://doi.org/10.1016/j.toxrep.2019.12.002
• Esmaeili, A., Rustaiyan, A., Nadimi, M., Masoudi, S., Tadayon, F., Sedaghat, S., Ebrahimpur, N., & Hajyzadeh, E. (2005). Volatile constituents of Centaurea depressa MB and Carduus pycnocephalus L. two compositae herbs growing wild in Iran. Journal of Essential Oil research, 17(5), 539-541. https://doi.org/10.1080/10412905.2005.9698988
• Espina, L., Gelaw, T. K., Lamo-Castellví, S. d., Pagán, R., & García-Gonzalo, D. (2013). Mechanism of bacterial inactivation by (+)-limonene and its potential use in food preservation combined processes. Public Library of Science One, 8(2), e56769. https://doi.org/10.1371/journal.pone.0056769
• Fan, F., Zhou, S., Qian, H., Zong, B., Huang, C., Zhu, R., Guo, H-W., & Gong, S. (2022). Effect of yellowing duration on the chemical profile of yellow tea and the associations with sensory traits. Molecules, 27(3), 940. https://doi.org/10.3390/molecules27030940
• Farzaei, M. H., Rahimi, R., Attar, F., Siavoshi, F., Saniee, P., Hajimahmoodi, M., Mirnezami, T., & Khanavi, M. (2014). Chemical composition, antioxidant and antimicrobial activity of essential oil and extracts of Tragopogon graminifolius, a medicinal herb from İran. Natural Product Communications, 9(1), 1934578X1400900. https://doi.org/10.1177/1934578x1400900134
• Fukuda, T., Okazaki, K., & Shinano, T. (2013). Aroma characteristic and volatile profiling of carrot varieties and quantitative role of terpenoid compounds for carrot sensory attributes. Journal of Food Science, 78(11). https://doi.org/10.1111/1750-3841.12292
• Fulton, S., Cardwell, C., McKinley, M., & Woodside, J. V. (2011). The effect of increasing fruit and vegetable consumption on overall diet: a systematic review and meta-analysis. Proceedings of the Nutrition Society, 70(OCE3). https://doi.org/10.1017/s0029665111001066
• García-Carrasco, B., Fernández-Dacosta, R., Dávalos, A., Ordovás, J. M., & Rodrı́guez-Casado, A. (2015). In vitro hypolipidemic and antioxidant effects of leaf and root extracts of Taraxacum officinale. Medical Sciences, 3(2), 38-54. https://doi.org/10.3390/medsci3020038
• Ghaderi, R., Zardast, M., Hosseini, M. K., Delgir, B., & Hassanpour, M. (2012). Comparison of antibacterial effect of Cichorium intybus L. with vancomycin, ceftriaxone, ciprofloxacin and penicillin (in vitro). Clinical and Experimental Pharmacology, 02(02). https://doi.org/10.4172/2161-1459.1000113
• Gomaa, N. H., Hassan, M. O., Fahmy, G. M., González, L., Hammouda, O., & Atteya, A. M. (2014). Allelopathic effects of Sonchus oleraceus L. on the germination and seedling growth of crop and weed species. Acta Botanica Brasilica, 28(3), 408-416. https://doi.org/10.1590/0102-33062014abb3433
• Gözcü, S., Uğan, R. A., Özbek, H., Gündoğdu, B., & Güvenalp, Z. (2023). Evaluation of antidiabetic and antioxidant effects of Polygonum cognatum Meisn. and phytochemical analysis of effective extracts. Biomedical Chromatography, 38(3). https://doi.org/10.1002/bmc.5809
• Guo, L., Huang, L., Cheng, X., Gao, Y., Zhang, X., Yuan, X., Xue, C., & Chen, X. (2022). Volatile flavor profile and sensory properties of vegetable soybean. Molecules, 27(3), 939. https://doi.org/10.3390/molecules27030939
• Gürbüz, İ., Özkan, A. M. G., Yeşilada, E., & Kutsal, O. (2005). Anti-ulcerogenic activity of some plants used in folk medicine of pinarbasi (kayseri, turkey). Journal of Ethnopharmacology, 101(1-3), 313-318. https://doi.org/10.1016/j.jep.2005.05.015
