Olgu Sunumu
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Yetersiz Biyopsi Sonrası Yanlış Yorumlanan Ameloblastik Fibro-Odontoma Vakası: Olgu Sunumu

Yıl 2020, Cilt: 11 Sayı: 2, 282 - 286, 15.06.2020

Öz

Amaç: Ameloblastik fibro-odontoma (AFO) epitelyal ve mezenşimal hücrelerin proliferasyonu sonucu oluşan, nadir görülen, iyi huylu odontojenik bir tümördür. Genellikle çocuklarda görülür ve asemptomatik seyirlidir. AFO sınıflandırma bakımından aynı grupta bulunan diğer lezyonlara benzer özellikler taşımaktadır. Sunduğumuz olguda da eksik biyopsi sonucu yanlış teşhis konulan AFO vakası sunulmakta ve lezyonun histopatolojik olarak ayırıcı teşhisinde biyopsi örneklerinin eksiksiz alınmasının önemi vurgulanmaktadır.

Olgu: Sağ mandibular posterior bölgesinde geçmeyen şişlik şikayetiyle kliniğimize başvuran 9 yaşındaki erkek hastada öncelikle biyopsi yapılmasına karar verildi ve ardından kitlenin teşhisi Ameloblastik Fibroma (AF) olarak konuldu. Ancak lezyonun cerrahi eksizyonu sonucu yapılan ikinci histopatolojik incelemede kitlenin AFO olduğu rapore edildi. Hastanın postoperatif dönemde yapılan kontrollerinde ise iyileşmenin sorunsuz olduğu görüldü ve herhangi bir nüksle karşılaşılmadı.

Sonuç: AFO’nın literatürde odontomanın farklı bir safhası mı yoksa farklı bir patoloji mi olduğu konusunda da tartışmalar bulunmaktadır. Kesin teşhis için histopatolojik incelemenin dikkatle yapılması gerekmektedir. Ancak biyopsi kesitlerinin eksiksiz olması vakamızda karşılaştığımız gibi histopatolojik açıdan yanlış yorumlamaların önene geçecektir.

Destekleyen Kurum

Bulunmamaktadır.

