Role of Intestinal Microbiota in Patients with Anorexia Nervosa

Yıl 2022, Cilt: 14 Sayı: 1, 65 - 73, 31.03.2022

Negin Almasi , Arzu Kabasakal Çetin , Zeynep Göktaş

https://doi.org/10.18863/pgy.944592

Öz

Anorexia nervosa is a psychiatric disorder characterized by severe low body weight, impaired self-body image, and intense fear of gaining weight, however its etiopathogenesis is not fully known. Some studies show that nutritional rehabilitation and corresponding weight restoration are not effective enough in the management of intestinal dysbiosis in patients with anorexia nervosa, but results are inconclusive. This work aims to review the existing studies to provide information about the possible role of intestinal microbiota in the pathophysiology of anorexia nervosa, characteristics of intestinal dysbiosis in patients with anorexia nervosa, and possible treatment approaches in the management of intestinal microbiota.

Anahtar Kelimeler

Anorexia nervosa, microbiota, dysbiosis

Anoreksiya Nervosalı Hastalarda İntestinal Mikrobiyotanın Rolü

Öz

Özet
Düşük vücut ağırlığı, bozulmuş beden algısı ve kilo alma korkusu ile karakterize psikiyatrik bir bozukluk olan anoreksiya nervozanın etiyopatogenezi tam olarak bilinmemektedir. Literatürde yer alan çalışmalar anoreksiya nervosalı hastalarda beslenme rehabilitasyonunun ve yeniden ağırlık kazanımının intestinal disbiyoz yönetiminde yeterince etkin olmadığını göstermektedir, ancak çalışmaların sonuçları karmaşıktır. Bu derlemede intestinal mikrobiyotanın anoreksiya nervosa patofizyolojisindeki olası rolü, anoreksiya nervosalı hastalarda intestinal disbiyoza ilişkin özellikler ve intestinal mikrobiyota yönetiminde olası tedavi yaklaşımları hakkında bilgi verilmesi amaçlanmıştır.

Anahtar Kelimeler

Anoreksiya nervoza, mikrobiyota, disbiyoz

Kaynakça

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