HEPATİT B NEDENİYLE KARACİĞER NAKLİ YAPILAN HASTALARDA NÜKSÜ ETKİLEYEN FAKTÖRLER

Yıl 2019, Cilt: 14 Sayı: 2, 117 - 121, 16.04.2019

Gökhan Ertuğrul

Öz

Bu çalışmada, kliniğimizde Hepatit B Virus (HBV)
nedeniyle karaciğer nakli yapılan hastalarda nükse etki edebilecek faktörler
retrospektif olarak değerlendirildi. Çalışmada HBV nedeniyle karaciğer nakli
yapılan hastalar nakil sonrası nüks açısından iki gruba ayrıldı. Bu iki grup
arasında nükse etki edebilecek faktörler istatistiksel olarak değerlendirildi. Nisan
2014 ile Nisan 2018 tarihleri arasında merkezimizde 42(24.7) hastaya HBV
nedeniyle karaciğer nakli yapıldı. Bu hastaların 5(%11.9)’inde nüks görüldü.
Nüks gelişen hastalarda nakil öncesi HBV DNA kopya sayısının istatistiksel
olarak anlamlı bir şekilde daha yüksek olduğu saptandı.

Anahtar Kelimeler

Hepatit B Virus, Karaciğer Nakli, Nüks, Takrolimus, Siklosporin

Kaynakça

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