Evaluation of Individual Dependence and Reproducibility of Central Corneal Thickness Measurements with Anterior Segment Optical Coherence Tomography

Yıl 2022, , 10 - 13, 15.01.2022

Fatih Çelik , Pamuk Betül Ulucan

https://doi.org/10.16899/jcm.997505

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Abstract
Aim: To compare corneal thickness measurements made at different times and to evaluate their dependence on individuals.
Materials and Methods: The central corneal thickness of the right eyes of 30 healthy young adults was measured by the first investigator at three different times by the Anterior Segment Optical Coherence Tomography (AS-OCT) method. In addition, the fourth measurements were made by the second researcher at a different time. The obtained values were compared.
Results: The mean age was 29.8 ± 9.1 years. The mean CCT was 561.90 ± 37.6 µ in the first measurement, 562.20 ± 37.9 µ in the second measurement, and 562.80 ± 37.7 µ in the third measurement. In the measurement of CCT by the second investigator, the mean was 562.20 ± 38.0 µ. In statistical analysis, no significant difference was found between CCT values performed at different times (p<0.05). In addition, when the first measurement of the first researcher was compared with the first measurement of the second researcher, no significant difference was found between the CCT values of the two researchers (p<0.05).
Conclusion: Canon HS-100 AS-OCT device had very good reproducibility in the evaluation of CCT. There was no significant difference between the shots of different people. The use of OCT in daily practice is beneficial because it is both a non-contact method and has very good reproducibility in daily practice.
Keywords: Central corneal thickness, reproducibility, measurement

Anahtar Kelimeler

Central corneal thickness, reproducibility, measurement

Ön Segment Optik Koherens Tomografi ile Merkezi Kornea Kalınlığı Ölçümlerinin Bireysel Bağımlılık ve Tekrarlanabilirliğinin Değerlendirilmesi

Öz

Öz
Amaç: Farklı zamanlarda yapılan kornea kalınlığı ölçümlerini karşılaştırmak ve kişilere bağımlılığını değerlendirmek.
Gereç ve Yöntem: 30 sağlıklı genç erişkinin sağ gözlerinin santral korneal kalınlığı Anterior Segment Optical Coherence Tomography (AS-OCT) yöntemi ile birinci araştırmacı tarafından üç ayrı zamanda ölçüldü. Ayrıca ikinci araştırmacı tarafından dördüncü ölçümleri farklı bir zamanda yapıldı. Elde edilen değerler karşılaştırıldı.
Bulgular: Yaş ortalaması 29.8 ± 9.1 idi. Ortalama SKK birinci ölçümde 561.90 ± 37.6 µ, ikinci ölçümde 562.20 ± 37.9 µ, üçüncü ölçümde 562.80 ± 37.7 µ idi. SKK’ nın 2. araştırmacı tarafından ölçümünde ise ortalama 562.20 ± 38.0 µ idi. İstatistiksel analizde farklı zamanlarda yapılan SKK değerleri arasında anlamlı fark bulunamamıştır (p<0.05). Ayrıca birinci araştırmacının ilk ölçümüyle, ikinci araştırmacının ilk ölçümü karşılaştırıldığında, iki araştırmacı arasındaki SKK değerleri arasında anlamlı fark bulunmadı (p<0.05).
Sonuç: Canon HS-100 AS-OCT cihazının SKK değerlendirilmesinde tekrarlanabilirliğinin çok iyi olduğu görüldü. Farklı kişilerin çekimleri arasında anlamlı bir farklılık görülmedi. Günlük pratikte hem non-kontakt bir yöntem olduğu, hem de tekrarlanabilirliği çok iyi olduğu için OCT’ nin günlük pratikte kullanılması faydalıdır.
Anahtar Kelimeler: Santral korneal kalınlık, tekrarlanabilirlik, ölçüm

