Evaluation of Antifungal Potentials and Antioxidant Capacities of Some Foliose Lichen Species

Yıl 2018, Cilt: 22 Sayı: 1, 148 - 152, 17.03.2018

Bahar Bilgin Sökmen , Kadir Kınalıoğlu , Sinem Aydın

https://doi.org/10.19113/sdufbed.43724

Cited By: 1

Öz

This work is aimed to assess of antioxidant and antifungal potential of the foliose lichen species: Flavoparmelia caperata, Xanthoparmelia stenophylla and Xanthoparmelia conspersa. The antifungal activity of lichens were studied against some pathogenic fungi by disc diffusion method. The acetonitrile extracts of these lichens were obtained with Soxhlet extraction. While F. caperata exhibited maximum antifungal activity (32 mm) against the C. albicans, the minimum antifungal activity (10 mm) was obtained from X. stenophylla lichen against S. cerevisiae. In CUPRAC assay, absorbance values was in order of BHT>X. conspersa>F. caperata>X. stenophylla. As a result of the study, it was concluded that these lichen species may be a potential source for the development of new antifungal and antioxidant compounds.

Anahtar Kelimeler

Antioxidant activity, Lichen; Antifungal

Kaynakça

• [1] Lin, K., Yeh, H., Lin, S., Yang, C., Tsai, H., Tsai, J., Chao, P. 2014. Antioxidant Activities of Methanol Extracts from Selected Taiwanese Herbaceous Plants. Journal of Food Nutrition and Research, 2 (2014), 435-442.
• [2] Wu, T. W., Lee, C. C., Hsu, W. H., Hengel, M., Shibamoto, T. 2017. Antioxidant Activity of Natural Plant Extracts from Mate (Ilex paraguariensis), Lotus Plumule (Nelumbo nucifera Gaertn.) and Rhubarb (Rheum rhabarbarum L.) https: //www.scitechnol.com/peer-review/antioxidant-activity-of-natural-plant-extracts-from-mate-ilex-paraguariensis-lotus-plumule-nelumbo-nucifera-gaertn-and-rhubarb-rhe-OdpB.php ? article_ id=6259. (Erişim Tarihi: 15 Haziran 2017).
• [3] Aqil, F., Zahin, M., Ahmad, I., Khan, M., 2010. Combating Fungal Infections, Problems and Remedy. Springer-Verlag Berlin Heidelberg, 505 s.
• [4] Prince, L., Prabakaran, P. 2011. Antifungal Activity of Medicinal Plants Against Plant Pathogenic Fungus Colletotrichum falcatum. Asian Journal of Plant Science and Research, 1 (2011), 84-87.
• [5] Millot, M., Girardot, M., Dutreix, L., Mambu, L., Imbert, C. 2017. Antifungal and Anti-Biofilm Activities of Acetone Lichen Extracts against Candida albicans, Molecules, 22(2017), 651- 662.
• [6] Crawford, S. D. 2015. Lichens Used in Traditional Medicine. (In: B. Rankovic, Lichen Secondary Metabolites. Bioactive Properties and Pharmaceutical Potential). Springer International Publishing, Switzerland, p. 202.
• [7] Kosanic, M., Rankovic, B., Stanojkovic, T. 2013. Investigation of Selected Serbian Lichens for Antioxidant, Antimicrobial and Anticancer Properties. The Journal of Animal and Plant Sciences, 23(2013), 1628- 1633.
• [8] Brodo, I.M., Sharnoff, S. D., Sharnoff, S. 2001. Lichens of North America, Yale University Press, London, 771 s.
• [9] Smith, C. W., Aptroot, A., Coppins, B. J., Fletcher, A., Gilbert, O. L., James, P. W., Wolseley, P. A. 2009. The Lichens of Great Britain and Ireland, British Lichen Society, London, 2009, 1046 s.
• [10] Uphof, J. C. T. 1959. Dictionary of Economic Plant, Hafner Press, New York, 266 s.
• [11] Rankovic, B. 2015. Lichen Secondary Metabolites: Bioactive Properties and Pharmaceutical Potential. Springer International Publishing, Switzerland, p. 202.
• [12] Haq, M. U., Reshi, Z. A., Upreti, D. K., Sheikh, M. A. 2012. Lichen Wealth of Jamnu and Kashmir‐ A Promosing Plant Source for Bioprospection. Life Science Journal, 9(2012), 926‐929.
• [13] Kumar, S., Dhankhar, S., Arya, V. P., Yadav, S., Yadav, J. P. 2012. Antimicrobial Activity of Salvodora oleoides Decne. Against Some Microorganisms. Journal of Medicinal Plants, 6(2012), 2754-2760.