• Hidajat, M. J., Jo, W., Kim, H., & Noh, J. (2020). Effective droplet size reduction and excellent stability of limonene nanoemulsion formed by high-pressure homogenizer. Colloids and Interfaces, 4(1), 5. https://doi.org/10.3390/colloids4010005
• Honěk, A. and Martinková, Z. (2010). Body size and the colonisation of cereal crops by the invasive slug Arion lusitanicus. Annals of Applied Biology, 158(1), 79-86. https://doi.org/10.1111/j.1744-7348.2010.00442.x
• Hong, J. & Gruda, N. (2020). The potential of introduction of Asian vegetables in Europe. Horticulturae, 6(3), 38. https://doi.org/10.3390/horticulturae6030038
• Hussein, I. A., Radhakrishnan, S., El‐Hela, A. A., Mohammad, A. I., & Ross, S. A. (2019). Antimicrobial secondary metabolites from Silene rubella growing in Egypt. Journal of Biomedical and Pharmaceutical Research, 8(6). https://doi.org/10.32553/jbpr.v8i6.694
• Hussein, M. A. and Gobba, N. A. (2014). Biochemical study on rule of Sonchus oleraceus L. extracts against paracetamol-induced liver toxicity. Scientific Journal of October 6 University, 2(1), 1-11. https://doi.org/10.21608/sjou.2014.32865
• Ibrahim, L., Saleh, A., Ammar, M., Mansour, M., & El-Hamid, H. A. (2022). Allelopathic effect of some wild species on germination and growth of Bidens pilosa. Advances in Environmental and Life Sciences, 3(1), 21-30. https://doi.org/10.21608/aels.2022.177060.1025
• İlgün, S., Akkol, E. K., İlhan, M., Polat, D. Ç., Kılıç, A. B., Coşkun, M., & Sobarzo‐Sánchez, E. (2020). Sedative effects of latexes obtained from some Lactuca L. species growing in Turkey. Molecules, 25(7), 1587. https://doi.org/10.3390/molecules25071587
• Jędrzejczyk, I. and Rewers, M. (2020). Identification and genetic diversity analysis of edible and medicinal Malva species using flow cytometry and ISSR molecular markers. Agronomy, 10(5), 650. https://doi.org/10.3390/agronomy10050650
• Jerković, I., Marijanović, Z., Kranjac, M., & Radonić, A. (2015). Comparison of different methodologies for detailed screening of Taraxacum officinale honey volatiles. Natural Product Communications, 10(2), 1934578X1501000. https://doi.org/10.1177/1934578x1501000238
• Jovin, E., Simin, N., Orčić, D., Balog, K., Beara, I., Lesjak, M., & Dukic, N. M. (2011). Antioxidant and anti-inflammatory properties of Rumex patientia L. Planta Medica, 77(12). https://doi.org/10.1055/s-0031-1282915
• Jürgens, A., Witt, T., & Gottsberger, G. (2002). Flower scent composition in night-flowering Silene species (Caryophyllaceae). Biochemical Systematics and Ecology, 30(5), 383-397. https://doi.org/10.1016/S0305-1978(01)00106-5
• Kaplan, Ö. and Gökşen Tosun, N. (2023). Biosynthesis of iron, copper and silver nanoparticles using polygonum cognatum and tragopogon porrifolius extracts and evaluation of their antimicrobial potentials. Duzce University Science and Technology Journal, 11(4), 2155-2167. https://doi.org/10.29130/dubited.1093468
• Karioti, A., Milošević-Ifantis, T., Pachopos, N., Niryiannaki, N., Hadjipavlou‐Litina, D., & Skaltsa, H. (2014). Antioxidant, anti-inflammatory potential and chemical constituents of Origanum dubium Boiss., growing wild in Cyprus. Journal of Enzyme Inhibition and Medicinal Chemistry, 30(1), 38-43. https://doi.org/10.3109/14756366.2013.871008
• Kaya, E., Akbaş, P., Ceyhan, G., Erdem, T. K., & Alkan, H. (2020). Determination the fatty acid composition of the rumex patientia l. leaves and in vitro antimicrobial activity of their different extracts. Suleyman Demirel University Science Institute Journal, 24(2), 362-367. https://doi.org/10.19113/sdufenbed.643154