Kaynakça

  • Cohen DM, Bhattacharyya I. Ameloblastic fibroma, ameloblastic fibro‑odontoma, and odontoma. Oral Maxillofac Surg Clin North Am. 2004;16:375‑384.
  • Barnes L, Eveson JW, Reichart P, et al. (eds) World Health Organization classification of tumours: pathology and genetics of head and neck tumours. Lyon: IARC Press, 2005.
  • Pontes HAR, Pontes FSC, Lamerira AG, Salim RA, Carvalho PL, Guimarães DM, et al. Report of four cases of ameloblastic fibro-odontoma in mandible and discussion of the literature about the treatment. J Craniomaxillofac Surg. 2012;40:e59-e63.
  • Martinez Martinez M, Romero CS, Pina AR, Palma Guzmán JM, de Almeida OP. Pigmented amelobalstic fibro-odontoma: clinical, histological, and immunohistochemical profile. Int J Surg Pathol. 2015;23:52-60.
  • Phillips MD, Closmann JJ, Baus MR, Torske KR, Williams SB. Hybrid odontogenic tumor with features of ameloblastic fibro-odontoma, calcifying odontogenic cyst, and adenomatoid odontogenic tumor: a case report and review of the literature. J Oral Maxillofac Surg. 2010;68:470-474.
  • Philipsen HP, Reichart PA, Praetorius F. Mixed odontogenic tumours and odontomas. Considerations on interrelationship. Review of the literature and presentation of 134 new cases of odontomas. Oral Oncol. 1997;33:86-99.
  • Tomich CE. Benign mixed odontogenic tumors. Semin Diagn Pathol. 1999; 16: 308-316.
  • Slootweg PJ. An analysis of the interrelationship of mixed odontogenic tumors-ameloblastic fibroma, ameloblastic fibro-odontoma, and the odontomas. Oral Surg Oral Med Oral Pathol. 1981;51:266-276.
  • Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and Maxillofacial Pathology. New York: NY: Elsevier; 2009.
  • Mosqueda-Taylor A. New findings and controversies in odontogenic tumors. Med Oral Patol Cir Buccal. 2008;13:e55.
  • Chrcanovic BR, Gomez RS. Ameloblastic fibrodentinoma and ameloblastic fibro‑odontoma: An updated systematic review of cases reported in the literature. J Oral Maxillofac Surg. 2017;75:1425‑1437.
  • Lee J, Song YG, Moon SY, Choi B, Kim BC, Yoon JH. Calcifying cystic odontogenic tumor associated with ameloblastic fibro-odontoma of the anterior mandible. J Craniofac Surg. 2014;25:e259-260.
  • Oghli AA, Scuto I, Ziegler C, Flechtenmacher C, Hofele C. Ameloblastic fibro-odontoma: A large ameloblastic fibro-odontoma of the right mandible. Med Oral Patol Oral Cir Bucal. 2007;12:E34-37.
  • Gardner DG. The mixed odontogenic tumors. Oral Surg Oral Med Oral Pathol. 1984;58:166‑168.
  • Zouhary KJ, Said-Al-Naief N, Waite PD. Ameloblastic fibro-odontoma: expansile mixed radiolucent lesion in the posterior maxilla: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106:e15-21.
  • Baker WR, Swift JQ. Ameloblastic fibro-odontoma of the anterior maxilla. Report of a case. Oral Surg Oral Med Oral Pathol. 1993;76:294-297.
  • Boxberger NR, Brannon RB, Fowler CB. Ameloblastic fibro-odontoma: a clinicopathologic study of 12 cases. J Clin Pediatr Dent. 2011;35:397-404.
  • Chen Y, Wang JM, Li TJ. Ameloblastic fibroma: a review of published studies with special reference to its nature and biological behavior. Oral Oncology. 2007;43:960-969.
  • Buchner A, Kaffe I, Vered M. Clinical and radiological profile of ameloblastic fibro‑odontoma: An update on an uncommon odontogenic tumor based on a critical analysis of 114 cases. Head Neck Pathol. 2013;7:54‑63.
  • Surej Kumar LK, Manuel S, Khalam SA, Venugopal K, Sivakumar TT, Issacc J. Ameloblastic fibro‑odontoma. Int J Surg Case Rep. 2014;5:1142‑1144.
  • Chrcanovic BR, Brennan PA, Rahimi S, Gomez RS. Ameloblastic fibroma and ameloblastic fibrosarcoma: a systematic review. J Oral Pathol Med. 2018;47:315-325.
  • Dolanmaz D, Pampu AA, Kalayci A, Etöz OA, Atici S. An unusual size of ameloblastic fibro-odontoma. Dentomaxillofac Radiol. 2008;37:179-182.
  • Chang H, Precious DS, Shimizu MS. Ameloblastic fibro-odontoma: A case report. J Can Dent Assoc. 2002;68:243-246.
  • Pereira KD, Bennett KM, Elkins TP, Qu Z. Ameloblastic fibroma of the maxillary sinus. Int J Pediatr Otorhinolaryngol. 2004;68:1473-1477.
  • Santos TDS, de Carvalho RWF, Avelar RL, Frota R, Anjos ED. Ameloblastic fibro-odontoma in children: report of 2 cases. J Dent Child. 2011;78:173-177.
  • al-Sebaei MO, Gagari E. Ameloblastic fibro-odontoma. J Mass Dent Soc. 2001;50:52-53.
  • Silva GCC, Jham BC, Silva EC, Horta MCR, Godinho SHP, Gomez RS. Ameloblastic fibro-odontoma. Oral Oncol Extra. 2006;42:217-220.
  • Rao AJP, Reddy M, Mahanthi VL, Chalapathi KV. Ameloblastic fibro-odontoma in a 14 year old girl: A case report. J Can Res Ther. 2019;15:715.
  • De Riu G, Meloni SM, Contini M, Tullio A. Ameloblastic fibro-odontoma. Case report and review of the literature. J Craniomaxillofac Surg. 2010;38:141-144.
  • Generali L, Giannetti L, Bellini P, Consolo U. Enucleazione conservativa di un fibro-odontoma ameloblastico. Italian Oral Surgery. 2007;4:45-50.
  • Friedrich RE, Siegert J, Donath k, Thorsten Jakel K. Recurrent Ameloblastic Fibro-odontoma in a 10-year-Old Boy. J Oral Maxillofac Surg. 2001;59:1362-1366.

