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A Rare Case of Acute Respiratory Distress Due to Hydrochloric Acid Inhalation

Yıl 2024, Cilt: 7 Sayı: 1, 58 - 62, 25.03.2024
https://doi.org/10.55517/mrr.1373202

Öz

Although lung injury due to inhalation of Hydrochloric acid (HCl) occurs frequently, imaging findings are not well known. In this case, we aimed to discuss the progression of the patient who developed ARDS (Acute Respiratory Distress Syndrome) after inhalation of hydrochloric acid and progressive during follow-up. A 37-year-old female patient who was followed for asthma was admitted to the outpatient clinic with complaints of sudden dyspnea and chest pain after cleaning with bleach at home. In both lungs, patchy glassy opacities and consolidations were observed, progressively progressing towards the periphery. The patient was clinically diagnosed as acute respiratory distress syndrome. Hydrochloric acid was detected as the etiological agent. Hydrochloric acid is a colorless, which is used as a powerful cleaning agent in everyday use. Radiologists should be aware of the radiographic findings of pulmonary intoxication. Some of these may be life-threatening and require urgent diagnosis. When the general condition of the patient is bad and the anamnesis cannot be obtained by clinicians, radiological findings can be recognized, and guidance tips can be given to the clinician. In this way, they should aim to reduce the mortality and morbidity by recognizing the fatal diseases such as ARDS which may develop in patients as a result of intoxication and with early treatment.

Kaynakça

  • Radermacher P, Maggiore SM, Mercat A. Fifty Years of Research in ARDS. Gas Exchange in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2017 Oct 15;196(8):964-984. doi: 10.1164/rccm.201610-2156SO.
  • Eijking EP, Gommers D, So KL, Vergeer M, Lachmann B. Surfactant treatment of respiratory failure induced by hydrochloric acid aspiration in rats. Anesthesiology. 1993 Jun;78(6):1145-51. doi: 10.1097/00000542-199306000-00019.
  • Screening information data sets (SIDS) in Organizing for Economic Co-operation Development (OECD) and World Health Organization (WHO). 2002. Available from: www.inchem.org ocuments/sids/sids/7647010.pdf.
  • Vural S. Transdermal Methanol Intoxication Via Folk Medicine. Journal of Emergency Medicine Case Reports. 2019 Apr; 10(2): 50-52. doi: 10.33706/jemcr.551137.
  • Rubin AE, Wang KP, Liu MC. Tracheobronchial stenosis from acid aspiration presenting as asthma. Chest. 2003 Feb;123(2):643-6. doi: 10.1378/chest.123.2.643.
  • Reiss LK, Uhlig U, Uhlig S. Models and mechanisms of acute lung injury caused by direct insults. Eur J Cell Biol. 2012 Jun-Jul;91(6-7):590-601. doi: 10.1016/j.ejcb.2011.11.004.
  • Stevens B, Koenig JQ, Rebolledo V, Hanley QS, Covert DS. Respiratory effects from the inhalation of hydrogen chloride in young adult asthmatics. J Occup Med. 1992 Sep;34(9):923-9.
  • Agency for toxic substances & disease registry (ATSDR). Medical Management Guidelines For Hydrogen Chloride. 2007. Available from: www.atsdr.cdc.gov/MHMI/mmg173.pdf.
  • Health Protection Agency (HPA). Hydrogen Chloride/ Hydrochloric Acid Toxicolological Overview. 2007. Available from: www.gov.uk/government/uploads/system/uploads/attachment_data/file /337689/hpa_hydrogen_chloride_toxicological _overview_v1.pdf.
  • 1Shim E, Choe Y, Kim JH, Kang E-Y, Oh YW, Chung YJ, at al. Computed tomographic and radiological analysis of HCl injury in human lungs. Mol Cell Toxicol. 2014 Jan; 10:433-442. doi: 10.1007/s13273-014-0048-1.

Hidroklorik Asit İnhalasyonuna Bağlı Nadir Bir Akut Solunum Sıkıntısı Vakası

Yıl 2024, Cilt: 7 Sayı: 1, 58 - 62, 25.03.2024
https://doi.org/10.55517/mrr.1373202