• [14] Santhanam, J., Abd Ghani, F.N., Basri, D.F. 2014. Antifungal Activity of Jasminum sambac against Malessezia sp. and Non-Malessezia sp. Isolated from Human Skin Samples. https://www.hindawi.com/journals/jmy/2014/359630/cta/ (Erişim Tarihi: 14.12.2017].
• [15] Uçan, F. 2008. DL-Limonenin Mayalar Üzerine Antifungal Etkisi. http://library. cu. edu.tr /tezler/6598.pdf (Erişim Tarihi: 10.07.2016).
• [16] Ertürk, Ö. 2006. Antibacterial and Antifungal Activity of Ethanolic Extracts from Eleven Spice Plants. Biologia Bratislava, 61 (2006), 275-278.
• [17] Özyürek, M., Bektaşoğlu, B., Güçlü, K., Apak, R. 2009. Measurement of Xanthine Oxidase Inhibition Activity of Phenolics and Flavonoids with a Modified Cupric Reducing Antioxidant Capacity (CUPRAC) Method. Analytica Chimica Acta, 636 (2009), 42-50.
• [18] Dharmadhikari, M., Jite, P.K., Chettiar, S., 2010. Antimicrobial Activity of Extracts of The Lichen and Its Isolated Mycobiont Parmelinella simplicior. Asian Journal of Experimental Biological Sciences Supplement, 54-58.
• [19] Mitrovic, T., Stamenkovic, S., Cvetkovic, V., Tosic, S., Stankovic, M., Radojevic, I., Stefanovic, O., Comic, L., Dacic, D., Curcic, M., Markovic, S. 2011. Antioxidant, Antimicrobial and Antiproliferative Activities of Five Lichen Species. International Journal of Molecular Sciences, 12 (2011), 5428-5448.
• [20] Srivastava, P., Logesh, A.R., Upreti, D.K., Dhole, T.N., Srivastava, A. 2013. In Vitro Evaluation of Some Indian Lichens Against Human Pathogenic Bacteria. Mycosphere, 4(2013), 734‐743.
• [21] Halama, P., Haluwin, C.V. 2004. Antifungal Activity of Lichen Extracts and Lichenic Acids. Biocontrol, 49(2004), 95-107.
• [22] Tiwari, P., Rai, H., Upreti, D.K., Trivedi, S., Shukla, P. 2011. Assestment of Antifungal Activity of Some Himalayan Foliose Lichens Against Plant Pathogenic Fungi. American Journal of Plant Sciences, 2(2011), 841-846.
• [23] Piovani, M., Garbarino, J.A., Giannii, F.A., Correche, E.R., Feresin, G., Topia, A., Zacchino, S., Enriz, R.D. 2002. Evaluation of Antifungal and Antibacterial Activities of Aromatic Metabolites from Lichens. Boletin De La Sociedad Chilenade Quimica, 47(2002), 235-240.
• [24] Cankılıç, M.Y., Sarıözlü, N.Y., Candan, M., Tay, T. 2017. Screening of Antibacterial, Antituberculosis and Antifungal Effects of Lichen Usnea florida and Its Thamnolic Acid Constituents. Biomedical Research, 28(2017), 3108-3113.
• [25] Özyürek, M., Güçlü, K., Apak, R. 2011. The Main and Modified CUPRAC Methods of Antioxidant Measurement. TrAC Trends in Analytical Chemistry, 30(2011), 652-664.
• [26] Stef, D., Iosif, G., Ioan, T. T., Stef, L., Pop, C., Harmanescu, M, Biron, R., Pet, E. 2010. Evaluation of 33 Medicinal Plant Extracts for th*e Antioxidant Capacity and Total Phenols. Journal of Food, Agriculture & Environment, 8(2010), 207-210.
• [27] Ganesan, A., Purushathaman, D.K., Muralitharan, U., Subbaiyan R. 2017. Metabolite Profiling and In Vitro Assessment of Antimicrobial and Antioxidant Activities of Lichen Ramalina inflate. International Research Journal of Pharmacy, 7(2017), 132-137.
• [28] Sundararaj, J.P., Kuppuraj, S., Ganesan, A., Ponnusamy, P., Nayaka, S. 2015. In Vitro Assessment of Antioxidant and Antimicrobial Activities of Different Solvent Extracts from Lichen Ramalina nervulosa. International Journal of Pharmacy and Pharmaceutical Sciences, 7(2015): 200-204.
• [29] Zlatonovic, I., Stankovic, M., Jovanovic, V.S., Mitic, V., Zrnzevic, I., Dordevic, A., Stajanovic, G. 2017. Biological Activities of Umbilicaria crustulosa (Ach.) Frey Acetone Extract. Journal of The Serbian Chemical Society, 82(2017), 141-150.