• Kenny, O., Brunton, N. P., Walsh, D., Hewage, C. M., McLoughlin, P., & Smyth, T. J. (2015). Characterisation of antimicrobial extracts from dandelion root (Taraxacum officinale) using LC‐SPE‐NMR. Phytotherapy Research, 29(4), 526-532. https://doi.org/10.1002/ptr.5276
• Keyrouz, E., Feghali, P. A. R. E., Jaafar, M., & Nawas, T. (2017). Malva neglecta: a natural inhibitor of bacterial growth and biofilm formation. Journal of Medicinal Plants Research, 11(24), 380-386. https://doi.org/10.5897/jmpr2017.6422
• Khan, A. S., Arif, K., Munir, B., Kiran, S., Jalal, F., Qureshi, N. A., Hassan, S.M., Soomro, G.A., Nazir, A., Ghaffar, A., Tahir, M. A. & Iqbal, M. (2018). Estimating total phenolics in Taraxacum officinale (L.) extracts. Polish Journal of Environmental Studies, 28(1), 497-501. https://doi.org/10.15244/pjoes/78435
• Kim, K. H., Lee, K. H., Choi, S. U., Kim, Y. H., & Lee, K. R. (2008). Terpene and phenolic constituents of Lactuca indica L. Archives of Pharmacal Research, 31, 983-988. https://doi.org/10.1007/s12272-001-1256-8
• Kim, J., Lee, H., Choi, J., & Lee, S. (2022). Phytochemical constituents of Lactuca serriola leaves and their content analysis by HPLC-UV. Journal of Applied Biological Chemistry, 65(3), 153-158. https://doi.org/10.3839/jabc.2022.020
• Kiyama, R. (2017). Estrogenic terpenes and terpenoids: Pathways, functions and applications. European Journal of Pharmacology, 815, 405-415. https://doi.org/10.1016/j.ejphar.2017.09.049
• Küpeli, E., Orhan, İ. E., & Yeşilada, E. (2007). Evaluation of some plants used in Turkish folk medicine for their anti-inflammatory and antinociceptive activities. Pharmaceutical Biology, 45(7), 547-555. https://doi.org/10.1080/13880200701498895
• Lackus, N. D., Lackner, S., Gershenzon, J., Unsicker, S. B., & Köllner, T. G. (2018). The occurrence and formation of monoterpenes in herbivore-damaged poplar roots. Scientific Reports, 8(1). https://doi.org/10.1038/s41598-018-36302-6
• Lendzion, K., Gornowicz, A., Bielawski, K., & Bielawska, A. (2021). Phytochemical composition and biological activities of Scorzonera species. International Journal of Molecular Sciences, 22(10), 5128. https://doi.org/10.3390/ijms22105128
• Leyo, I. H., Ousmane, Z. M., Nomaou, D. L., Guimbo, I. D., Salaou, I. A., Francis, F., & Megido, R. C. (2022). Effect of maggot production residue on amaranth growth parameters. Open Journal of Soil Science, 12(12), 571-585. https://doi.org/10.4236/ojss.2022.1212024
• Li, X. and Yang, P. (2018). Research progress of Sonchus species. International Journal of Food Properties, 21(1), 147-157. https://doi.org/10.1080/10942912.2017.1415931
• Liu, R. H. (2013). Dietary bioactive compounds and their health implications. Journal of Food Science, 78(s1). https://doi.org/10.1111/1750-3841.12101
• Ma, L., Song, J., Shi, Y., Wang, C., Chen, B., Xie, D., & Jia, X. (2012). Anti-hepatitis b virus activity of chickweed [Stellaria media (L.) Vill.] extracts in HEPG2.2.15 cells. Molecules, 17(7), 8633-8646. https://doi.org/10.3390/molecules17078633
• Maletha, D., Singh, S. P., & Ramanarayanan, S. (2022). Hepatoprotective and nephroprotective efficacy of Cichorium intybus following imidacloprid induced subchronic toxicity in wlh cockerels. The Indian Journal of Animal Sciences, 92(8), 940-945. https://doi.org/10.56093/ijans.v92i8.123891
• Mamadalieva, N. Z., Lafont, R., & Wink, M. (2014). Diversity of secondary metabolites in the genus Silene L. (caryophyllaceae)—structures, distribution, and biological properties. Diversity, 6(3), 415-499. https://doi.org/10.3390/d6030415
