Endometrial Örnekleme Yapılan Hastaların Sonografik Bulgularının ve Histopatolojik Sonuçlarının Değerlendirilmesi

Yıl 2018, Cilt: 10 Sayı: 1, 81 - 87, 28.03.2018

Sıtkı Özbilgeç Aşkı Ellibeş Kaya , Alper Başbuğ

https://doi.org/10.18521/ktd.338094

Cited By: 1

Öz

Amaç: Bu çalışmanın amacı, endometrial örnekleme yapılan olgularda histopatolojik sonuçlar
ve sonografik veriler arasındaki ilişkinin araştırılmasıdır.
Gereç ve Yöntem: Düzce Üniversitesi Tıp Fakültesi Hastanesi’nde Ocak 2015 - Ocak 2017
yılları arasında endometrial örnekleme yapılan hastaların sonuçları retrospektif olarak hastane
otomasyon sisteminden ve hasta dosyalarından incelenerek değerlendirildi. Hastalar
menopozal durumlarına göre premenopoz ve postmenopoz olarak sınıflandırılarak, hasta
gruplarındaki sonuçlar istatistiksel olarak karşılaştırıldı.
Bulgular: Hastaların 231’i premenopozal, 202’si postmenopozal dönemde idi. Premenopozal
hastaların ortalama endometrial kalınlıkları 10,42 ± 6,75 (mm, mean±SD) iken,
postmenopozal hastaların endometrial kalınlık ortalamaları 10,01 ± 7,26 (mm, mean±SD)
bulundu. Premalign lezyonların görülme oranı, her iki grupta benzer bulundu (p=0,87,
p=0,54). Postmenopozal 10 hastada malignite tanısı konuldu, bu hastaların tümünün ilk
başvuru şikayeti postmenopozal kanamaydı. Yapılan ROC analiz ile malignite için
endometrial kalınlık sınır değeri; 8,5 mm olarak bulundu. Premenopozal dönemde,
endometrial polip % 22,1 (n=51) oranında izlenirken, postmenopozal dönemde %16,3 (n=33)
oranında izlendi (p=0,014). Tamoksifen kullanan 8 hastanın patoloji sonucu %75 (n=6)
benign, %12,5 (n=1) premalign, %12,5 (n=1) malign olarak raporlandı.
Sonuç: Postmenopozal kanamalı hastalarda endometrial örnekleme malignite ekartasyonu
açısından hayatidir

Anahtar Kelimeler

Endometrial Kalınlık, Endometrium Kanseri, Endometrial Örnekleme, Postmenopoz

Evaluation of Sonographic Findings and Histopathologic Results of Endometrial Sampling Patients

Öz

Objective: The aim of this study was to investigate the relationship between histopathologic
results and sonographic data in cases of endometrial sampling.
Methods: The results of patients who underwent endometrial sampling between January 2015
and January 2017 at the Düzce University Medical Faculty Hospital were examined
retrospectively from the hospital computer system and patient files. Patients were classified as
premenopausal and postmenopausal groups according to the results of the patient groups were
compared statistically.
Results: Based on clasified, 231 of patients were premenopausal and 202 were
postmenopausal. The mean endometrial thickness of premenopausal patients was 10.42 ± 6.75
(mm, mean ± SD), whereas the mean endometrial thickness of postmenopausal patients was
10.01 ± 7.26 (mm, mean ± SD). Premalign lesions were observed in similar proportions in
both groups (p=0.87, p=0.54). Ten patients detected with malignancy, all of them were
postmenopause and had bledding. Endometrial thickness cut-off value for malignancy was
found 8.5 mm by ROC analysis. In premenopausal group, endometrial polyp was observed in
22.1% (n = 51) and 16.3% (n = 33) in postmenopausal period (p = 0.014). The histopathology
results of 8 patients using tamoxifen were 75% (n = 6) benign, 12.5% (n = 1) premalign and
12.5% (n = 1) malignant.
Conclusion: Endometrial sampling in postmenopausal symptomatic patients is crutial in
terms of malignancy exclusion

Anahtar Kelimeler

Endometrium Cancer, Endometrial Sampling, Endometrial Thickness, Postmenopause

Kaynakça

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