Öz
Özet: Aldosteron fazlalığı sekonder ve endokrin hipertansiyon nedenlerinden birisidir. Mineralokortikoid fazlalığı aldosteron yüksekliği ve aldosteron-dışı nedenlerden oluşmaktadır. Radyolojik görüntülemeler ve testlerle sekonder hiperaldosteronizm tanısında artış olmaktadır. Laboratuvar testlerine yönelirken ilk basamak hiperaldosteronizmin varlığını göstermektir. Primer hiperaldosteronizm, yüksek plazma aldosteron konsantrasyonlarına eşlik eden düşük plazma renin aktivitesi, hipokalemi veya normokaleminin eşlik ettiği hipertansiyonla tanınır. Tanı ve ayırıcı tanısı ile cerrahi tedavi edilebilen hipertansiyon kliniği vardır.
Anahtar Kelimeler: hipertansiyon, hiperaldosteronizm
Abstract:
Excess of aldosterone is one of the causes of secondary and endocrine hypertension. Mineralocorticoid excess includes increase of aldosterone and reasons without aldosterone. Diagnosis of secondary hyperaldosteronism increases with using radiological images and blood tests. Showing the presence of hyperaldosteronism is the first step at the laboratory tests. Primary hyperaldosteronism is defined as elevated plasma aldosterone concentration accompanied with low plasma renin activity in patient who has hypertension with hypokalemia or normokalemia. Hypertension in primary hyperaldostenonism can be treated with surgery
therefore differential diagnosis is important .
Key Words: hypertension, hyperaldosteronism
Anahtar Kelimeler
Kaynakça
- Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M, Young WF Jr, Montori VM; Endocrine Society. Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2008;93(9):3266-81.
- Stowasser M, Taylor PJ, Pimenta E, Ahmed AH, Gordon RD. Laboratory investigation of primary aldosteronism. Clin Biochem Rev. 2010;31(2):39-56.
- Vaidya A, Halperin F, Alexander EK, Dluhy R. Hyperaldosteronism. In: De Groot LJ, Beck-Peccoz P, Chrousos G, Dungan K, Grossman A, Hershman JM, Koch C, McLachlan R, New M, Rebar R, Singer F, Vinik A, Weickert MO, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.2013 Aug 1.
- Torre JJ, Bloomgarden ZT, Dickey RA, Hogan MJ, Janick JJ, Jyothinagaram SG, Siragy HM; AACE Hypertension Task Force. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of hypertension. Endocr Pract. 2006;12(2):193-222. Erratum in: Endocr Pract. 2008;14(6):802-3.
- Özmen B, Özmen D. Primer Hiperaldosteronizmin Tanı ve Tedavisi. Turkiye Klinikleri J Med Sci 2007, 27:79-85
Öz
Kaynakça
- Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M, Young WF Jr, Montori VM; Endocrine Society. Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2008;93(9):3266-81.
- Stowasser M, Taylor PJ, Pimenta E, Ahmed AH, Gordon RD. Laboratory investigation of primary aldosteronism. Clin Biochem Rev. 2010;31(2):39-56.
- Vaidya A, Halperin F, Alexander EK, Dluhy R. Hyperaldosteronism. In: De Groot LJ, Beck-Peccoz P, Chrousos G, Dungan K, Grossman A, Hershman JM, Koch C, McLachlan R, New M, Rebar R, Singer F, Vinik A, Weickert MO, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.2013 Aug 1.
- Torre JJ, Bloomgarden ZT, Dickey RA, Hogan MJ, Janick JJ, Jyothinagaram SG, Siragy HM; AACE Hypertension Task Force. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of hypertension. Endocr Pract. 2006;12(2):193-222. Erratum in: Endocr Pract. 2008;14(6):802-3.
- Özmen B, Özmen D. Primer Hiperaldosteronizmin Tanı ve Tedavisi. Turkiye Klinikleri J Med Sci 2007, 27:79-85
Ayrıntılar
| Birincil Dil | TR, EN |
|---|---|
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 28 Kasım 2015 |
| Yayımlandığı Sayı | Yıl 2015 Cilt: 2 Sayı: 1 |