• Maruyama, T., Ito, M., Kiuchi, F., & Honda, G. (2001). Molecular cloning, functional expression and characterization of d-limonene synthase from Schizonepeta tenuifolia. Biological and Pharmaceutical Bulletin, 24(4), 373-377. https://doi.org/10.1248/bpb.24.373
• Meinert, L., Frøst, M., Bejerholm, C., & Aaslyng, M. D. (2011). Enhancing the sensory quality of vegetables by decreasing some less-desired sensory properties with low-fat pork gravy. Journal of Culinary Science & Technology, 9(2), 113-131. https://doi.org/10.1080/15428052.2011.584496
• Mewalal, R., Rai, D. K., Kainer, D., Chen, F., Külheim, C., Peter, G. F., & Tuskan, G. A. (2017). Plant-derived terpenes: A feedstock for specialty biofuels. Trends in Biotechnology, 35(3), 227-240. https://doi.org/10.1016/j.tibtech.2016.08.003
• Miguel, M. G. (2010). Antioxidant and anti-inflammatory activities of essential oils: a short review. Molecules, 15(12), 9252-9287. https://doi.org/10.3390/molecules15129252
• Mohammed, F. S., Uysal, I., Yaz, H. H., & Sevindik, M. (2023). Papaver species: usage areas, essential oil, nutrient and elements contents, biological activities. Prospects in Pharmaceutical Sciences, 21(4), 1-9. https://doi.org/10.56782/pps.142
• Mohammadhosseini, M. (2021). Chemical composition of the essential oils from the aerial parts of Malva neglecta Wallr. from Khorramabad, Lorestan Province, Iran using solvent free microwave extraction (SFME) method. Trends in Phytochemical Research, 5(3), 155-163. https://doi.org/10.30495/tpr.2021.685071
• Monteiro, J. A., Júnior, J. M., Oliveira, I. R. N. d., Batista, F. L. A., Pinto, C. C. C., Silva, A. A. S., Morais, S.M. & Silva, M. G. V. (2018). Bioactivity and toxicity of Senna cana and Senna pendula extracts. Biochemistry Research International, 2018, 1-10. https://doi.org/10.1155/2018/8074306
• Muthukumaran, P., Kumaravel, S., & Nimia, N. (2019). Phytochemical, GC-MS and FT-IR analysis of Papaver somniferum L. Journal of Pharmaceutical and Biological Sciences, 7(1), 1-8. https://doi.org/10.18231/j.jpbs.2019.001
• Nasimi Doost Azgomi, R., Karimi, A., Tutunchi, H., & Moini Jazani, A. (2021). A comprehensive mechanistic and therapeutic insight into the effect of chicory (Cichorium intybus) supplementation in diabetes mellitus: A systematic review of literature. International Journal of Clinical Practice, 75(12), e14945. https://doi.org/10.1111/ijcp.14945
• Nouidha, S., Selmi, S., Guigonis, J., Pourcher, T., Chekir‐Ghedira, L., & Kilani‐Jaziri, S. (2023). Metabolomics profiling of Tunisian Sonchus oleraceus L. extracts and their antioxidant activities. Chemistry &Amp; Biodiversity, 20(8). https://doi.org/10.1002/cbdv.202300290
• Page, P., Favre, A., Schiestl, F. P., & Karrenberg, S. (2014). Do flower color and floral scent of Silene species affect host preference of Hadena bicruris, a seed-eating pollinator, under field conditions? PLoS ONE, 9(6), e98755. https://doi.org/10.1371/journal.pone.0098755
• Pearson, N., Ball, K., & Crawford, D. (2010). Predictors of changes in adolescents' consumption of fruits, vegetables and energy-dense snacks. British Journal of Nutrition, 105(5), 795-803. https://doi.org/10.1017/s0007114510004290
• Power, S., O’Toole, P. W., O’Connor, E. M., & Fitzgerald, G. F. (2011). Consumption of fruit and vegetables among elderly Irish people in long-term institutionalised care: the ELDERMET project. Proceedings of the Nutrition Society, 70(OCE3). https://doi.org/10.1017/s002966511100156x
