Ülkemiz Kültür Bitkilerinden Persea americana Mill. (Avokado) ve Tıbbi Açıdan Değerlendirilmesi

Yıl 2020, Cilt: 10 Sayı: 1, 28 - 36, 31.01.2020

Ömerül Faruk Tavlı , Esra Eroğlu Özkan

https://doi.org/10.31020/mutftd.622300

Cited By: 4

Öz

Persea
americana meyveleri (avokado), 1500’lü yılların
başlarına kadar sadece Amerika yerlileri tarafından tüketilirken, Amerika
Kıtası’nın keşfiyle Avrupa tarafından tanınmış, sonrasında tüm dünyaya
yayılmıştır. Ülkemizde, meyvelerin besin olarak tüketiminin yaygınlaşması ve
ticari önem kazanması son yıllarda artış göstermiştir, ancak bitkinin kültüre
alınması 1980’li yıllara dayanmaktadır. Günümüzde, özellikle Antalya, Mersin ve
Hatay bölgelerinde P. americana
türünün birkaç varyetesi yetiştirilmektedir. İçerdiği mineraller (özellikle
potasyum), vitaminler (özellikle E ve C vitaminleri), protein, fitosteroller ve
yağ asitleriyle zengin bir kaynak olan avokado üzerinde yapılmış birçok çalışma
bulunmaktadır. Yapılan in vitro çalışmalar, yaprak ekstrelerinin anti-HIV, sitotoksik ve insektisidal  etkiye; çekirdek yağının gastroprotektif, antihelmintik
ve antioksidan etkiye; meyvenin ise antibakteriyel etkiye sahip olduğunu
göstermektedir. Bu çalışma ile P. americana
türünün kimyasal bileşimi, tıbbi etki ve kullanılışı üzerine yapılmış
araştırmaların derlenmesi, Türkiye’de yetişen  varyetelerin
öneminin vurgulanması ve tıbbi potansiyelinin değerlendirilmesi amaçlanmıştır.
Elde edilen bulgular Akdeniz bölgemizin toprak ve iklim koşullarının içerik
açısından zengin bitkiler yetişmesine uygun olduğunu, bu bitkinin tıbbi açıdan
değerlendirilmesi için ileri çalışmaların yapılması gerektiğini göstermektedir.

Anahtar Kelimeler

Persea americana, kimyasal içeriği, biyolojik aktiviteleri, tarihçesi, etnobotanik kullanılışı, avokado

Medical Evaluation of Persea americana Mill. (Avocado) Cultivated In Turkey

Öz

Persea americana (Avocado) fruits were consumed by only Native Americans until early
1500’s, while Europe was recognized by the discovery of the America Continent
and then spread all over the world. In Turkey, widespread consumption of the fruits
as nutrients and gaining commercial importance have increased in recent years,
but the cultivation of the plant dates back to the 1980s. Today, several
varieties of Persea americana species
are cultivated, especially in Antalya, Mersin, and Hatay. There are many
studies reveal that avocado is a rich source of minerals (especially
potassium), vitamins (especially vitamins E and C), protein, phytosterols, and
fatty acids. In vitro studies have
shown that the leaf extracts of P.
americana have anti-HIV, cytotoxic, and insecticidal effects; the seed oil has
gastroprotective, antihelminthic and, antioxidant effects; the fruit has antibacterial
effect. The study aims that to review the research studies on the chemical composition,
medicinal effect and usage of P. americana,
and also to determine and emphasize the medicinal potential of the cultivated
species in Turkey.The findings of this study indicate that the soil and climatic conditions
of the Mediterranean region are suitable for the growth of P. Americana with rich content, and further studies are
needed for the medical evaluation of this plant.

Anahtar Kelimeler

Persea americana, avocado, history, ethnobotanical uses, chemical composition, biological activities

