Beyin Natriüretik Peptid ve Pediatride Kullanım Alanları

Yıl 2010, Cilt: 8 Sayı: 3, 67 - 71, 01.12.2010

A. Barış Akcan , Nihal Oygür

Öz

Natriüretik peptid ailesi NP , sekiz ve daha fazla birbiriyle ilişkili peptidi içermektedir.Bunlar, 126 aminoasitten oluşan atrial natriüretik peptid ANP prohormonu, 108aminoasitten oluşan brain natriüretik peptid BNP prohormonu, ve 126 aminoasittenoluşan C tipi natriüretik peptid CNP prohormonudur. Natriüretik peptidler sonzamanlarda tanımlanmış olmalarına karşın potansiyel klinik öneme sahiptirler.Natriüretik peptidler, kardiyovasküler hastalıkların tanısı, tedaviye yanıtın ve prognozun değerlendirilmesinde yeni aday markerlardır

Anahtar Kelimeler

BNP, kardiyak fonksiyon, natriüretik peptidler

Brain Natriuretic Peptide and Applications in Pediatrics

Öz

Family of natriuretic peptides NP , consists of eight or more peptides associatedwith each other. These are, atrial natriuretic peptide ANP prohormone consisting of126 amino acids; brain natriuretic peptide BNP prohormone consisting of 108amino acids; C-type natriuretic peptide CNP prohormone consisting of 126 aminoacids. Although recently identified, natriuretic peptides have potential clinical significance. Natriüretic peptide family seems to be a “novel candidate marker”for the assessment of diagnosis, therapeutic response and prognosis in cardiovascular disease

Anahtar Kelimeler

BNP, cardiac function, natriuretic peptides

Kaynakça

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