• Quintana-Rodríguez, E., Morales-Vargas, A. T., Molina‐Torres, J., Adame-Álvarez, R. M., Acosta-Gallegos, J. A., & Heil, M. (2014). Plant volatiles cause direct, induced and associational resistance in common bean to the fungal pathogen Colletotrichum lindemuthianum. Journal of Ecology, 103(1), 250-260. https://doi.org/10.1111/1365-2745.12340
• Ramseier, D., Connolly, J., & Bazzaz, F. A. (2005). Carbon dioxide regime, species identity and influence of species initial abundance as determinants of change in stand biomass composition in five-species communities: an investigation using a simplex design and RGRD analysis. Journal of Ecology, 93(3), 502-511. https://doi.org/10.1111/j.1365-2745.2005.00999.x
• Ren, F., Zhang, Y., Qin, Y., Shang, J., Wang, Y., Wei, P., Guo, J., Jia, H. & Zhao, T. (2022). Taraxasterol prompted the anti-tumor effect in mice burden hepatocellular carcinoma by regulating t lymphocytes. Cell Death Discovery, 8(1). https://doi.org/10.1038/s41420-022-01059-5
• Riu-Aumatell, M., Vargas, L., Vichi, S., Guadayol, J. M., López-Tamames, E., & Buxaderas, S. (2011). Characterisation of volatile composition of white salsify (Tragopogon porrifolius L.) by Headspace Solid-Phase Microextraction (HS-SPME) and Simultaneous Distillation–Extraction (SDE) coupled to GC–MS. Food Chemistry, 129(2), 557-564. https://doi.org/10.1016/j.foodchem.2011.04.061
• Rufino, A. T., Ribeiro, M., Sousa, C., Judas, F., Salgueiro, L., Cavaleiro, C., & Mendes, A. F. (2015). Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis. European Journal of Pharmacology, 750, 141-150. https://doi.org/10.1016/j.ejphar.2015.01.018
• Sakul, A. A., Kurtul, E., Özbek, H., Kırmızı, N. İ., Bahtiyar, B. C., Saltan, H., & Açıkara, Ö. B. (2021). Evaluation of antidiabetic activities of Scorzonera species on alloxan induced diabetic mice. Clinical and Experimental Health Sciences, 11(1), 74-80. https://doi.org/10.33808/clinexphealthsci.797747
• Saleem, U., Khalid, S., Zaib, S., Anwar, F., Ahmad, B., Ullah, I., Zeb, A. & Ayaz, M. (2020). Phytochemical analysis and wound healing studies on ethnomedicinally important plant Malva neglecta Wallr. Journal of Ethnopharmacology, 249, 112401. https://doi.org/10.1016/j.jep.2019.112401
• Sánchez-Aguirre, O. A., Sánchez-Medina, A., Juárez-Aguilar, E., Barreda-Castillo, J. M., & Cano-Asseleih, L. M. (2024). Sonchus oleraceus L.: ethnomedical, phytochemical and pharmacological aspects. Naunyn-Schmiedeberg's Archives of Pharmacology, 397, 4555–4578. https://doi.org/10.1007/s00210-024-02966-3
• Siegmund, B., Urdl, K., Jurek, A., & Leitner, E. (2017). “More than Honey”: Investigation on volatiles from monovarietal honeys using new analytical and sensory approaches. Journal of Agricultural and Food Chemistry, 66(10), 2432-2442. https://doi.org/10.1021/acs.jafc.6b05009
• Suleimen, E. M., Sissengaliyeva, G. G., Ishmuratova, M. Y., & Jalmakhanbetova, R. I. (2019). The component composition of the tragopogon orientalis volatile constituents and its biological activity. Chemistry of Plant Raw Material, (3), 103-108. https://doi.org/10.14258/jcprm.2019034859
• Tang, Y. J., Park, H., Scher, H. B., & Jeoh, T. (2022). The role of a moisture-barrier latex in controlling retention, stability and release of d-limonene from complex coacervated matrix microparticles formed during spray drying. Frontiers in Nutrition, 9, 1-12, 979656. https://doi.org/10.3389/fnut.2022.979656
• Taskin, T., & Bitis, L. (2013). Antioxidant activity of Silene alba subsp. divaricata and Stellaria media subsp. media from Caryophyllaceae. Spatula DD-Peer Reviewed Journal on Complementary Medicine and Drug Discovery, 3(1), 1-5.
