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Kronik migren tanılı bireylerde fiziksel aktivite düzeyi, ağrı özellikleri, katastrofizasyonu, santral sensitizasyon ve fonksiyonel durum parametrelerinin araştırılması- kesitsel çalışma

Yıl 2025, Cilt: 12 Sayı: 1, 11 - 20, 29.03.2025
https://doi.org/10.15437/jetr.1512212

Öz

Amaç: Bu çalışmanın amacı, kronik migren tanılı bireylerde fiziksel aktivite (FA) düzeyi ile ağrı özellikleri ve katastrofizasyonu, santral sensitizasyon ve fonksiyonel durum arasındaki ilişkiyi incelemekti.
Yöntem: Çalışmaya kronik migren tanısı alan 116 birey [yaş: 33,00 (19,00-55,00) yıl] dahil edildi. Fiziksel ve sosyodemografik özellikler, migren ile ilgili klinik bilgiler kaydedildi. Ağrı özellikleri kapsamında ağrı şiddeti ve ağrı süresi kaydedildi. FA düzeyi “Uluslararası Fiziksel Aktivite Anketi-Kısa Formu” ile, ağrı katastrofizasyonu “Ağrıyı Felaketleştirme Ölçeği” ile, santral sensitizasyon “Santral Sensitizasyon Ölçeği” ile, ve fonksiyonel durum “Migrene Bağlı Dizabilite Değerlendirme Ölçeği” ile değerlendirildi.
Bulgular: Bireylerin %30,20’sinin (n=35) inaktif, %47,40’ının (n=55) minimal aktif ve 22,40’ının (n=26) aktif olduğu görüldü. FA düzeyi ile ağrı şiddeti (r=-0,245, p=0,008), ağrı süresi (r=-0,208, p=0,025) ve ağrı katastrofizasyonu (r=-0,190, p=0,041) arasında negatif yönde zayıf bir ilişki bulunurken, FA düzeyi ile santral sensitizasyon (r=-0,198, p=0,033) arasında çok zayıf bir ilişki bulundu. FA düzeyi ile fonksiyonel durum arasında ilişki olmadığı saptandı (p>0,05).
Sonuç: Çalışmanın sonucunda kronik migren tanılı bireylerin FA düzeyi arttıkça ağrı şiddeti, süresi, katastrofizasyonu ve santral sensitizasyonun azaldığı görüldü. Ayrıca FA düzeyi ile fonksiyonel durum arasında ilişki olmadığı bulundu. Düzenli FA’nın faydaları göz önünde bulundurulduğunda kliniklerde bu bireylere özgü FA programlarının oluşturulması teşvik edilmelidir.

