CRYOPRESERVATION IN ASSISTED REPRODUCTION AND FERTILITY PRESERVATION

Yıl 2020, Cilt: 17 Sayı: 3, 492 - 496, 30.09.2020

İnci Kahyaoğlu , Gülnur Take

https://doi.org/10.38136/jgon.775326

Cited By: 4

Öz

Cryopreservation is the technique of keeping living cells or tissues at ultralow temperature that no metabolic or biochemical activity can ocur. The use of cryopreservation techniques is highly attractive and has been increasingly applied worldwide. Cryopreservation of sperm, oocytes and embryos have been central to improvements in the assisted reproduction treatment success with many potential applications. Embryo cryopreservation is an established procedure and has been increasingly used due to novel indications as freeze-all strategy to reduce complications of assisted reproduction as ovarian hyperstimulation syndrome, pre-implantation genetic screening or single embryo transfer and cryopreservation of the remaining embryos to minimize the risk of multiple pregnancies. Sperm and oocyte cryopreservation has permitted the longterm storage of gametes for patients with anticipated fertility decline. Ovarian and testicular tissue cryopreservation is the treatment options for prepubertal girls and boys requiring fertility preservation. Although they are relatively new techniques compared to gamete or embryo cryopreservation, they are both very promising and expected to be more widely implemented into the clinic in the near future.

Anahtar Kelimeler

Cryopreservation, Oocyte, Sperm, Embryo, Testis, Ovary

YARDIMCI ÜREME TEKNİKLERİ VE FERTİLİTE PREZERVASYONUNDA KRİYOPREZERVASON

Öz

Kriyoprezervasyon, canlı hücre veya dokuların metabolik ve biyokimyasal aktivitelerinin durdurulduğu çok düşük derecelerde saklanmasıdır. Kriyoprezervasyon teknikleri oldukça ilgi çekici olup dünya çapında gittikçe artan oranlarda kullanılmaktadır. Sperm, oosit ve embriyoların dondurularak saklanması, yardımcı üreme teknikleri tedavilerinde potansiyel birçok kullanım alanı bulmuş olup başarı artışında önemli rol oynamaktadır. Embriyo kriyoprezervasyonu, özellikle freze-all stratejisine olanak sağlayarak ovaryan hiperstimülasyon sendromu gibi yardımcı üreme teknikleri tedavi komplikasyonlarının önlenmesi, preimplantasyon genetik tanıya olanak sağlaması, tek embriyo transferi yapılıp diğer embriyoların saklanmasına olanak sağlayarak çoğul gebeliklerin önüne geçilebilmesi gibi pek çok nedenden ötürü her geçen gün kullanımı artan bir prosedür haline gelmiştir. Sperm ve oosit dondurulması ise fertilite kaybı ile yüz yüze kalan hastalar için uzun dönem kendi gamet hücrelerinin saklanabilmesine olanak sağlar. Over ve testis doku dondurulması ise prepubertal dönemdeki kız ve erkeklerde fertilite prezervasyonu için tek tedavi seçeneğidir. Diğerleri ile kıyaslandığında daha yeni teknikler olsalar da, gelecek vadeden ve yakın gelecekte kullanımının daha artacağı düşünülen tedavi seçenekleri olarak değerlendirilmektedirler.