• Theis, N., & Lerdau, M. (2003). The evolution of function in plant secondary metabolites. International Journal of Plant Sciences, 164(S3), S93-S102. https://doi.org/10.1086/374190
• Ullah, F., Ayaz, A., Saqib, S., Zaman, W., Butt, M. A., & Ullah, A. (2019). Silene conoidea L.: a review on its systematic, ethnobotany and phytochemical profile. Plant Science Today, 6(4), 373-382. https://doi.org/10.14719/pst.2019.6.4.571
• Unlu, H. O., Unlu, H., & Karakurt, Y. (2017). The minerals and phenolic compositions of some edible wild plants consumed as vegetables. Fresenius Environmental Bulletin, 26(11), 6841-6847.
• Unver, T., Uzuner, U., Celik-Uzuner, S., Gurhan, I., Sivri, N. S., & Ozdemir, Z. (2023). Phytochemical composition, antimicrobial, anticancer properties and molecular docking profiles of Tragopogon coelesyriacus Boiss. extracts. Research Square,1, 1-33. https://doi.org/10.21203/rs.3.rs-3429191/v1
• Vivaldo, G., Masi, E., Taiti, C., Caldarelli, G., & Mancuso, S. (2017). The network of plants volatile organic compounds. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-10975-x
• Xu, L., Wang, J., Tian, A., Wang, S., Zhao, K., Rao, Z., Wu, X., Liu, Y., Liu, X., Chen, K., Li, X., Karrar, E., Gao, P., Ying, X., Xiao, G., & Ma, L. (2023). Characteristic volatiles fingerprints in olive vegetable stored at different conditions by HS-GC-IMS. Food Chemistry: X, 18, 100707. https://doi.org/10.1016/j.fochx.2023.100707
• Yang, Y. J., Yao, J., Jin, X. J., Shi, Z. N., Shen, T. F., Fang, J. G., Yao, X.J., & Zhu, Y. (2016). Sesquiterpenoids and tirucallane triterpenoids from the roots of Scorzonera divaricata. Phytochemistry, 124, 86-98. https://doi.org/10.1016/j.phytochem.2016.01.015
• Yeşil, Y., Çelik, M., & Yılmaz, B. (2019). Wild edible plants in Yeşilli (Mardin-Turkey), a multicultural area. Journal of Ethnobiology and Ethnomedicine, 15(1). https://doi.org/10.1186/s13002-019-0327-y
• Yıldırım, A. O., Mavi, A., & Kara, A. (2002). Antioxidant and antimicrobial activities of Polygonum cognatum Meissn extracts. Journal of the Science of Food and Agriculture, 83(1), 64-69. https://doi.org/10.1002/jsfa.1288
• Yılmazer, M., Karagöz, S. G., Ozkan, G., & Karacabey, E. (2016). Aroma transition from rosemary leaves during aromatization of olive oil. Journal of Food and Drug Analysis, 24(2), 299-304. https://doi.org/10.1016/j.jfda.2015.11.002
• Zengin, G., Mahomoodally, M. F., Ceylan, R., Uysal, Ş., Mocan, A., Yılmaz, M. A., Picot-Allain C.M.N, Ćirić A., Glamočlija, J. & Sokóvić, M. (2018). Functional constituents of six wild edible silene species: a focus on their phytochemical profiles and bioactive properties. Food Bioscience, 23, 75-82. https://doi.org/10.1016/j.fbio.2018.03.010
• Zhang, N., Chen, T., Ye, S., Gao, S., & Dong, Y. (2022). Comparative analysis with GC–MS of fatty acids and volatile compounds of Taraxacum kok-saghyz Rodin and Taraxacum officinale as edible resource plants. Separations, 9(10), 314. https://doi.org/10.3390/separations9100314
• Zhao, Y. and Kang, L. (2002). Role of plant volatiles in host plant location of the leafminer, Liriomyza sativae (diptera: agromyzidae). Physiological Entomology, 27(2), 103-111. https://doi.org/10.1046/j.1365-3032.2002.00275.x
• Zulaikha, S. (2015). Hazardous ingredients in cosmetics and personal care products and health concern: A review. Journal of Public Health Research, 5, 7-15.
• Zulak, K. G., & Bohlmann, J. (2010). Terpenoid biosynthesis and specialized vascular cells of conifer defense. Journal of Integrative Plant Biology, 52(1), 86-97. https://doi.org/10.1111/j.1744-7909.2010.00910.x