Eosinophilic Pustular Dermatosis: After 50 Years

Yıl 2022, Cilt: 9 Sayı: 3, 309 - 311, 30.12.2022

Ceyda Tetik Aydoğdu , Suzan Demir Pektaş

https://doi.org/10.47572/muskutd.1122661

Öz

Eosinophilic pustular dermatosis (EPD) is a non-infectious dermatosis characterized by eosinophilic infiltration of hair follicles. It was first described by Ise and Ofuji in 1965 in a female case with pustules on the arms and face, and eosinophilic infiltration of the follicles and leukocytosis in the peripheral blood were detected in the histopathological examination, and this form is known as classical EPD. Over the years, apart from classical EPD, three forms of immunosuppression-related EPD (mostly HIV-related) and infantile EPD have been defined, and some researchers suggest that these three forms, which differ clinically from each other, should be considered as different diseases. We review this rare entity, more than fifty years after its description.

Anahtar Kelimeler

eosinophilic pustular dermatosis, eosinophilia, folliculitis

Eozinofilik Püstüler Dermatoz: 50 Yılın Ardından

Öz

Eozinofilik püstüler dermatoz (EPD), kıl folliküllerinin eozinofilik infiltrasyonu ile karakterize non-infeksiyöz bir dermatozdur. İlk kez 1965 yılında Ise ve Ofuji tarafından kollar ve yüzde püstüller izlenen kadın olguda histopatolojik incelemede foliküllerin eozinofilik infiltrasyonu ve periferik kanda lökositoz saptanması üzerine tanımlanmıştır ve bu form klasik EPD olarak bilinmektedir. Yıllar içinde klasik EPD dışında immünsupresyonla ilişkili EPD (çoğunlukla HIV ile ilişkili) ve infantil EPD olmak üzere üç formu tanımlanmıştır ve bazı araştırmacılar birbirinden klinik olarak büyük farklar gösteren bu üç formun farklı birer hastalık olarak ele alınmasını önermektedir. Tanımlanmasının üzerinden elli yıldan fazla süre geçen bu nadir antiteyi gözden geçirmekteyiz. 

Anahtar Kelimeler

eozinofilik püstüler dermatoz, follikülit, eozinofili

Kaynakça

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