Kaynakça

  • Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38:1-211.
  • Lipton RB, Bigal ME, Diamond M, et al. Migraine prevalence, disease burden, and the need for preventive therapy. Neurology. 2007;68:343-349.
  • Caspersen CJ, Powell KE, Christenson GM. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep. 1985;100:126-131.
  • Amin FM, Aristeidou S, Baraldi C, et al. The association between migraine and physical exercise. J Headache Pain. 2018;19:1-9.
  • Pellegrino ABW, Davis-Martin RE, Houle TT, et al. Perceived triggers of primary headache disorders: A meta-analysis. Cephalalgia. 2018;38:1188-1198.
  • La Touche R, Fernandez Perez JJ, Proy Acosta A, et al. Is aerobic exercise helpful in patients with migraine? A systematic review and meta‐analysis. Scand J Med Sci Sports. 2020;30:965-982.
  • Edwards RR. Individual differences in endogenous pain modulation as a risk factor for chronic pain. Neurology. 2005;65:437-443.
  • Elfving B, Andersson T, Grooten WJ. Low levels of physical activity in back pain patients are associated with high levels of fear-avoidance beliefs and pain catastrophizing. Physiother Res Int. 2007;12:14-24.
  • Malfliet A, Kregel J, Cagnie B, et al. Lack of evidence for central sensitization in idiopathic, non-traumatic neck pain: a systematic review. Pain Physician. 2015;18:223-236.
  • Harte SE, Harris RE, Clauw DJ. The neurobiology of central sensitization. J Appl Biobehav Res. 2018;23:e12137.
  • Moriki K, Tushima E, Ogihara H, et al. Combined effects of lifestyle and psychosocial factors on central sensitization in patients with chronic low back pain: A cross-sectional study. J Orthop Sci. 2022;27:1185-1189.
  • Domingues RB, Teixeira AL, Domingues SA. Physical practice is associated with less functional disability in medical students with migraine. Arq Neuro-psiquiat. 2011;69:39-43.
  • Altay H, Toprak Çelenay Ş. Migrenli bireylerin klinik özellikleri ve fiziksel aktivite ilişkisi. Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Derg. 2021;5:454-468.
  • Saglam M, Arikan H, Savci S, et al. International physical activity questionnaire: reliability and validity of the Turkish version. Percept Motor Skill. 2010;111:278-284.
  • Farrar JT, Young JP Jr, LaMoreaux L, et al. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain. 2001;94:149-158.
  • Ugurlu M, Karakas Ugurlu G, Erten S, et al. Validity of Turkish form of Pain Catastrophizing Scale and modeling of the relationship between pain-related disability with pain intensity, cognitive, and emotional factors. Psychiatry Clin Psychopharmacol. 2017;27:189-196.
  • Keleş ED, Birtane M, Ekuklu G, et al. Validity and reliability of the Turkish version of the central sensitization inventory. Arch Rheumatol. 2021;36:518.
  • Ertas M, Siva A, Dalkara T, et al. Validity and reliability of the Turkish Migraine Disability Assessment (MIDAS) questionnaire. Headache. 2004;44:786-793.
  • Dancey CP, Reidy J. Statistics Without Maths for Psychology. Pearson/Prentice Hall; 2007.
  • Hauge AW, Kirchmann M, Olesen J. Trigger factors in migraine with aura. Cephalalgia. 2010;30:346-353.
  • Busch V, Gaul C. Exercise in migraine therapy-is there any evidence for efficacy? A critical review. Headache. 2008;48:890-899.
  • Varkey E, Hagen K, Zwart JA, et al. Physical activity and headache: results from the Nord-Trondelag Health Study (HUNT). Cephalalgia. 2008;28:1292-1297.
  • Rogers DG, Protti TA, Smitherman TA. Fear, Avoidance, and Disability in Headache Disorders. Curr Pain Headache R. 2020;24:33.
  • Vlaeyen JWS, Linton SJ. Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. Pain. 2000;85:317-332.
  • Zhaoyang R, Martire LM, Darnall BD. Daily pain catastrophizing predicts less physical activity and more sedentary behavior in older adults with osteoarthritis. Pain. 2020;161:2603-2610.
  • Johnson MH. How does distraction work in the management of pain?. Curr Pain Headache R. 2005;9:90-95.
  • Puterman E, O'Donovan A, Adler NE, et al. Physical activity moderates effects of stressor-induced rumination on cortisol reactivity. Psychosom Med. 2011;73:604-611.
  • Nijs J, Ickmans K. Chronic whiplash-associated disorders: to exercise or not? Lancet. 2014;384:109-111.
  • Koltyn KF. Analgesia following exercise: a review. Sports Med. 2000;29:85-98.
  • Nijs J, Meeus M, Versijpt J, et al. Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target? Expert Opin Ther Tar. 2015;19:565-576.
  • Kalatakis-dos-Santos AE, Fidelis-de-Paula-Gomes CA, Bassi-Dibai D, et al. Correlation between habitual physical activity and central sensitization, pain intensity, kinesiophobia, catastrophizing, and the severity of myogenous temporomandibular disorder. J Chiropr Med. 2019;18:299-304.
  • Zheng X, Reneman MF, Preuper RHS, et al. Relationship between physical activity and central sensitization in chronic low back pain: Insights from machine learning. Comput Meth Prog Bio. 2023;232:107432.
  • Fillingim RB, King CD, Ribeiro-Dasilva MC, et al. Sex, gender, and pain: a review of recent clinical and experimental findings. J Pain. 2009;10:447-485.
  • Khan J, Asoom LIA, Sunni AA, et al. Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine. Biomed Pharmacother. 2021;139:111557.

