RHABDOMYOSARCOMA IN A NEWBORN: CASE REPORT

Yıl 2021, Cilt: 18 Sayı: 4, 1099 - 1102, 31.12.2021

Aslı Genç , Mustafa Şenol Akın , Derya Özyörük , Sevim Ünal

https://doi.org/10.38136/jgon.943740

Öz

Although rhabdomyosarcoma is the most common soft tissue sarcoma in childhood, it is a very rare tumor in the neonatal period. It constitutes %5-8 of all malignant solid tumors in childhood. It is the third most common extracranial solid tumor of childhood and the most common soft tissue sarcoma after neuroblastoma and Wilms' tumor. Only %1-2 of all rhabdomyosarcomas occur in the neonatal period. It usually manifests as a growing mass anywhere on the body. The most common locations are the head-neck and genito-urinary system, close to the visceral organs such as the retroperitoneum, pelvis and abdomen, and the extremities. Here, we aimed to contribute to the literature by presenting a newborn born with a vaginal mass and diagnosed with botroid variant rhabdomyosarcoma.

Anahtar Kelimeler

Newborn, rhabdomyosarcoma, congenital mass

BİR YENİDOĞANDA RABDOMYOSARKOM: OLGU SUNUMU

Öz

Rabdomyosarkom çocukluk yaş grubunda en sık görülen yumuşak doku sarkomu olmakla birlikte, yenidoğan döneminde oldukça nadir rastlanan bir tümördür. Çocukluk çağındaki tüm malign solid tümörlerin %5-8'ini oluşturur. Nöroblastom ve Wilms tümöründen sonra çocukluk çağının üçüncü en yaygın ekstrakraniyal solid tümörü ve en yaygın yumuşak doku sarkomudur. Tüm rabdomyosarkomların ancak %1-2 kadarı yenidoğan döneminde görülür. Genellikle vücudun herhangi bir yerinde büyüyen bir kitle olarak bulgu verir. En sık yerleşim bölgeleri baş-boyun ve genito-üriner sistem olmak üzere retroperiton, pelvis ve batın gibi visseral organların komşuluğu ve ekstremitelerdir. Burada vajinal kitle ile doğan ve botroid varyant rabdomyosarkom tanısı alan bir yenidoğan sunularak literatüre katkıda bulunulmak istenmiştir.

Anahtar Kelimeler

Yenidoğan, rabdomyosarkom, konjenital kitle

Kaynakça

• 1. Dervişoğlu S, Çomunoğlu N, Kösemehmetoğlu K., Histopathology of soft tissue tumors and changes in classification, Turkish Journal of Oncology, 2015:30; 1-4.
• 2. Gong Y, Chao, J, Bauer B, Sun X, Chou PM. (2002), Primary cutaneous alveolar rhabdomyosarcoma of the perineum. Arch Pathol Labor Med 2015:126(8);982-984.
• 3. Pastore G, Peris-Bonet R, Carli M, Martínez-García C, de Toledo JS, Steliarova-Foucher E. (). Childhood soft tissue sarcomas incidence and survival in European children (1978–1997): report from the Automated Childhood Cancer Information System project. Eur J Cancer 2006:42(13);2136-2149.
• 4. Lanzkowsky P, Lipton JM, Fish JD, Lanzkowsky’s Manual of Pediatric Hematology and Oncology, Elsevier, 6th Edition, 2016; 308-309.
• 5. Mousavi A, Akhavan S. Sarcoma botryoides (embryonal rhabdomyosarcoma) of the uterine cervix in sisters. J Gynecol Oncol 2010:21(4);273-275.
• 6. Hilgers RD, Malkasian GD, Soule EH. Embryonal rhabdomyosarcoma (botryoid type) of the vagina: a clinicopathologic review. Am J Obstetr Gynecol 1970:107(3);484-502.
• 7. Weiss SW, Goldblum JR. Rhabdomyosarcoma. In: Weiss SW, Goldblum JR. eds. Enzinger and Weiss’s soft tissue tumors (4th edition). St Louis: CV Mosby, 2001:785-835.
• 8. Lobe TE, Wiener ES, Hays DM, et al. Neonatal rhabdomyosarcoma: The IRS experience. Journal of Pediatr Surgery, 1994;29:1167-70.
• 9. ALSaleh N, ALwadie H, Gari A. Rhabdomyosarcoma of the genital tract in an 18-month-old girl. Journal of Surgical Case Reports, 2017;2017(4):rjx080.
• 10. Van Sambeeck SJ, Mavinkurve-Groothuis AMC, Flucke U, Dors N. Sarcoma botryoides in an infant. BMJ Case Reports, 2014; doi:10.1136/bcr-2013-202080
• 11. Koukourakis GV, Kouloulias V, Zacharias G, Maravelis G, Papadimitriou C, Platoni K, Gouliamos A. Embryonal rhabdomyosarcoma of the uterine cervix. Clin Transl Oncol 2009:11(6);399-402.