Ameloblastic Fibro-Odontoma Misinterpreted Histopathologically After Insufficient Biopsy: A Case Report

Yıl 2020, Cilt: 11 Sayı: 2, 282 - 286, 15.06.2020

Öz

Objective: Ameloblastic fibro-odontoma (AFO) is a rare benign odontogenic tumor caused by proliferation of epithelial and mesenchymal cells. It is generally seen in children and has an asymptomatic course. In terms of classification, AFO has similar features to other lesions in the same group. In our case, the case of AFO which was misdiagnosed as a result of incomplete biopsy is presented and in the histopathological differential diagnosis of the lesion, the importance of taking biopsy samples completely is emphasized.

Case: A 9-year-old male patient who applied to our clinic with a complaint of swelling that did not pass in the right mandibular posterior region was decided to take a biopsy first, and then the diagnosis of the mass was made as Ameloblastic Fibroma (AF). However, in the second histopathological examination performed as a result of surgical excision of the lesion, the mass was reported to be AFO. In the patient's postoperative controls, healing was observed to be smooth and no recurrence was encountered.

Conclusion: There are also discussions in the literature about whether AFO is a different stage of odontoma or a different pathology. Histopathological examination should be done carefully for a definitive diagnosis. However, as in our case, biopsy sections should be performed completely to prevent histopathological misinterpretations.

