Gut microbiata: underestimated or exaggerated?

Yıl 2018, Cilt: 1 Sayı: 2, 30 - 35, 31.10.2018

Tarkan Karakan

https://doi.org/10.33204/mucosa.476149

Öz

Human gastrointestinal
tract contains a large diversity of commensal microorganisms, which is many
times more than the human living cells. In the last decade, we had enormous
number of research on the association with diseases and gut microbiota
composition. There is a clear increase in the number of pathological conditions
associated with dysbiosis in time. Also, the range of diseases are increased
and distributed to many disciplines, non-gastrointestinal diseases are also
increasingly reported.  Gut microbiota
has multiple functions and new applications for diagnosis and therapeutics of
diseases. Probiotics are widely used in health and disease states. Probably
further high quality scientific research will determine the exact place of
microbiota and probiotics in human health in the future.

Anahtar Kelimeler

Gut microbiata, probiotics

Bağırsak mikrobiyotası: küçümsenmiş mi, abartılı mı?

Öz

İnsan gastrointestinal
sistemi, tüm insan hücrelerinee göre çok daha fazla sayıda ve büyük bir
çeşitlilikteki komensal mikroorganizmaları içerir. Son on yılda, bağırsak
mikrobiyotasının içeriği ve hastalıkların ilişkisi üzerine çok fazla sayıda araştırma
yaptık. Zaman içinde disbiyoz ile ilişkili patolojik durumların sayısında
belirgin bir artış olmuştur. Ayrıca, bu hastalıkların yelpazesi daha da
genişlemiş ve birçok disipline dağılmıştır. Gastrointestinal hastalıklar
dışındakiler giderek daha fazla rapor edilir olmuştur. Bağırsak mikrobiyatası
birçok fonksiyona sahip olmanın yanında hastalıkların tanı ve tedavisi için da
birçok yeni uygulamaya sahiptir. Probiyotikler, hastalık ve sağlıkta yaygın
olarak kullanılmaktadır. Yüksek kaliteli bilimsel araştırmalar, gelecekte,
mikrobiyota ve probiyotiklerin insan sağlığı üzerindeki gerçek yerini
belirleyecektir.

Anahtar Kelimeler

Bağırsak mikrobiyotası, probiyotikler

Kaynakça

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