Isochamaejasmin and other flavonoids isolated from an endemic Algerian desert species

Year 2018, Volume: 5 Issue: 2, 347 - 354, 01.01.2018

Feyza Oke-altuntas , Labib Noman Amar Zellagui Ibrahim Demirtas , Rhouati Salah

https://doi.org/10.18596/jotcsa.351651

Abstract

Thymelaea
microphylla Coss. et Dur is an endemic desert species from Algeria belongs to Thymelaeaceae
family. The dichloromethane-methanolic extract from aerial parts of T.
microphylla was subjected to silica gel column. Three flavonoids were
isolated from the extract; isochamaejasmin (1), cis-tiliroside (2) and
trans-tiliroside (3). The structures of the compounds were determined on the
basis of the HPLC-TOF/MS, 1D and 2D NMR spectroscopic analysis. To the best of
our knowledge, compound (1) was isolated from T. microphylla for the
first time and there is no report in the literature. Moreover, in
this study, antioxidant activity of the compound (3) was also evaluated.

Keywords

Thymelaea microphylla, flavonoids, antioxidant

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