Kaynakça

• 1. Adeboye JO, et al. A preliminary study on the hypotensive activity of Persea americana leaf extracts in anaesthetized normotensive rats. Fitoterapia. 1999;70(1):15-20.
• 2. Gutiérrez ML, Villanueva M. The avocado in the prehispanic time avocados in the prehispanic time. Proceedings of World Avocado Congress VI. 2007; Nov 12-16. Viña Del Mar, Chile.
• 3. Özdemir F, et al. Hasat zamanı ve hasat sonrası olgunluğa bağlı olarak bazı avokado (Persea americana mill) çeşitlerinin bileşimindeki değişimler. Gıda. 2004;29(2):177-183.
• 4. Adeyemi OO, Okpo SO, Ogunti OO. Analgesic and anti-inflammatory effects of the aqueous extract of leaves of Persea americana Mill (Lauraceae). Fitoterapia. 2002;73(5):375-380.
• 5. Hurtado-Fernández E, Fernández-Gutiérrez A, Carrasco-Pancorbo A. Avocado fruit-Persea americana. In: Rodrigues S, Silva E, Brito ESd, editors. Exotic Fruits Reference Guide. London: Academic Press;2018. pp:37-48.
• 6. Galindo-Tovar ME, Ogata-Aguilar N, Arzate-Fernández AM. Some aspects of avocado (Persea americana Mill.) diversity and domestication in Mesoamerica. Genet Resour Crop Evol. 2008;55(3):441-450.
• 7. Schaffer BA, Wolstenholme BN, Whiley AW. History, Distribution and Uses. In: Bruce S, Wolstenholme BN, Whiley AW, editors. The avocado: botany, production and uses. Wallingford: CABI;2013. pp:10-30.
• 8. Demirkol A. Avokado Islahı. Derim. 2001;18(2):56-71.
• 9. Galindo-Tovar ME, et al. The avocado (Persea americana, Lauraceae) crop in Mesoamerica: 10,000 years of history. Harv Pap Bot. 2007;12(2):325-335.
• 10. Popenoe W, Zentmyer GA. Early history of the avocado. California Avocado Society Yearbook. 1997;81(1):163-171.
• 11. Demirkol A. Avocado growing in Turkey. Proceedings of World Avocado Congress III. 1995; Oct 22-27; pp. 451 - 456. Tel Aviv, Israel.
• 12. Bayram S, Seyla T. Antalya koşullarında bazı avokado çeşitlerinin yetiştirilmesi üzerine düşük ve yüksek sıcaklıkların etkisi. Mediterr Agric Sci. 2008;21(1):97-104.
• 13. Dabas D, et al. Avocado (Persea americana) seed as a source of bioactive phytochemicals. Curr Pharm Des. 2013;19(34):6133- 6140.
• 14. Dreher ML, Davenport AJ. Hass avocado composition and potential health effects. Crit Rev Food Sci Nutr. 2013;53(7):738-50.
• 15. Ojewole JA, Amabeoku GJ. Anticonvulsant effect of Persea americana Mill (Lauraceae) (Avocado) leaf aqueous extract in mice. Phytother Res. 2006;20(8):696-700.
• 16. Hurtado-Fernández E, et al. Quantitative characterization of important metabolites of avocado fruit by gas chromatography coupled to different detectors (APCI-TOF MS and FID). Food Res Int. 2014;62(1):801-811.
• 17. Hurtado-Fernandez E, et al. Merging a sensitive capillary electrophoresis-ultraviolet detection method with chemometric exploratory data analysis for the determination of phenolic acids and subsequent characterization of avocado fruit. Food Chem. 2013;141(4):3492-503.
• 18. Wang W, Bostic TR, Gu L. Antioxidant capacities, procyanidins and pigments in avocados of different strains and cultivars. Food Chem. 2010;122(4):1193-1198.
• 19. Kosinska A, et al. Phenolic compound profiles and antioxidant capacity of Persea americana Mill. peels and seeds of two varieties. Journal of Agricultural Food Chemistry. 2012;60(18):4613-9.
• 20. Jiménez-Arellanes A, et al. Antiprotozoal and antimycobacterial activities of Persea americana seeds. BMC Complement Altern Med. 2013;13(1):109.
• 21. Athaydes BR, et al. Avocado seeds (Persea americana Mill.) prevents indomethacin-induced gastric ulcer in mice. Food Res Int. 2019;119(1):751-760.
• 22. Leite JJG, et al. Chemical composition, toxicity and larvicidal and antifungal activities of Persea americana (avocado) seed extracts. Rev Soc Bras Med Trop. 2009;42(2):110-113.
• 23. Alonso-Castro AJ, et al. Medicinal plants used in the Huasteca Potosina, Mexico. J Ethnopharmacol. 2012;143(1):292-298.
• 24. Abe R, Ohtani K. An ethnobotanical study of medicinal plants and traditional therapies on Batan Island, the Philippines. J Ethnopharmacol. 2013;145(2):554-565.
• 25. Jiofack T, et al. Ethnobotanical uses of medicinal plants of two ethnoecological regions of Cameroon. Int J Med Med Sci. 2010;2(3):60-79.
• 26. del Refugio Ramos M, et al. Two glucosylated abscisic acid derivates from avocado seeds (Persea americana Mill. Lauraceae cv. Hass). Phytochemistry. 2004;65(7):955-62.