Anahtar Kelimeler

Kriyoprezervasyon, Oosit, Sperm, Embryo, Testis, Over

Kaynakça

• 1. Wu B. Advances in Embryo Transfer . Chapter 16: Fertility Cryopreservation. Francesca Ciani, Natascia Cocchia, Luigi Esposito, Luigi Avallone. IntechOpen. 2012, p: 225-248.
• 2. Levi-Setti PE, Patrizio P, Scaravelli G. Evolution of human oocyte cryopreservation: slow freeziersus vitrification. Curr Opin Endocrinol Diabetes Obes. 2016;23(6):445-450.
• 3. Gook DA, Edgar DH. Cryopreservation of female reproductive potential. Best Pract Res Clin Obstet Gynaecol. 2019 Feb;55:23-36.
• 4. Rienzi LF, Iussig B, Dovere L, Fabozzi G, Cimadomo D, Ubaldi FM. Perspectives in Gamete and Embryo Cryopreservation. Semin Reprod Med. 2018;36(5):253-264.
• 5. Rodriguez-Wallberg KA , Waterstone M, Anastácio A . Ice age: Cryopreservation in assisted reproduction - An update. Reprod Biol. 2019;19(2):119-126.
• 6. Kevin Coward & Dagan Wells. Textbook of Clinical Embryology. Chapter 31: Cryopreservation in assisted reproduction, by Craig J& Turner K. Cambridge University Press, 2013, 327-336.
• 7. Ri-Cheng Chian& Patrick Quinn. Fertility Cryopreservation. Chapter 4 Cryoprotectants, Swain JE & Smith GD. Cambridge University Press, 2010. p: 24-38.
• 8. Jang TH, Park SC, Yang JH, Kim JY, Seok JH, Park US, Choi CW, Lee SR, Han J. Cryopreservation and its clinical applications. Integr Med Res. 2017 Mar;6(1):12-18.
• 9. Edgar DH, Gook DA. A critical appraisal of cryopreservation (slow cooling versus vitrification) of human oocytes and embryos. Hum Reprod Update 2012;18(05):536–554.
• 10. In-Vitro Fertilization: Third Edition , ed. Kay Elder and Brian Dale. Published by Cambridge University Press. 2011. pp: 191-215.
• 11. Rienzi L, Gracia C, Maggiulli R, LaBarbera AR, Kaser DJ, Ubaldi FM, Vanderpoel S, Racowsky C. Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance. Hum Reprod Update. 2017 Mar 1;23(2):139-155.
• 12. Jerome Strauss Robert Barbieri. Yen & Jaffe's Reproductive Endocrinology 8th Edition. Elsevier, 2018, pp: 823-856.
• 13. Principles of IVF Laboratory Practice, Optimizing Performance and Outcomes. Edited by Markus H. M. Montag, Dean E. Morbeck Chapter 20. Vitrification of Oocytes for IVF by Laura Rienzi, Benedetta Iussig, Filippo M. Ubaldi. Cambrige University Press, 2017, p:138-144.
• 14. Hezavehei M, Sharafi M, Kouchesfahani HM, Henkel R, Agarwal A, Esmaeili V, Shahverdi A. Sperm cryopreservation: A review on current molecular cryobiology and advanced approaches. Reprod Biomed Online. 2018;37(3):327-339.
• 15. Martinez F; on behalf of the International Society for Fertility Preservation-ESHRE-ASRM Expert Working Group. Update on fertility preservation from the Barcelona International Society for Fertility Preservation-ESHRE-ASRM 2015 expert meeting: indications, results and future perspectives. Hum Reprod 2017; 32(09):1802–1811.
• 16. Kopeika J, Thornhill A, Khalaf Y. The effect of cryopreservation on the genome of gametes and embryos: principles of cryobiology and critical appraisal of the evidence. Hum Reprod Update 2015; 21(02):209–227.
• 17. Borges E Jr, Rossi LM, Locambo de Freitas CV, et al. Fertilization and pregnancy outcome after intracytoplasmic injection with fresh or cryopreserved ejaculated spermatozoa. Fertil Steril 2007;87(02):316–320.
• 18. Ohlander S, Hotaling J, Kirshenbaum E, Niederberger C, Eisenberg ML. Impact of fresh versus cryopreserved testicular sperm upon intracytoplasmic sperm injection pregnancy outcomes in men with azoospermia due to spermatogenic dysfunction: a meta-analysis. Fertil Steril 2014;101:344–9.
• 19. Kilcoyne KR, Mitchell RT.FERTILITY PRESERVATION: Testicular transplantation for fertility preservation: clinical potential and current challenges. Reproduction. 2019 Nov;158(5):F1-F14.
• 20. Onofre J, Baert Y, Faes K & Goossens E. Cryopreservation of testicular tissue or testicular cell suspensions: a pivotal step in fertility preservation. Human Reproduction Update. 2016 22 744–761.
• 21. Zarandi NP, Galdon G, Kogan S, Atala A, Sadri-Ardekani H. Cryostorage of immature and mature human testis tissue to preserve spermatogonial stem cells (SSCs): a systematic review of current experiences toward clinical applications. Stem Cells Cloning.2018;11: 23–38.
• 22. Argyle CE, Harper JC, Davies MC. Oocyte cryopreservation: where are we now? Hum Reprod Update. 2016;22(4):440-9.
• 23. Saragusty J, Arav A. Current progress in oocyte and embryo cryopreservation by slow freezing and vitrification. Reproduction 2011;141:1 – 19.
• 24. Cobo A, Diaz C. Clinical application of oocyte vitrification: a systematic review and meta-analysis of randomized controlled trials. Fertil Steril. 2011;96:277–285.
• 25. American Society for Reproductive Medicine, Society for Assisted Reproductive Technology. Mature oocyte cryopreservation: a guideline. Fertil Steril. 2013;99:37 – 43
• 26. Amorim CA, Leonel ECR, Afifi Y, Coomarasamy A, Fishel S. Cryostorage and retransplantation of ovarian tissue as an infertility treatment. Best Pract Res Clin Endocrinol Metab. 2019;33(1):89-102.
• 27. Leonel ECR, Corral A, Risco R, Camboni A, Taboga SR, Kilbride P, Vazquez M, Morris J, Dolmans MM, Amorim CA. Stepped vitrification technique for human ovarian tissue cryopreservation. Sci Rep. 2019;27;9(1):20008.
• 28. Suzuki N, Yoshioka N, Takae S, Sugishita Y, Tamura M, Hashimoto S, et al. Successful fertility preservation following ovarian tissue vitrification in patients with primary ovarian insufficiency. Hum Reprod 2015;30:608e15.
• 29. Pacheco F, Oktay K. Current success and efficiency of autologous ovarian transplantation: a meta-analysis. Reprod Sci. 2017;24: 1111–1120.
• 30. DeGeyterC,Calhaz-JorgeC,KupkaMS,WynsC,etal.ARTinEurope,2014:results generated from European registries by ESHRE: the European IVF-monitoring consortium (EIM) for the European society of human reproduction and embryology (ESHRE). Hum Reprod. 2018;33:1586–601.