Fallopian tube metastasis in a patient with a history of breast cancer

Yıl 2017, , 54 - 57, 15.01.2017

Melek Karakurt Eryılmaz Fatma Yalçın Müsri Derya Kıvrak Salim Betül Ünal Gülgün Erdoğan Metin Kaba Hasan Şenol Coşkun

https://doi.org/10.5472/marumj.299425

Öz

Breast carcinoma metastasis to the fallopian tube is extremely

rare. Distinction between a primary fallopian tumor and metastasis

of breast cancer is crucial since treatment and prognosis are

different. However, it is difficult to confirm pathologically without

surgery. Herein, we report a 46-year-old woman with a history

of left modified radical mastectomy for breast cancer 13 years

ago, presenting with a left adnexial mass. She underwent total

abdominal hysterectomy with bilateral salpingo-oophorectomy.

Pathology findings revealed cytokeratin (CK) 7, ER, and PR

positive tumor cells. Mammoglobuline, P53, CK20, GCDFP-15

and, thrombomoduline were negative. HER2 was also 2+.

Fluorescence in situ hybridization (FISH) for HER2 was negative.

Based on the morphology and immunophenotype of the tumor,

we established the diagnosis as metastasis of breast cancer to the

fallopian tube.

Anahtar Kelimeler

Fallopian tube cancer, Breast cancer, Fallopian tube metastasis

Kaynakça

• Early Breast Cancer Trialists’ Collaborative Group
• (EBCTCG). Effects of chemotherapy and hormonal therapy
• for early breast cancer on recurrence and 15-year survival:
• an overview of the randomised trials. Lancet 2005;365:1687-
• 717. doi: 10.1016/S0140-6736(05)66544-0.