Anahtar Kelimeler

Santral korneal kalınlık, tekrarlanabilirlik, ölçüm

Kaynakça

• 1. Wang Z, Chen J, Yang B. Posterior corneal surface topographic changes after laser in situ keratomileusis are related to residual corneal bed thickness. Ophthalmology 1999;106(2):406-9; discussion 9-10.
• 2. Ucakhan OO, Ozkan M, Kanpolat A. Corneal thickness measurements in normal and keratoconic eyes: Pentacam comprehensive eye scanner versus noncontact specular microscopy and ultrasound pachymetry. Journal of cataract and refractive surgery 2006;32(6):970-7.
• 3. Holden BA, Mertz GW, McNally JJ. Corneal swelling response to contact lenses worn under extended wear conditions. Investigative ophthalmology & visual science 1983;24(2):218-26.
• 4. Auffarth GU, Wang L, Volcker HE. Keratoconus evaluation using the Orbscan Topography System. Journal of cataract and refractive surgery 2000;26(2):222-8.
• 5. Barkana Y, Gerber Y, Elbaz U, Schwartz S, Ken-Dror G, Avni I, et al. Central corneal thickness measurement with the Pentacam Scheimpflug system, optical low-coherence reflectometry pachymeter, and ultrasound pachymetry. Journal of cataract and refractive surgery 2005;31(9):1729-35.
• 6. Swarbrick HA, Wong G, O'Leary DJ. Corneal response to orthokeratology. Optometry and vision science : official publication of the American Academy of Optometry 1998;75(11):791-9.
• 7. Kawana K, Tokunaga T, Miyata K, Okamoto F, Kiuchi T, Oshika T. Comparison of corneal thickness measurements using Orbscan II, non-contact specular microscopy, and ultrasonic pachymetry in eyes after laser in situ keratomileusis. The British journal of ophthalmology 2004;88(4):466-8.
• 8. Piotrowiak I, Soldanska B, Burduk M, Kaluzny BJ, Kaluzny J. Measuring Corneal Thickness with SOCT, the Scheimpflug System, and Ultrasound Pachymetry. ISRN ophthalmology 2012;2012:869319.
• 9. Coskunseven E, Jankov MR, 2nd, Hafezi F. Contralateral eye study of corneal collagen cross-linking with riboflavin and UVA irradiation in patients with keratoconus. Journal of refractive surgery (Thorofare, NJ : 1995) 2009;25(4):371-6.
• 10. Muallem MS, Yoo SH, Romano AC, Marangon FB, Schiffman JC, Culbertson WW. Flap and stromal bed thickness in laser in situ keratomileusis enhancement. Journal of cataract and refractive surgery 2004;30(11):2295-302.
• 11. Randleman JB, Woodward M, Lynn MJ, Stulting RD. Risk assessment for ectasia after corneal refractive surgery. Ophthalmology 2008;115(1):37-50.
• 12. Kosker M, Calıskan S, Celikay O, Dogan AS, Kaya A, Gurdal C. Assesment of Central Corneal Thickness Using Corneal Dynamic Scheimpflug Analyzer Corvis ST, Sirius Kombine Scheimpflug-Placido Disk System and RTVue Anterior Segment Optical Coherence Tomography in Normal Eyes. Van Medical Journal 2018;25(3):381-385.
• 13. Li Y, Tang M, Zhang X, Salaroli CH, Ramos JL, Huang D. Pachymetric mapping with Fourier-domain optical coherence tomography. Journal of cataract and refractive surgery. 2010;36(5):826-31.
• 14. Leung DY, Lam DK, Yeung BY, Lam DS. Comparison between central corneal thickness measurements by ultrasound pachymetry and optical coherence tomography. Clinical & experimental ophthalmology. 2006;34(8):751-4.
• 15. Grewal DS, Brar GS, Grewal SP. Assessment of central corneal thickness in normal, keratoconus, and post-laser in situ keratomileusis eyes using Scheimpflug imaging, spectral domain optical coherence tomography, and ultrasound pachymetry. Journal of cataract and refractive surgery. 2010;36(6):954-64.
• 16. Fishman GR, Pons ME, Seedor JA, Liebmann JM, Ritch R. Assessment of central corneal thickness using optical coherence tomography. Journal of cataract and refractive surgery. 2005;31(4):707-11.