Öz

Hidroklorik asit inhalasyonuna bağlı akciğer hasarı sık görülmesine rağmen görüntüleme bulguları iyi bilinmemektedir. Bu vakada hidroklorik asit inhalasyonu sonrası ARDS (Akut Solunum Sıkıntısı Sendromu) gelişen ve kliniği kötüleşen hastanın durumunu tartışmayı amaçladık. Astım nedeniyle takip edilen 37 yaşında kadın hasta, evde çamaşır suyu ile temizlik yaptıktan sonra ani nefes darlığı ve göğüs ağrısı şikayeti ile polikliniğimize başvurdu. Her iki akciğerde çevreye doğru progresif olarak ilerleyen yamalı camsı opasiteler ve konsolidasyonlar gözlendi. Hastaya klinik olarak akut solunum sıkıntısı sendromu tanısı konuldu. Hidroklorik asit etiyolojik ajan olarak saptandı. Hidroklorik asit, günlük kullanımda güçlü bir temizlik maddesi olarak kullanılan renksiz bir maddedir. Radyologlar, pulmoner intoksikasyonların radyografik bulgularından haberdar olmalıdır. Bunlardan bazıları hayatı tehdit edici olabilir ve acil teşhis gerektirebilir. Hastanın genel durumu kötü olduğunda ve klinisyenler tarafından anamnez alınamadığında radyolojik bulgular tanınabilir ve klinisyene yol gösterici ipuçları verilebilir. Bu sayede hastalarda zehirlenme sonucu gelişebilecek ARDS gibi ölümcül hastalıkları erken tanıyarak ve erken tedavi ile mortalite ve morbiditeyi azaltmayı hedeflemelidirler.

Kaynakça

  • Radermacher P, Maggiore SM, Mercat A. Fifty Years of Research in ARDS. Gas Exchange in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2017 Oct 15;196(8):964-984. doi: 10.1164/rccm.201610-2156SO.
  • Eijking EP, Gommers D, So KL, Vergeer M, Lachmann B. Surfactant treatment of respiratory failure induced by hydrochloric acid aspiration in rats. Anesthesiology. 1993 Jun;78(6):1145-51. doi: 10.1097/00000542-199306000-00019.
  • Screening information data sets (SIDS) in Organizing for Economic Co-operation Development (OECD) and World Health Organization (WHO). 2002. Available from: www.inchem.org ocuments/sids/sids/7647010.pdf.
  • Vural S. Transdermal Methanol Intoxication Via Folk Medicine. Journal of Emergency Medicine Case Reports. 2019 Apr; 10(2): 50-52. doi: 10.33706/jemcr.551137.
  • Rubin AE, Wang KP, Liu MC. Tracheobronchial stenosis from acid aspiration presenting as asthma. Chest. 2003 Feb;123(2):643-6. doi: 10.1378/chest.123.2.643.
  • Reiss LK, Uhlig U, Uhlig S. Models and mechanisms of acute lung injury caused by direct insults. Eur J Cell Biol. 2012 Jun-Jul;91(6-7):590-601. doi: 10.1016/j.ejcb.2011.11.004.
  • Stevens B, Koenig JQ, Rebolledo V, Hanley QS, Covert DS. Respiratory effects from the inhalation of hydrogen chloride in young adult asthmatics. J Occup Med. 1992 Sep;34(9):923-9.
  • Agency for toxic substances & disease registry (ATSDR). Medical Management Guidelines For Hydrogen Chloride. 2007. Available from: www.atsdr.cdc.gov/MHMI/mmg173.pdf.
  • Health Protection Agency (HPA). Hydrogen Chloride/ Hydrochloric Acid Toxicolological Overview. 2007. Available from: www.gov.uk/government/uploads/system/uploads/attachment_data/file /337689/hpa_hydrogen_chloride_toxicological _overview_v1.pdf.
  • 1Shim E, Choe Y, Kim JH, Kang E-Y, Oh YW, Chung YJ, at al. Computed tomographic and radiological analysis of HCl injury in human lungs. Mol Cell Toxicol. 2014 Jan; 10:433-442. doi: 10.1007/s13273-014-0048-1.
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Acil Tıp, Göğüs Hastalıkları
Bölüm Olgu Sunumu
Yazarlar

Saim Türkoğlu 0000-0001-8247-2009

Nuruban Delal Baykal 0000-0002-5755-8625

Ali Mahir Gündüz 0000-0002-4471-4596

Cemil Goya 0000-0003-4792-8722

Esra Gürbüz 0000-0002-3123-0963

Yayımlanma Tarihi 25 Mart 2024
Gönderilme Tarihi 9 Ekim 2023
Yayımlandığı Sayı Yıl 2024 Cilt: 7 Sayı: 1

Kaynak Göster

Vancouver Türkoğlu S, Baykal ND, Gündüz AM, Goya C, Gürbüz E. A Rare Case of Acute Respiratory Distress Due to Hydrochloric Acid Inhalation. MRR. 2024;7(1):58-62.