İnsan Mikrobiotası ve Jinekolojik Hastalıklara Olan Etkisi

Yıl 2019, Cilt: 16 Sayı: 4, 244 - 249, 31.12.2019

Ümit Yasemin Sert , Nuray Bozkurt

Öz

İnsan vücudu on binlerce mikroorganizmaya ev sahipliği yapar. Deri, ağız, vajina, gastro-intestinal sistem, üriner sistem, hatta yakın geçmişe kadar steril olduğu düşünülen plasenta ve akciğer çeşitli mikroorganizmaları barındırır. Geçtiğimiz 20 yılda, hastalıklara ve immün sistem restorasyonuna bakış açısını değiştiren iki önemli proje ortaya çıkmıştır: İnsan Genom Projesi (İGP, Human Genome Project-1990-2003) ve İnsan Mikrobiom Projesi (İMP, Human Microbiome Project-2008-2012). Bu çalışmaların da etkisi ile insan mikrobiotasının birçok hastalığın ortaya çıkışında önemli role sahip olduğu gösterilmiştir. Özellikle vajinal, gastro-intestinal ve üriner mikrobiotanın jinekolojik hastalıklar üzerinde önemli etkileri bulunmaktadır. Bu derleme insan mikrobiotasının jinekolojik hastalıkların oluşumu üzerine etkileri ve bu etkinin proflaksi, destek ve tedavi amaçlı nasıl kullanılabileceğini araştırmayı amaçlamaktadır.

Anahtar Kelimeler

İnsan Gen projesi, , Jinekolojik hastalık, Mikrobiota, Probiyotik

Kaynakça

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