Evaluation Of The Role Of Complete Blood Count Indices To Predict The Risk Of Pre-Eclampsia

Yıl 2016, Cilt: 13 Sayı: 3, 99 - 102, 01.07.2016

Keziban Doğan , Ali Yeşil , Bülent Babaoğlu Levent Yaşar

Öz

Aim: To compare the complete blood count CBC indices in the mild preeclamptic, severe preeclamptic and healthy normotensive pregnant women to evaluate whether these parameters have a predictive and prognostic significance in determining the risk and the severity of preeclampsia PE .Material and Methods: A retrospective case-control study was designed including the patient population n= 187 composed of 39 % 19.7 severe PE, 55 % 27.8 mildPE, 104 % 52.5 healthy normotensive singleton pregnant women for controls. The hematocrit Hct , hemoglobin Hb , leukocyte count, platelet count PC , mean platelet volume MPV , platelet distribution width PDW , PC/MPV ratio, systemic inflammatory markers including neutrophil/lymphocyte ratio NRL , platelet/lymphocyte ratio PRL , platelet/ neutrophil PRN ratio were recorded.Results: In comparison of the preeclamptic patients with controls; there was statistically significant difference in MPV p=0.012, p

Anahtar Kelimeler

Preeclampsia, CBC indices, MPV, PDW, PC/MPV ratio

Tam Kan Sayımı Parametrelerinin Pre-Eklampsi Riskini Öngörmedeki Rolünün Değerlendirilmesi

Öz

Amaç: Ağır preeklampsi, hafif preeklampsi ve sağlıklı gebelerde tam kan sayımı parametrelerini karşılaştırarak, bu parametrelerin preeklampsi tanısı ve şiddetini belirlemedeki önemini tespit etmeyi amaçladık.Gereç ve Yöntemler: Retrospektif vaka kontrollü olarak planlanan bu çalışmada; 39 % 19.7 u ağır preeklampsi, 55 % 27.8 i hafif preeklampsi ve 104 % 52.5 ü ise sağlıklı tekiz gebeden oluşan toplam 187 olgu çalışmaya dahil edildi. Hemoglobin Hb , hemotokrit Hct , trombosit sayısı, ortalama trombosit hacmi MPV , trombosit dağılım aralığı PDW , trombosit /MPV oranı, lökosit sayısı ile birlikte sistemik inflamatuar yanıt markırları olannötrofil/lenfosit NLO , trombosit/lenfosit TLO , trombosit /nötrofil TNO oranları kayıt altına alındı.Bulgular: Ağır ve hafif preeklampsi grupları arasında anlamlı farklılık tespit edilmezken, kontrol grubuyla karşılaştırıldığında, MPV preeklamptik grupta anlamlı derecede yüksek tespit edildi p=0.012, p

Anahtar Kelimeler

Preeklampsi, tam kan sayım parametreleri, MPV, PDW, trombosit/MPV

Kaynakça

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