Investigation of physical activity level, pain characteristics, catastrophizing, central sensitization, and functional status parameters in individuals diagnosed with chronic migraine-a cross-sectional study

Yıl 2025, Cilt: 12 Sayı: 1, 11 - 20, 29.03.2025
https://doi.org/10.15437/jetr.1512212

Öz

Purpose: The aim of this study was to investigate the relationship between physical activity (PA) level and pain characteristics and catastrophization, central sensitization, and functional status in individuals diagnosed with chronic migraine.
Methods: The study included 116 individuals diagnosed with chronic migraine [age: 33.00 (19.00-55.00) years]. Physical and sociodemographic characteristics, as well as clinical information about migraine, were recorded. Pain characteristics, including pain intensity and pain duration were recorded. PA level assessed with the "International Physical Activity Questionnaire-Short Form", pain catastrophization with the "Pain Catastrophizing Scale", central sensitization with the "Central Sensitization Scale", and functional status with the "Migraine Disability Assessment Scale".
Results: It was observed that 30.20% (n=35) of the individuals were inactive, 47.40% (n=55) were minimally active, and 22.40% (n=26) were active. A weak negative correlation was found between PA level and pain intensity (r=-0.245, p=0.008), pain duration (r=-0.208, p=0.025) and pain catastrophization (r=-0.190, p=0.041); and a very weak negative correlation with central sensitization (r=-0.198, p=0.033). There was no significant correlation between PA level and functional status (p>0.05).
Conclusion: As a result of the study, it was observed that as the PA level of individuals diagnosed with chronic migraine increased, pain intensity, duration, catastrophizing and central sensitization decreased. In addition, no relationship was observed between PA level and functional status. Given the benefits of regular PA, clinics should promote tailored PA programs for these individuals.

