Nöroplastisite nedir? Neden Önemlidir?: Türleri ve temel mekanizmaları

Yıl 2021, Cilt: 5 Sayı: 1, 1 - 3, 23.04.2021

Burak Yuluğ , Ahmet Aslan

https://doi.org/10.30565/medalanya.908876

Öz

İnsan beyni, işlevsel beyin ağları oluşturmak için plastik bir şekilde birbirine bağlıdır. Bu dinamik ve esnek nöronal yeniden düzenleme süreci, özellikle hafıza, öğrenme ve travma sonrası durumlar söz konusu olduğunda, merkezi sinir sisteminde verimli bir yenilenme süreci için gereklidir. Bu yazıda, inme, Alzheimer Hastalığı ve travmatik beyin hasarı gibi nörodejeneratif hastalıklarda nörorehabilitasyon üzerine gelecekteki çalışmalar için önemli bir şablon görevi gören beyindeki nöroplastisite sürecinin altın-da yatan temel prensipleri ve mekanizmaları tanımlamaya çalıştık.

Anahtar Kelimeler

Aktiviteye bağlı plastisite;, Gelişimsel esneklik;, Lezyon sonrası plastisite;, uzun vadeli potansiyasyon;, Öğrenme;, Hafıza;

What is neuroplasticity? Why it is important?: Types and its basic mechanisms

Öz

The human brain is interconnected in a plastic manner to form functional brain net-works. This dynamic and flexible neuronal reorganization process is essential for an efficient regeneration process in the central nervous system, especially when it comes to memory, learning, and posttraumatic conditions. Here, we tried to define basic principles and the mechanisms underlying neuroplasticity process in the brain which serve as an important template for future studies on neurorehabilitation in neu-rodegenerative diseases, such as stroke, Alzheimer’s Disease and traumatic brain injury.

Anahtar Kelimeler

Activity-dependent plasticity,, Developmental plasticity,, Post-lesional plasticity,, Long-term potantiation,, Learning,, Memory,

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