Kaynakça

  • Cohen DM, Bhattacharyya I. Ameloblastic fibroma, ameloblastic fibro‑odontoma, and odontoma. Oral Maxillofac Surg Clin North Am. 2004;16:375‑384.
  • Barnes L, Eveson JW, Reichart P, et al. (eds) World Health Organization classification of tumours: pathology and genetics of head and neck tumours. Lyon: IARC Press, 2005.
  • Pontes HAR, Pontes FSC, Lamerira AG, Salim RA, Carvalho PL, Guimarães DM, et al. Report of four cases of ameloblastic fibro-odontoma in mandible and discussion of the literature about the treatment. J Craniomaxillofac Surg. 2012;40:e59-e63.
  • Martinez Martinez M, Romero CS, Pina AR, Palma Guzmán JM, de Almeida OP. Pigmented amelobalstic fibro-odontoma: clinical, histological, and immunohistochemical profile. Int J Surg Pathol. 2015;23:52-60.
  • Phillips MD, Closmann JJ, Baus MR, Torske KR, Williams SB. Hybrid odontogenic tumor with features of ameloblastic fibro-odontoma, calcifying odontogenic cyst, and adenomatoid odontogenic tumor: a case report and review of the literature. J Oral Maxillofac Surg. 2010;68:470-474.
  • Philipsen HP, Reichart PA, Praetorius F. Mixed odontogenic tumours and odontomas. Considerations on interrelationship. Review of the literature and presentation of 134 new cases of odontomas. Oral Oncol. 1997;33:86-99.
  • Tomich CE. Benign mixed odontogenic tumors. Semin Diagn Pathol. 1999; 16: 308-316.
  • Slootweg PJ. An analysis of the interrelationship of mixed odontogenic tumors-ameloblastic fibroma, ameloblastic fibro-odontoma, and the odontomas. Oral Surg Oral Med Oral Pathol. 1981;51:266-276.
  • Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and Maxillofacial Pathology. New York: NY: Elsevier; 2009.
  • Mosqueda-Taylor A. New findings and controversies in odontogenic tumors. Med Oral Patol Cir Buccal. 2008;13:e55.
  • Chrcanovic BR, Gomez RS. Ameloblastic fibrodentinoma and ameloblastic fibro‑odontoma: An updated systematic review of cases reported in the literature. J Oral Maxillofac Surg. 2017;75:1425‑1437.
  • Lee J, Song YG, Moon SY, Choi B, Kim BC, Yoon JH. Calcifying cystic odontogenic tumor associated with ameloblastic fibro-odontoma of the anterior mandible. J Craniofac Surg. 2014;25:e259-260.
  • Oghli AA, Scuto I, Ziegler C, Flechtenmacher C, Hofele C. Ameloblastic fibro-odontoma: A large ameloblastic fibro-odontoma of the right mandible. Med Oral Patol Oral Cir Bucal. 2007;12:E34-37.
  • Gardner DG. The mixed odontogenic tumors. Oral Surg Oral Med Oral Pathol. 1984;58:166‑168.
  • Zouhary KJ, Said-Al-Naief N, Waite PD. Ameloblastic fibro-odontoma: expansile mixed radiolucent lesion in the posterior maxilla: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106:e15-21.
  • Baker WR, Swift JQ. Ameloblastic fibro-odontoma of the anterior maxilla. Report of a case. Oral Surg Oral Med Oral Pathol. 1993;76:294-297.
  • Boxberger NR, Brannon RB, Fowler CB. Ameloblastic fibro-odontoma: a clinicopathologic study of 12 cases. J Clin Pediatr Dent. 2011;35:397-404.
  • Chen Y, Wang JM, Li TJ. Ameloblastic fibroma: a review of published studies with special reference to its nature and biological behavior. Oral Oncology. 2007;43:960-969.
  • Buchner A, Kaffe I, Vered M. Clinical and radiological profile of ameloblastic fibro‑odontoma: An update on an uncommon odontogenic tumor based on a critical analysis of 114 cases. Head Neck Pathol. 2013;7:54‑63.
  • Surej Kumar LK, Manuel S, Khalam SA, Venugopal K, Sivakumar TT, Issacc J. Ameloblastic fibro‑odontoma. Int J Surg Case Rep. 2014;5:1142‑1144.
  • Chrcanovic BR, Brennan PA, Rahimi S, Gomez RS. Ameloblastic fibroma and ameloblastic fibrosarcoma: a systematic review. J Oral Pathol Med. 2018;47:315-325.
  • Dolanmaz D, Pampu AA, Kalayci A, Etöz OA, Atici S. An unusual size of ameloblastic fibro-odontoma. Dentomaxillofac Radiol. 2008;37:179-182.
  • Chang H, Precious DS, Shimizu MS. Ameloblastic fibro-odontoma: A case report. J Can Dent Assoc. 2002;68:243-246.
  • Pereira KD, Bennett KM, Elkins TP, Qu Z. Ameloblastic fibroma of the maxillary sinus. Int J Pediatr Otorhinolaryngol. 2004;68:1473-1477.
  • Santos TDS, de Carvalho RWF, Avelar RL, Frota R, Anjos ED. Ameloblastic fibro-odontoma in children: report of 2 cases. J Dent Child. 2011;78:173-177.
  • al-Sebaei MO, Gagari E. Ameloblastic fibro-odontoma. J Mass Dent Soc. 2001;50:52-53.
  • Silva GCC, Jham BC, Silva EC, Horta MCR, Godinho SHP, Gomez RS. Ameloblastic fibro-odontoma. Oral Oncol Extra. 2006;42:217-220.
  • Rao AJP, Reddy M, Mahanthi VL, Chalapathi KV. Ameloblastic fibro-odontoma in a 14 year old girl: A case report. J Can Res Ther. 2019;15:715.
  • De Riu G, Meloni SM, Contini M, Tullio A. Ameloblastic fibro-odontoma. Case report and review of the literature. J Craniomaxillofac Surg. 2010;38:141-144.
  • Generali L, Giannetti L, Bellini P, Consolo U. Enucleazione conservativa di un fibro-odontoma ameloblastico. Italian Oral Surgery. 2007;4:45-50.
  • Friedrich RE, Siegert J, Donath k, Thorsten Jakel K. Recurrent Ameloblastic Fibro-odontoma in a 10-year-Old Boy. J Oral Maxillofac Surg. 2001;59:1362-1366.
Toplam 31 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm Olgu Sunumları
Yazarlar

Muhammed Yusuf Kurt 0000-0002-1360-276X

Bilal Ege 0000-0002-1279-0893

Ayşe Örmeci Bu kişi benim 0000-0002-4426-9787

Yayımlanma Tarihi 15 Haziran 2020
Gönderilme Tarihi 26 Şubat 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 11 Sayı: 2

Kaynak Göster

Vancouver Kurt MY, Ege B, Örmeci A. Yetersiz Biyopsi Sonrası Yanlış Yorumlanan Ameloblastik Fibro-Odontoma Vakası: Olgu Sunumu. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi. 2020;11(2):282-6.

SDÜ Sağlık Bilimleri Dergisi, makalenin gönderilmesi ve yayınlanması dahil olmak üzere hiçbir aşamada herhangi bir ücret talep etmemektedir. Dergimiz, bilimsel araştırmaları okuyucuya ücretsiz sunmanın bilginin küresel paylaşımını artıracağı ilkesini benimseyerek, içeriğine anında açık erişim sağlamaktadır.