Synthesis of Linalool Imprinted Polymer

Yıl 2018, Cilt: 8 Sayı: 4, 205 - 212, 30.12.2018

Mert Soysal

https://doi.org/10.21597/jist.415454

Öz

Molecular imprinting has become a powerful tool for the preparation of three dimensional polymeric

materials with special recognition ability. The three dimensionally cross-linked polymeric materials are obtained by

polymerization of functional monomers in the presence of template molecule. Then, leaching of template molecules

by a leaching procedure generates the recognition cavities complementary to the shape, size and functional groups

of the template molecules. Thus, molecularly imprinted polymers are often used because of their stability, their

resistance to temperature and pressure, resistance to effects of the chemicals and their re-use, as well as their

selective properties against template molecule. Nowadays, molecular imprinting technique has been successfully

assembled with a several of analytical techniques in chromatography, sensor etc. Molecularly imprinted polymers

synthesized as a template molecule of linalool have been studied for the first time in the literature. In the synthesis

of molecularly imprinted polymers, methacrylic acid as a monomer and ethylene glycol dimethacrylate as crosslinker

were chosen. Imprinted polymers were synthesized by the suspension polymerization method. The carbon

paste was prepared by mixing the obtained imprinted polymers with graphite powder at appropriate ratios and

electrochemical measurements were made by filling this carbon paste into the hand-made electrodes.

Anahtar Kelimeler

Electrochemistry, linalool, molecular imprinted polymer

Linalool Baskılı Polimer Sentezi

Öz

Spesifik tanıma özelliği bakımından molekül baskılama tekniği, üç boyutlu polimerik malzemelerin

hazırlanmasında önemli bir araç haline gelmiştir. Üç boyutlu olarak çapraz bağlanmış polimerik malzemeler, kalıp

molekülünün bulunduğu ortamdaki fonksiyonel monomerlerin polimerizasyonu ile elde edilirler. Daha sonra,

uygun sökme prosedürüyle kalıp molekülünün şekil, boyut ve fonksiyonel gruplarına ait tamamlayıcı tanıma

bölgeleri oluşturulur. Böylelikle, molekül baskılı polimerler, kalıp moleküle karşı seçici özellik göstermesinin yanı

sıra kararlı bir yapıda bulunması, sıcaklığa ve basınca karşı dayanıklı, kimyasallara karşı dirençli olmaları ve tekrar

kullanılabilmeleri gibi özelliklerinden dolayı sıklıkla kullanılmaktadır. Günümüzde, moleküler baskılama tekniği,

kromatografi, sensör vb. gibi çeşitli analitik tekniklerle başarı bir şekilde birleştirilmiştir. Linalool maddesinin

kalıp molekül olarak sentezlenen molekül baskılı polimerler, literatürde ilk kez bu çalışma ile yapılmıştır. Molekül

baskılı polimerlerin sentezinde, monomer olarak metakrilik asit, çapraz bağlayıcı olarak da etilenglikol dimetakrilat

seçilmiştir. Baskılı polimerler süspansiyon polimerizasyonu yöntemiyle sentezlenmiştir. Elde edilen baskılı

polimerler ile grafit tozunun uygun oranlarında karıştırılmasıyla karbon pasta hazırlanmış ve elde imal edilmiş olan

elektrotların içerisine bu pasta doldurularak elektrokimyasal ölçümler yapılmıştır.

