Nasal carriage frequency of Staphylococcus aureus according to education years of medical students

Yıl 2016, Cilt: 6 Sayı: 3, 103 - 106, 01.09.2016

Oguz Karabay

https://doi.org/10.5799/jmid.328963

Cited By: 1

Öz

Objective: Nasal carriage of Staphylococcus aureus (NCSa) is one of the most important risk factors for nosocomial
infection. Although there are numerous studies concerning NCSa frequency among medical staff, studies dealing specifically
with medical students are less common. We aimed to investigate NCSa frequency among medical students and
to compare the rates of clinical students (CS), comprising interns and stagers, with those of preclinical students (PS).
Materials and Methods: This study was performed at Sakarya University Medical School. All students were invited to
participate into the study. Nasal swab samples were taken anterior nares from 146 medical students (PS=82, CS=64).
The samples were inoculated into the Chapman agar medium, and incubated at 370
C for 48 hours. Antibiotic sensitivity
tests were performed on these colonies. The obtained data were analyzed statistically. Chi-square test was used for
qualitative variables and t test was used as quantitative data. P <0.05 was considered significant.
Results: A total of 146 students were agreed to participate in the study (53 subjects were male and 93 were female).
While NCSa frequency within the PS group was 2/82 (2.4%), that within the CS group was 7/64 (10.9%) (p=0.042). Methicillin
resistance was not detected in any subject.
Conclusion: As a result, the frequency of NCSa in the CS group (10.9%) was found to be about 4 times higher than that
in the PS group (2.4%). We recommend that clinical students should be expected to observe infection-control precautions.
J Microbiol Infect Dis 2016; 6(3): 103-106  

Anahtar Kelimeler

Nasal carriage, Staphylococcus aureus, medical student

Kaynakça

• 1. Ammerlaan HSM, Kluytmans JAJW, Wertheim HFL, Nouwen JL, Bonten MJM. Eradication of methicillin-resistant Staphylococcus aureus carriage: a systematic review. Clin Infect Dis 2009; 48: 922-30.
• 2. Kluytmans J, van Belkum A, Verbrugh H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev 1997; 10: 505-520.
• 3. Donker JMW, van der Laan L, Hendriks YJAM, Kluytmans JAJW. Evaluation of Staphylococcus aureus nasal carriage screening before vascular surgery. PLoS One 2012; 7: e38127.
• 4. Vanden Bergh MF, Yzerman EP, van Belkum A, Boelens HA, Sijmons M, Verbrugh HA. Follow-up of Staphylococcus aureus nasal carriage after 8 years: redefining the persistent carrier state. J Clin Microbiol 1999; 37: 3133-40.
• 5. El Helali N, Carbonne A, Naas T, et al. Nosocomial outbreak of staphylococcal scalded skin syndrome in neonates: epidemiological investigation and control. J Hosp Infect 2005; 61: 130-8.
• 6. Cirkovic I, Stepanovic S, Skov R, Trajkovic J, Grgurevic A, Larsen AR. Carriage and Genetic Diversity of Methicillin-Resistant Staphylococcus aureus among Patients and Healthcare Workers in a Serbian University Hospital. PLoS One 2015; 10: e0127347.
• 7. Karabay O, Otkun MT, Yavuz MT, Otkun M. Nasal carriage of methicillin-resistant and methicillin-susceptible Staphylococcus aureus in nursing home residents in Bolu, Turkey. West Indian Med J 2006; 55: 183-7.
• 8. Treesirichod A, Hantagool S, Prommalikit O. Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus among medical students at the HRH Princess Maha Chakri Sirindhorn Medical Center, Thailand: a follow-up study. J Infect Public Health; 7: 205-9.
• 9. Erdenizmenli M, Yapar N, Senger SS, Ozdemir S, Yuce A. Investigation of colonization with methicillin-resistant and methicillin-susceptible Staphylococcus aureus in an outpatient population in Turkey. Jpn J Infect Dis 2004; 57: 172-5.
• 10. Trépanier P, Tremblay C, Ruest A. Methicillin-resistant Staphylococcus aureus colonization among medical residents. Can J Infect Dis Med Microbiol 2013; 24: e39-41.