High Eosinophilia Strongly Associated with Human Toxocariasis

Yıl 2019, Cilt: 4 Sayı: 3, 84 - 90, 30.09.2019

Ayşegül Aksoy Gökmen , Aylin Babaoğlu Bayram Pektaş Pektaş , Selçuk Kaya , Derya Dirim Erdoğan Metin Korkmaz

Öz

Backround: The aim of this study was to reveal the prevalence of toxocariasis in
patients with eosinophilia using Western blotting, and to show the importance
of eosinophilia for toxocariasis. Materials and
Methods: For this aim, 122 individuals, of whom 37 was without eosinophilia, were included to the study and in
their serum sample, presence of IgG against Toxocara
canis was investigated by Western
blotting. Patients with eosinophilia were divided into two groups. In the first group (n=52), eosinophilic cells constitute 3% to 10% of total
white cells (<10% ) whereas in the second group (n: 33) eosinophilic cells
constitute greater  than or equal to 10%
of total white cells (≥10%) . In addition, the cut-off value of the control group
(n=37) for eosinophilia was ≤3% of total white cells.

Results: According to the results that obtained
from the study, 62.3% (n=76/122) of all patients (including healthy people)
were found seropositive. Also, 97% of (n=32/33) patient serum samples with ≥10 eosinophilia
and 46.1% (n=24/52) of patient serum samples with <10% eosinophilia were found
to be positive when patients were categorized depending on eosinophilia levels.
Among control group serum samples with ≤3% eosinophilia (n=37), 54% of them
were detected to be positive.

Conclusion: Accordingly, the seropositivity
rate detected in patients with at least 10% eosinophilia was statistically
significant when compared with the other groups (P<0.05). Seropositivity values detected in patients with
eosinophilia are notable. Therefore, physicians should keep Toxocara spp. infection in mind in
patients with eosinophilia. 

Anahtar Kelimeler

Toxocara spp., human toxocariasis

Kaynakça

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