A retrospective evaluation of the prevalence of anti-Echinococcusgranulosus in patients with suspected cystic echinococcosis at İnönü University Faculty of Medicine TurgutÖzal Medical Center between 2018 and 2022

Yıl 2022, Cilt: 9 Sayı: 3, 94 - 103, 31.12.2022

Türkan Mutlu Yar , Tülay Aksoy İpek Balıkçı Çiçek , Metin Atambay

Öz

Objective: Cystic echinococcosis (CE) is a common zoonotic disease in the world, caused by the larval form of Echinococcus granulosus got lodged in various organs in both animals and humans. This study aimed to retrospectively examine ELISA test results in patients who applied to Inonu University Faculty of Medicine Parasitology Department with the suspicion of cystic echinococcosis.
Methods: The study was performed via ELISA to detect the presence of anti - E. granulosus immunoglobulin G (IgG) antibodies in the patients who came to the Parasitology Department with the suspicion of CE between January 2018 and June 2022.
Results: It was observed that E. granulosus antibody was detected as positive in 1353 (63.7%) and negative in 772 (36.3%) of the serum samples of 2128 patients admitted with the suspicion of hydatid cyst. Of 1353 cases with positive anti-E. granulosus IgG antibodies, 700 (51.74%) were females and 653 (48.26%) were males.
Conclusion: The retrospective study presented is intended to raise awareness of public health. As in Turkey, it is necessary to inform the public about CE in Malatya region, to draw the attention of the authorities to this issue, and to establish protection and control programs quickly. And it is recommended that these retrospective studies should be repeated to determine the importance of prevalence from time to time.

Anahtar Kelimeler

Cystic Echinococcosis, Echinococcusgranulosus, ELISA, Malatya

Kaynakça

• 1. Arslan ÖM, Mor N, Bedir H. Seropozitifity of anti- Echinococcus granulosus in patients with of clinical prediagnosis cystic Echinococcosis at Kafkas University health research and application hospital. T.Parazitol. Derg. 2022; 46(2):129-32.
• 2. Alver O, Payaslıoğlu MA, Özakın C, Esen S. Laboratory results of cystic Echinococcosis in 2017-2018. T.Parazitol. Derg. 2021; 45(3): 207-210.
• 3. Aktar SG, Ayaydın Z and et al. Retrospective evaluation of cases with the pre-diagnosis of cystic echinococcosis admitted to the microbiology laboratory of Diyarbakır health sciences Gazi Yaşargil training and research hospital between 2014 and 2017. T.Parazitol. Derg. 2020; 44(4): 207-10.
• 4. Altintas N. Pasttopresent: echinococcosis in Turkey. Acta Trop.2003; 85: 105-12.
• 5. Amman R, Eckert J. Cestodes: Echinococcus. Gastroenterology clinics of North american 1996; 25: 655-89.
• 6. Çelik T, Alev C, Akgün S, Güldoğan E, Şahin F. A retrospective evaluation of serobgical results of cystic echinoccosis suspected cases admitted to Adıyaman training and research hospital between 2013-2020. T.Parazitol. Derg. 2022; 46(2): 140-4.
• 7. Yürük M, Yaman O, Sivcan E, Erdoğan E. Retrospective deterrmination of the prevelense of anti- Echinococcus granulosus antibodies in cystic Echinococcosis Pre- diagnosed patients at Erciyes University Faculty of Medicine. T.Parazitol. derg 2022;46/2: 133-9.
• 8. Beyhan YE, Babür C, Mungan M, Özkan Taylan A, Evaluation of cystic echinococcosis suspected patients applied to national parasitology reference laboratory of public health Institution of Turkey between 2009-2013. Turkey Parazitol Derg2015;39:17-21.
• 9. Altıntaş N, Yazar S, Yolasığmaz A, Akısü Ç, Şakru N, Karacasu F, et al. A serum epidemiological study of cystic echinococcosis in İzmir and its surrounding area.Turkey helminthologia 1999; 36: 19-23.
• 10. Çetinkaya Z, Çiftçi IH, Demirel R, Altındiş M, Ayaz E. A sero- epidemiological study on cysticechinococcosis in Mid western region of Turkey. Saudi Med J 2005;26: 350-1.
• 11. Kilimcioğlu AA, Özkol M, Bayındır P, Girginkardeşler N, Ostan I, ok uz. The value of ultrasonography alone in screening surveys of cystic echinococcosis in children in Turkey. Parasitol Int 2006; 55: 273-5.
• 12. Eşgin M, Aktaş M, Coşkun Ş, The investigation of antibody presence in the sera of patientswith a suspicion of cystic echinococcosiz by using in direct hemaglutination test(IHA) Turkey Parasitol Derg 2007;31: 283-7.
• 13. Yazar S, Taylan Özkan A, Hökelek M, Polat E, Yılmaz, Özbilge H, et al. Cysticechinococcosis in Turkeyfrom 2001-2005. Turkey Parasitol Derg 2008; 32: 208-20.
• 14. Güreser AS, Özcan O, Özürel L, Boyacıoğlu Zİ, Taylan Özkan HA. Evaluation of Radiological, Biochemical and serological parameters of patients prediagnosed as cystic Echinococcosis in Çorum, Turkey Mikrobiyol Bul 2015; 49: 231-49.
• 15. Taş Cengiz Z, Yılmaz H, Beyhan YE, Kotan MC, Çobanoğlu V, Ekici A, et al. Cystic Echinococcosis seropositivity in the blood samples sent toparasitology laboratory of in the blood samples sent to parasitology laboratory of Yüzüncü Yıl University Medical Faculty between 2005-2013. Retrospective Assessment Turkey Parazitol. Derg 2015; 39:209-11.
• 16. Yazar S, CysticEchinococcosis in Kayseri during the last six years. Turkey Parazitol derg 2005;29:241-3.
• 17. Karaman Ü, Daldal N, Atambay M, Aycan MÖ. Serological results of cases with a presumptive diagnosis of hydatid cyst during 1999-2002 in the Inönü University Medical Faculty, Malatya. İnönü Univ. Tıp Fak Derg 2002; 9: 233-5.
• 18. Karaman Ü, Miman Ö, Kara M, Gıcık Y, Aycan ÖM, Atambay M. Hydatidcyst prevalence in the region of Kars. Turkey Parazitol Derg 2005;29: 238-40.
• 19. Çetinkaya Ü, Hamamcı B, Kaya M, Gücüyetmez S, Kuk S, Yazar S, et al. Investigation of Anti- Echinococcus granulosus antibodies in patients with suspected cystic Echinococcosis Turkey Parazitol, Derg 2012; 36: 57-60.
• 20. Ertabaklar H, Yıldız İ, Malatyalı E, Tileklioğlu E, Çalışkan SÖ, Ertuğ S. Retrospective Analysis of cystic echinococcosis results in Aydın Adnan Menderes University training and research hospital parasitology Laboratory between 2005 and 2017. TurkeyParazitolDerg 2019;43: 118-22.