Evaluation of the Differences Between Office and Ambulatory Blood Pressure Values in Children with Structurel Renal Anomaly.

Yıl 2019, Cilt: 41 Sayı: 2, 123 - 131, 01.04.2019

Nuran Çetin , Aslı Kavaz Tufan

https://doi.org/10.20515/otd.470998

Öz

Structural renal abnormalities
are one of the most common causes of hypertension in children. In this study,
it was aimed to compare office blood pressure (OBP) and ambulatory blood
pressure monitoring  (ABPM) values in
children with structural renal abnormalities. The data from patients with
structural renal abnormalities who performed ABPM were evaluated in this study.
It was investigated whether there were significant differences between OBP and
ABPM values. The paired t-test was used to determine the significance of the
differences between OBP and ABPM values. The factors affecting the differences
between office and ambulatory blood pressure values were investigated using
linear regression analysis. The OBP values were significantly higher than
nighttime systolic blood pressure (SBP) and diastolic blood pressure (DBP)
(p<0.01). The OBP values were positively correlated with all differences
(p<0.05). Age and body mass index were positively associated with
OBP–nighttime SBP difference (p = 0.001, p = 0.015, respectively). Serum blood
urea nitrogen level was positively associated with OBP–nighttime DBP and
OBP–24h DBP differences (β = 0.220,  p =
0.033, β = 0.205,  p =  0.045, respectively). There was a negative
correlation between glomerul filtration rate and OBP–nighttime SBP difference
(β = -0.05,  p = 0.01). The performing of
ABPM and the evaluation of the differences between office and ambulatory blood
pressure is very important in the early recognition of the hypertension in
children with structural renal anomaly.

Anahtar Kelimeler

Office blood pressure, ambulatory blood pressure, structural renal abnormalities

Yapısal Böbrek Anomalisi olan Çocuklarda Ofis ve Ambulatuvar Kan Basıncı Arasındaki Farklılıkların Değerlendirilmesi

Öz

Yapısal böbrek anomalileri
çocukluk döneminde görülen hipertansiyonun en sık nedenlerinden biridir. Bu
çalışmada yapısal böbrek anomalisi olan çocuklarda ofis kan basıncı (OKB) ile
ambulatuar kan basıncı izlemi (AKBİ) sonuçlarının karşılaştırılması
amaçlanmıştır. Bu çalışmada AKBİ yapılan yapısal böbrek anomalili hastaların
sonuçları değerlendirildi. Hastaların OKB ile AKBİ değerleri arasında anlamlı
farklılık olup olmadığı araştırıldı. OKB ve AKBİ sonuçları arasındaki
farklılıkların anlamlılığını belirlemek için t-testi (paired samples t-test)
kullanıldı. Farklılıkları etkileyen faktörler lineer regresyon analizi ile
araştırıldı.OKB değerleri gece sistolik kan basıncı (SKB) ve diastolik kan
basıncı (DKB) değerlerinden anlamlı olarak daha yüksekti (p<0.01). OKB
değerleri farklılıkların hepsi ile pozitif korele bulundu (p<0.05). Gece SKB
ile OKB arasındaki farklılıklar yaş ve vücut kitle indeksi ile pozitif yönde
koreleydi (sırası ile p = 0.001, p = 0.015). Kan üre azotu ile OKB - gece DKB
ve OKB - 24 saat DKB farklılıkları arasında anlamlı ilişki olduğu belirlendi
(sırası ile β = 0.220,  p = 0.033, β =
0.205,  p =  0.045). Glomerul filtrasyon hızı ve OKB-gece
SKB farklılığı arasında anlamlı negatif ilişki olduğu saptandı (β = -0.05,  p = 0.01). 
Yapısal böbrek anomalisi olan çocukların izlemi sırasında AKBİ yapılması
ve ofis ile ambulatuvar kan basınçları arasındaki farklılıkların
değerlendirilmesi hipertansiyonun erken dönemde tanınmasında oldukça önemlidir. 

Anahtar Kelimeler

Office blood pressure, ambulatory blood pressure, structural renal abnormalities

Kaynakça

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