Anahtar Kelimeler

Elektrokimya, linalool, molekül baskılı polimer

Kaynakça

• Archer E, Castrignano E, Hordern B. K, Wolfaardt G. M, 2018. Wastewater-based epidemiology and enantiomeric profiling for drugs of abuse in South African wastewaters. Science of the Total Environment, 625: 192-800.
• Bayram E, Yılmaz E, Uzun L, Say R, Denizli A, 2017. Multiclonal plastic antibodies for selective aflatoxin extraction from food samples. Food Chemistry, 221: 829-837.
• Chellappandian M, Srinivasan P. V, Nathan S. S, Karthi S, Thanigaivel A, Ponsankar A, Kalaivani K, Hunter W. B, 2018. Botanical essential oils and uses as mosquitocides and repellents against dengue. Environment International, 113: 214-230.
• Demirkurt M, Olcer Y. A, Demir M. M, Eroğlu A.E, 2018. Electrospun polystyrene fibers knitted around imprinted acrylate microspheres as sorbent for paraben derivatives. Analytica Chimica Acta, 1014: 1-9.
• Elshafey R, Radi A. E, 2018. Electrochemical impedance sensor for herbicide alachlor based on imprinted polymer receptor. Journal of Electroanalytical Chemistry, 813: 171-177.
• Garcia R, Carreiro E. P, Ramalho, J. P. P, Mirao J, Burke A. J, Gomes da Silva M. D. R, Freitas A. M. C, Cabrita M. J, 2018. A magnetic controllable tool for the selective enrichment of dimethoate from olive oil samples: A responsive molecular imprinting-based approach. Food Chemistry, 254: 309-316.
• Li Y, Liu J, Zhang Y, Gu M, Wang D, Dang Y. Y, Ye B. C, Li Y, 2018. A robust electrochemical sensing platform using carbon paste electrode modified with molecularly imprinted microsphere and its application on methyl parathion detection. Biosensors and Bioelectronics, 106: 71-77.
• Mitrova K, Svoboda P, Milella L, Ovesna J, 2018. Alliinase and cycteine synthase transcription in developing garlic (Allium sativum L.) over time. Food Chemistry, 251: 103-109.
• Orozco J, Cortes A, Cheng G, Sattayasamitsathit S, Gao W, Feng X, Shen Y, Wang J, 2013. Molecularly imprinted polymer-based catalytic micromotors for selective protein transport. Journal of the American Chemistry Society, 135(14): 5336-5339.
• Ou S. H, Pan L. S, Jow J. J, Chen H. R, Ling T. R, 2018. Molecularly imprinted electrochemical sensor, formed on Ag screen-printed electrodes, for the enantioselective recognition of D and L phenylalanine. Biosensors and Bioelectronics, 105: 143-150.
• Roulette C. J, Njau E. F. A, Quinlan M. B, Quilan R. J, Call D. R, 2018. Medicinal foods and beverages among Maasai agro-pastoralists in northern Tanzania. Journal of Ethnopharmacology, 216: 191-202.
• Siciliano I, Ortega S. F, Gilardi G, Bosio P, Garibaldi A, Gullino M. L, 2018. Molecular phylogeny and characterization of secondary metabolite profile of plant pathogenic Alternaria species isolated from basil. Food Microbiology, 73: 264-274.
• Soysal M, Muti M, Esen C, Gençdağ K, Aslan A, Erdem A, Karagözler A. E, 2013. A novel and selective methylene blue imprinted polymer modified carbon paste electrode. Electroanalysis, 25(5): 1278-1285.
• Tang Z. G, Liu C. B, Wang J, Li H. M, Ji Y, Wang G. H, Lu C, 2016. Preparation and characterization of monodisperse molecularly imprinted polymers for the recognition and enrichment of oleanolic acid. Journal of Separation Science, 39: 1592-1602.
• Xu Y, Tang Y, Zhao Y, Gao R, Zhang J, Fu D, Li Z, Li H, Tang X, 2018. Bifunctional monomer magnetic imprinted nanomaterials for selective separation of tetracyclines directly from milk samples. Journal of Colloid and Interface Science, 515: 18-26.
• Yang S. K, Low L. Y, Yap P. S. X, Yusoff K, Mai C. W, Lai K. S, Lim S. H. E, 2018. Plant-derived antimicrobials: Insights into mitigation of antimicrobial resistance. Records of Natural Products, 12(4): 295-316.
• Zhang X, Yarman A, Erdossy J, Katz S, Zebger I, Jetzschmann K. J, Altıntaş Z, Wollenberger U, Gyurcsanyi R. E, Scheller F. W, 2018. Electrosynthesized MIPs for transferrin: Plastibodies or nao-filters?. Biosensors and Bioelectronics, 105: 29-35.