Obez adolesanlarda ventrikül geometrisi ve kardiyak fonksiyonların ekokardiyografi ile değerlendirilmesi

Year 2025, Volume: 13 Issue: 1, 7 - 13, 28.03.2025

Büşra Türk , Hakan Altın , Murat Tutanç

Abstract

Amaç: Obezite, artmış kan hacmi ve sol ventrikül hipertrofisi ile ilişkili ciddi bir durum olup, çocukluk çağında özellikle diyastolik disfonksiyon belirgin iken, yetişkinlikte daha yaygın olarak sistolik disfonksiyon gözlenir. Bu çalışmanın amacı, obez adolesanlarda vücut kitle indeksi, bel/kalça oranı ile kalpteki yapısal değişiklikler ve sistolik ile diyastolik fonksiyonlar arasındaki ilişkiyi incelemektir.
Gereç ve Yöntem: Çalışmaya 12-18 yaş arasındaki 80 obez ve 60 normal kilolu sağlıklı adolesan dahil edilmiştir. Tüm katılımcıların vücut kitle indeksi hesaplanmış ve sistolik ile diyastolik kan basınçları ölçülmüştür. Obez adolesanların lipid profili ve insülin direnci değerlendirmesi yapılmış olup bel/kalça oranı hesaplanmıştır. Tüm katılımcılara kardiyak fonksiyonları değerlendirmek amacıyla M-mode ekokardiyografi, pulsed Doppler ve doku Doppler ekokardiyografi değerlendirmesi yapılmıştır.
Bulgular: Sonuçlar, obez adolesanlarda sistolik ve diyastolik kan basıncının kontrol grubuna göre daha yüksek olduğunu göstermiştir. Sol ventrikül kitle indeksi, epikardiyal yağ dokusu ve karotis intima-media kalınlığı da obez grupta daha yüksek bulunmuştur. Ayrıca diyastolik disfonksiyon belirteçlerinde anlamlı bir azalma tespit edilmiştir. Sistolik disfonksiyon gözlenmemiştir; ancak hem sistolik hem diyastolik disfonksiyonu yansıtan sol ventrikül Tei indeksi obez grupta anlamlı derecede yüksek bulunmuştur.
Sonuç: Bu çalışma, obez adolesanlarda semptomlar ortaya çıkmadan önce kardiyak disfonksiyonun tespit edilebileceğini göstererek erken müdahale için bir fırsat sunmaktadır.

Keywords

Obezite, Adolesan, Ekokardiyografik diyastolik disfonksiyon

Evaluation of ventricular geometry and cardiac functions in obese adolescents with echocardiography

Abstract

Objective: Obesity is a serious condition associated with increased blood volume and left ventricular hypertrophy, with diastolic dysfunction being particularly prominent during childhood. In adulthood, systolic dysfunction is more commonly observed. The aim of this study is to examine the relationship between body mass index (BMI), waist/hip ratio, and the structural changes in the heart, as well as systolic and diastolic functions, in obese adolescents.
Methods: The study included 80 obese and 60 normal-weight adolescents aged between 12-18 years. The body mass index (BMI) of all participants was calculated, and their systolic and diastolic blood pressures were measured. Lipid profile and insulin resistance assessments were conducted for the obese adolescents, and waist/hip ratio was calculated. M-mode echocardiography, pulsed Doppler, and tissue Doppler echocardiography were performed on all subjects to evaluate cardiac functions.
Results: The results showed that systolic and diastolic blood pressure were higher in obese adolescents compared to the control group. Left ventricular mass index (LVMI), epicardial adipose tissue (EAT), and carotid intima-media thickness (CIMT) were also found to be higher in the obese group. Additionally, a significant decrease was detected in markers of diastolic dysfunction. No systolic dysfunction was observed; however, the left ventricular Tei index (LVTEI), which reflects both systolic and diastolic dysfunction, was significantly higher in the obese group.
Conclusion: This study demonstrates that cardiac dysfunction can be detected in obese adolescents before symptoms appear, providing an opportunity for early intervention

Keywords

Obesity, Adolescent, Echocardiography diastolic disfunction

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