Effect of the Neutrophil-Lymphocyte Ratio and Red Blood Cell Distribution Width On Postoperative Prognosis

Yıl 2024, Cilt: 46 Sayı: 6, 900 - 905, 07.11.2024

Resul Ekici , Dilek Çetinkaya , Ferda Yaman , Sadettin Dernek

https://doi.org/10.20515/otd.1518924

Öz

It has been stated that red blood cell distribution width (RDW) and neutrophil-lymphocyte ratio (NLR) have prognostic value in cardiovascular surgery, as well as various clinical conditions. This study aimed to determine whether preoperative NLR and RDW values had an effect on postoperative mortality and morbidity in patients undergoing isolated heart valve surgery.
Methods: This study was retrospectively conducted by examining the medical records of patients who underwent isolated heart valve replacement surgery between 2016 and 2020. Preoperative RDW and NLR values, postoperative extubation, mechanical ventilation, intensive care unit stay, and hospital stay, presence of postoperative cerebrovascular disease (CVD) and new-onset atrial fibrillation (AF), and dialysis requirement were recorded. The data of 68 patients were evaluated. In all the patients, the mean preoperative NLR value was 4.67±3.67, and the mean preoperative RDW value was 15.06±2.19. The NLR and RDW values were determined as 4.91(p=0.756) and 15.48 (p=0.032); respectively in the patients that developed postoperative AF, 3.34 and 17.56, respectively in those that developed postoperative CVD, and 9.26 and 14.93, respectively in those that required dialysis. Although preoperative the NLR and RDW values were high among the patients undergoing heart valve replacement surgery, it is not possible to state that these two markers have prognostic value for postoperative adverse events in this patient population.

Anahtar Kelimeler

Heart Valve Surgery, Neutrophil-Lymphocyte Ratio, Red Blood Cell Distribution Width

Preoperatif Nötrofil-Lenfosit Oranının ve Eritrosit Dağılım Genişliğinin İzole Kalp Kapak Ameliyatlarında Postoperatif Prognoza Etkisi

Öz

Kırmızı kan hücresi dağılım genişliği (RDW) ve nötrofil-lenfosit oranının (NLR), çeşitli klinik durumlar yanında kardiyovasküler cerrahide prognostik değere sahip olduğu belirtilmektedir. Bu çalışmada, izole kalp kapak ameliyatı geçiren hastalarda preoperatif NLR ve RDW değerinin postoperatif mortalite ve morbiditede etkisi olup olmadığını gözlemlemeyi amaçladık. Bu çalışma 2016-2020 tarihleri arasında izole kalp kapak replasman cerrahisi uygulanan hastaların tıbbi kayıtlarının geriye dönük incelenmesi ile oluşturulmuştur. Ameliyat öncesi RDW ve NLR değerleri, ameliyat sonrası ekstübasyon, mekanik ventilasyon, yoğun bakım kalış ve hastanede kalış süreleri, ameliyat sonrası serebrovasküler hastalık (SVH) ve yeni başlayan atriyal fibrilasyon (AF) varlığı ve diyaliz gereksinimi kaydedildi. Toplam 68 hastanın verileri değerlendirildi. Tüm hastaların ameliyat öncesi ortalama NLR değeri 4,67±3,67, ameliyat öncesi ortalama RDW değeri ise 15,06±2,19 idi. NLR ve RDW değerleri postoperatif AF gelişen hastalarda sırasıyla 4,91(p=0.756) ve 15,48 (p=0.032); postoperatif SVH gelişen hastalarda sırasıyla 3,34 ve 17,56; diyaliz gerektiren hastalarda sırasıyla 9,26 ve 14,93 olarak belirlendi. Kalp kapak replasman ameliyatı geçiren hastalarda ameliyat öncesi NLO ve RDW değerleri yüksek olmasına rağmen bu iki belirtecin bu hasta popülasyonunda ameliyat sonrası istenmeyen olaylar açısından prognostik değere sahip olduğunu söylemek mümkün değildir.

Anahtar Kelimeler

Kalp Kapak Ameliyatı, Nötrofil-Lenfosit Oranı, Kırmızı Kan Hücresi Dağılım Genişliği

Kaynakça

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