Determination of Antimicrobial, Antioxidant and Antidiabetic Effects of Viscum Album (Mistletoe) Extracts

Yıl 2020, , 380 - 394, 15.12.2020

Dorukhan Köse Filiz Gökçenaz Yiğit Gülüşan Tuncay Kadriye Özcan

https://doi.org/10.31466/kfbd.808898

Cited By: 1

Öz

Many plants in nature are rich in phenolic compounds and have natural antioxidant and antimicrobial properties. Therefore, plants have started to gain importance in the biotechnological field and are preferred as alternative sources for the treatment of chronic diseases. Today, it is thought that herbs with antidiabetic properties can be used in the treatment of diabetes, which is an important health problem. Because of this feature, plants have become the focus of researchers in recent years. It is thought that the mistletoe (Viscum album), which is one of these plants and used in the treatment of many diseases, can also be effective for the treatment of diabetes. For this reason, in this study, phenolic and flavonoid substance, antioxidant capacity, antimicrobial activity and enzyme inhibition activity of extracts prepared with three different solvents (chloroform, acetone, ethanol) of mistletoe grown on pear tree collected from Artvin Arhavi region were investigated. When the results obtained from the study are taken into consideration, it can be said that the mistletoe plant, which has a high biological activity today, has a potential of use in the pharmaceutical industry.

Anahtar Kelimeler

Viscum album, antimicrobial, antioxidant, enzyme inhibition, diabetes

Viscum Album (Ökse Otu) Ekstrelerinin Antimikrobiyal, Antioksidan ve Antidiyabetik Etkilerinin Belirlenmesi

Öz

Doğada bulunan birçok bitki, fenolik bileşik yönünden zengin olup doğal antioksidan ve antimikrobiyal özellikler taşımaktadır. Bu nedenle, bitkiler biyoteknolojik alanda önem kazanmaya ve kronik hastalıkların tedavisi için alternatif kaynak olarak tercih edilmeye başlanmıştır. Günümüzde önemli bir sağlık sorunu olan diyabet hastalığının tedavisinde anti-diyabetik özellik taşıyan bitkilerin kullanılabileceği düşünülmektedir. Bu özelliğinden dolayı bitkiler, son yıllarda araştırmacıların odak konusu haline gelmiştir. Bu bitkilerden birisi olan ve birçok hastalığın tedavisinde kullanılan ökse otunun (Viscum album), diyabet hastalığının tedavisi için de etkili olabileceği düşünülmüştür. Bu sebeple, bu çalışmada Artvin Arhavi bölgesinden toplanan armut ağacı üzerinde yetişen ökse otu bitkisinin üç farklı çözgen (kloroform, aseton, etanol) ile hazırlanmış ekstrelerinin fenolik ve flavonoid madde, antioksidan kapasite, antimikrobiyal aktivite ve enzim inhibisyon aktivite tayinleri yapılmıştır. Çalışmadan elde edilen sonuçlar göz önüne alındığında günümüzde yüksek bir biyolojik aktiviteye sahip olan ökse otu bitkisinin ilaç endüstrisinde kullanım potansiyelinin olduğu söylenebilir.

Anahtar Kelimeler

Viscum album, antimikrobiyal, antioksidan, enzim inhibisyon, diyabet

Kaynakça

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