Kaynakça

  • Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38:1-211.
  • Lipton RB, Bigal ME, Diamond M, et al. Migraine prevalence, disease burden, and the need for preventive therapy. Neurology. 2007;68:343-349.
  • Caspersen CJ, Powell KE, Christenson GM. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep. 1985;100:126-131.
  • Amin FM, Aristeidou S, Baraldi C, et al. The association between migraine and physical exercise. J Headache Pain. 2018;19:1-9.
  • Pellegrino ABW, Davis-Martin RE, Houle TT, et al. Perceived triggers of primary headache disorders: A meta-analysis. Cephalalgia. 2018;38:1188-1198.
  • La Touche R, Fernandez Perez JJ, Proy Acosta A, et al. Is aerobic exercise helpful in patients with migraine? A systematic review and meta‐analysis. Scand J Med Sci Sports. 2020;30:965-982.
  • Edwards RR. Individual differences in endogenous pain modulation as a risk factor for chronic pain. Neurology. 2005;65:437-443.
  • Elfving B, Andersson T, Grooten WJ. Low levels of physical activity in back pain patients are associated with high levels of fear-avoidance beliefs and pain catastrophizing. Physiother Res Int. 2007;12:14-24.
  • Malfliet A, Kregel J, Cagnie B, et al. Lack of evidence for central sensitization in idiopathic, non-traumatic neck pain: a systematic review. Pain Physician. 2015;18:223-236.
  • Harte SE, Harris RE, Clauw DJ. The neurobiology of central sensitization. J Appl Biobehav Res. 2018;23:e12137.
  • Moriki K, Tushima E, Ogihara H, et al. Combined effects of lifestyle and psychosocial factors on central sensitization in patients with chronic low back pain: A cross-sectional study. J Orthop Sci. 2022;27:1185-1189.
  • Domingues RB, Teixeira AL, Domingues SA. Physical practice is associated with less functional disability in medical students with migraine. Arq Neuro-psiquiat. 2011;69:39-43.
  • Altay H, Toprak Çelenay Ş. Migrenli bireylerin klinik özellikleri ve fiziksel aktivite ilişkisi. Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Derg. 2021;5:454-468.
  • Saglam M, Arikan H, Savci S, et al. International physical activity questionnaire: reliability and validity of the Turkish version. Percept Motor Skill. 2010;111:278-284.
  • Farrar JT, Young JP Jr, LaMoreaux L, et al. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain. 2001;94:149-158.
  • Ugurlu M, Karakas Ugurlu G, Erten S, et al. Validity of Turkish form of Pain Catastrophizing Scale and modeling of the relationship between pain-related disability with pain intensity, cognitive, and emotional factors. Psychiatry Clin Psychopharmacol. 2017;27:189-196.
  • Keleş ED, Birtane M, Ekuklu G, et al. Validity and reliability of the Turkish version of the central sensitization inventory. Arch Rheumatol. 2021;36:518.
  • Ertas M, Siva A, Dalkara T, et al. Validity and reliability of the Turkish Migraine Disability Assessment (MIDAS) questionnaire. Headache. 2004;44:786-793.
  • Dancey CP, Reidy J. Statistics Without Maths for Psychology. Pearson/Prentice Hall; 2007.
  • Hauge AW, Kirchmann M, Olesen J. Trigger factors in migraine with aura. Cephalalgia. 2010;30:346-353.
  • Busch V, Gaul C. Exercise in migraine therapy-is there any evidence for efficacy? A critical review. Headache. 2008;48:890-899.
  • Varkey E, Hagen K, Zwart JA, et al. Physical activity and headache: results from the Nord-Trondelag Health Study (HUNT). Cephalalgia. 2008;28:1292-1297.
  • Rogers DG, Protti TA, Smitherman TA. Fear, Avoidance, and Disability in Headache Disorders. Curr Pain Headache R. 2020;24:33.
  • Vlaeyen JWS, Linton SJ. Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. Pain. 2000;85:317-332.
  • Zhaoyang R, Martire LM, Darnall BD. Daily pain catastrophizing predicts less physical activity and more sedentary behavior in older adults with osteoarthritis. Pain. 2020;161:2603-2610.
  • Johnson MH. How does distraction work in the management of pain?. Curr Pain Headache R. 2005;9:90-95.
  • Puterman E, O'Donovan A, Adler NE, et al. Physical activity moderates effects of stressor-induced rumination on cortisol reactivity. Psychosom Med. 2011;73:604-611.
  • Nijs J, Ickmans K. Chronic whiplash-associated disorders: to exercise or not? Lancet. 2014;384:109-111.
  • Koltyn KF. Analgesia following exercise: a review. Sports Med. 2000;29:85-98.
  • Nijs J, Meeus M, Versijpt J, et al. Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target? Expert Opin Ther Tar. 2015;19:565-576.
  • Kalatakis-dos-Santos AE, Fidelis-de-Paula-Gomes CA, Bassi-Dibai D, et al. Correlation between habitual physical activity and central sensitization, pain intensity, kinesiophobia, catastrophizing, and the severity of myogenous temporomandibular disorder. J Chiropr Med. 2019;18:299-304.
  • Zheng X, Reneman MF, Preuper RHS, et al. Relationship between physical activity and central sensitization in chronic low back pain: Insights from machine learning. Comput Meth Prog Bio. 2023;232:107432.
  • Fillingim RB, King CD, Ribeiro-Dasilva MC, et al. Sex, gender, and pain: a review of recent clinical and experimental findings. J Pain. 2009;10:447-485.
  • Khan J, Asoom LIA, Sunni AA, et al. Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine. Biomed Pharmacother. 2021;139:111557.
Toplam 34 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Fizyoterapi
Bölüm Makaleler
Yazarlar

Elif Sena Düşgün 0000-0003-0419-1150

Meliha Aydın 0009-0004-0617-3540

Selin Birgül Baran 0009-0004-0039-8175

Şeyda Toprak Çelenay 0000-0001-6720-4452

Yayımlanma Tarihi 29 Mart 2025
Gönderilme Tarihi 9 Temmuz 2024
Kabul Tarihi 6 Aralık 2024
Yayımlandığı Sayı Yıl 2025 Cilt: 12 Sayı: 1

Kaynak Göster

Vancouver Düşgün ES, Aydın M, Baran SB, Toprak Çelenay Ş. Kronik migren tanılı bireylerde fiziksel aktivite düzeyi, ağrı özellikleri, katastrofizasyonu, santral sensitizasyon ve fonksiyonel durum parametrelerinin araştırılması- kesitsel çalışma. JETR. 2025;12(1):11-20.