Clinical, Dermoscopic and Histopathologic Correlation in Melanocytic Nevi

Yıl 2019, Cilt: 41 Sayı: 3, 262 - 270, 01.07.2019

Asude Kara Polat , İlham Sabuncu Evrim Yılmaz Zeynep Nurhan Saraçoğlu , Ayşe Esra Koku Aksu , Muzaffer Bilgin

https://doi.org/10.20515/otd.457625

Öz

Dermoscopy
is a noninvasive technique that facilitates the diagnosis of melanocytic nevus
(MN). Different algorithms are used in the differential diagnosis of
melanocytic lesions. In this study, we aimed to correlate the sensitivity and
specificity of the ABCD rule, 7 point control list and pattern analysis in MN. A
total of 60 MNs of 38 patients who applied to dermatology outpatient clinic
have been evaluated. Hand dermatoscopy (Dermatoscope Delta 10) and digital
dermatoscope (MoleMax II) were used for dermoscopic examination, and  each of the dermoscopic images were assessed
with the pattern analysis, the 7 point checklist and the ABCD rule. After
dermoscopic examination, lesions were examined histopathologically following
excisional or punch biopsy. The concordance between dermoscopic and
histopathologic diagnosis were evaluated. In
our study, the sensitivities of ABCD rule, 7 point control list and pattern
analysis were 94.6%, 92.9% and 97.5% respectively. The specificities were 78.3%,
 85% and 95% respectively. According to
our study, pattern analysis method had
the highest specificity and sensitivity.  

Melanositik Nevuslarda Klinik, Dermoskopik ve Histopatolojik Korelasyon

Öz

Dermoskopi,
melanositik nevuslara (MN) tanı konmasını kolaylaştıran noninvazif bir
tekniktir. Melanositik lezyonların ayırıcı tanısında farklı algoritmalar
kullanılmaktadır. Bu çalışmada MN’larda ABCD kuralı, 7 nokta kontrol listesi ve
patern analizinin duyarlılık, özgüllük ve tanısal doğruluklarının korelasyonu
amaçlanmıştır. Çalışmamızda dermatoloji polikliniğine başvuran 38 hastaya ait
toplam 60  MN klinik, dermoskopik ve
histopatolojik olarak değerlendirilmiştir. Dermoskopik muayenede el dermoskopu
(Dermatoskop Delta 10) ve digital dermoskop (MoleMax II) kullanılmış; her bir
lezyon ABCD kuralı, 7 nokta kontrol listesi ve patern
analizine göre skorlanmıştır. Dermoskopik muayene sonrası lezyonlar eksizyon
veya punch biyopsi ile alınarak histopatolojik olarak incelenmiş; dermoskopik
ve histopatolojik tanıların uyumluluğu değerlendirilmiştir. Çalışmamızda ABCD
kuralının, 7 nokta kontrol listesinin ve patern analizinin duyarlılıkları  sırasıyla %94.6, %92.9 ve %97.5 olarak
saptanırken;  özgüllükleri ise sırasıyla
%78.3,  %85  %95 olarak bulunmuştur. Çalışmamıza göre
melanositik lezyonların patern analizi yöntemi en yüksek özgüllük ve
duyarlılılığa sahiptir. 

Anahtar Kelimeler

Dermoskopi, ABCD kuralı, 7 nokta kontrol listesi, patern analizi, Histopatoloji

Kaynakça

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