• 27. Longuefosse JL, Nossin E. Medical ethnobotany survey in Martinique. J Ethnopharmacol. 1996;53(3):117-142.
• 28. Ososki AL, et al. Ethnobotanical literature survey of medicinal plants in the Dominican Republic used for women's health conditions. J Ethnopharmacol. 2002;79(3):285-298.
• 29. Gbolade A. Ethnobotanical study of plants used in treating hypertension in Edo State of Nigeria. J Ethnopharmacol. 2012;144(1):1-10.
• 30. Ajibesin KK, et al. Ethnobotanical survey of Akwa Ibom State of Nigeria. J Ethnopharmacol. 2008;115(3):387-408.
• 31. Tene V, et al. An ethnobotanical survey of medicinal plants used in Loja and Zamora-Chinchipe, Ecuador. J Ethnopharmacol. 2007;111(1):63-81.
• 32. Andrade-Cetto A. Ethnobotanical study of the medicinal plants from Tlanchinol, Hidalgo, Mexico. J Ethnopharmacol. 2009;122(1):163-71.
• 33. Magassouba FB, et al. Ethnobotanical survey and antibacterial activity of some plants used in Guinean traditional medicine. J Ethnopharmacol. 2007;114(1):44-53.
• 34. Nadembega P, et al. Medicinal plants in Baskoure, Kourittenga Province, Burkina Faso: an ethnobotanical study. J Ethnopharmacol. 2011;133(2):378-95.
• 35. Castro JA, et al. Ethnobotanical study of traditional uses of medicinal plants: The flora of caatinga in the community of Cravolndia-BA, Brazil. J Med Plants Res. 2011;5(10):1905-1917.
• 36. Wigg MD, et al. In-Vitro Virucidal and Virustatic anti HIV-1 Effects of Extracts from Persea Americana Mill,(Avocado) Leaves. Antiviral Chem Chemother. 1996;7(4):179-183.
• 37. Rosas-Pinon Y, et al. Ethnobotanical survey and antibacterial activity of plants used in the Altiplane region of Mexico for the treatment of oral cavity infections. J Ethnopharmacol. 2012;141(3):860-5.
• 38. Dike IP, Obembe OO, Adebiyi FE. Ethnobotanical survey for potential anti-malarial plants in south-western Nigeria. J Ethnopharmacol. 2012;144(3):618-26.
• 39. Novais MH, et al. Studies on pharmaceutical ethnobotany in Arrabida Natural Park (Portugal). J Ethnopharmacol. 2004;93(2- 3):183-95.
• 40. Pahua-Ramos ME, et al. Hypolipidemic effect of avocado (Persea americana Mill) seed in a hypercholesterolemic mouse model. Plant Foods Hum Nutr. 2012;67(1):10-6.
• 41. Asaolu MF, et al. Hypolipemic effects of methanolic extract of persea americana seeds in hypercholestrolemic rats. Journal of Medicine and Medical Sciences. 2010;1(4):126-128.
• 42. Anaka ON, Ozolua RI, Okpo SO. Effect of the aqueous seed extract of Persea americana mill (Lauraceae) on the blood pressure of sprague- dawley rats. Afr J Pharm Pharmacol. 2009;3(10):485-490.
• 43. Edem D, Ekanem I, Ebong P. Effect of aqueous extracts of alligator pear seed (Persea americana mill) on blood glucose and histopathology of pancreas in alloxan-induced diabetic rats. Pak J Pharm Sci. 2009;22(3):272-6.
• 44. Engel N, et al. Proliferative effects of five traditional Nigerian medicinal plant extracts on human breast and bone cancer cell lines. J Ethnopharmacol. 2011;137(2):1003-10.
• 45. Oberlies NH, et al. Cytotoxic and insecticidal constituents of the unripe fruit of Persea americana. J Nat Prod. 1998;61(6):781- 785.
• 46. Nayak BS, Raju SS, Chalapathi Rao AV. Wound healing activity of Persea americana (avocado) fruit: a preclinical study on rats. J Wound Care. 2008;17(3):123-125.
• 47. Brai BI, Odetola AA, Agomo PU. Hypoglycemic and hypocholesterolemic potential of Persea americana leaf extracts. J Med Food. 2007;10(2):356-60.
• 48. Miranda MMFS, et al. In vitro activity of extracts of Persea americana leaves on acyclovir-resistant and phosphonoacetic resistant Herpes simplex virus. Phytomedicine. 1997;4(4):347-352.
• 49. Owolabi MA, Jaja SI, Coker HA. Vasorelaxant action of aqueous extract of the leaves of Persea americana on isolated thoracic rat aorta. Fitoterapia. 2005;76(6):567-73.
• 50. Lima CR, et al. Anti-diabetic activity of extract from Persea americana Mill. leaf via the activation of protein kinase B (PKB/Akt) in streptozotocin-induced diabetic rats. J Ethnopharmacol. 2012;141(1):517-25.
• 51. Gomez-Flores R, et al. Antimicrobial activity of Persea americana mill (Lauraceae) (Avocado) and gymnosperma glutinosum (Spreng.) less (Asteraceae) leaf extracts and active fractions against Mycobacterium tuberculosis. AEJSR. 2008;3(2):188-194.