Fruktoz tüketimi karotis arter hastalığı ile ilişkili olabilir

Yıl 2021, Cilt: 12 Sayı: 1, 50 - 56, 31.03.2021

Mevlüt Serdar Kuyumcu , Aliye Kuyumcu

https://doi.org/10.18663/tjcl.864019

Öz

Amaç: Yüksek fruktoz tüketiminin kardiyovasküler hastalıklar ile ilişkili olduğu bilinmektedir, fakat çalışmalar sınırlıdır. Bu çalışmanın amacı, karotis arter darlığı (KAD) ile yüksek früktoz tüketimi arasındaki ilişkiyi değerlendirmektir.
Gereç ve Yöntemler: Hastalar, KAD>60% olan (60 hasta), KAD <60% olan (60 hasta) ve karotis aterosklereotik hastalığı bulunmayan (60 hasta) olarak üç gruba ayrılmıştır. Hastaların geriye dönük 3 günlük besin tüketim kayıtlar alınmıştır. Veriler gruplar arasında karşılaştırılmıştır.
Bulgular: Fruktoz tüketimi, KAD<%60 olan hastalara göre normal bireylerde daha düşük bulunmuştur (p<0.001). Ayrıca, KAD>60% olanlara göre KAD<60% olanlarda frukotz tüketimi daha düşüktür. Çok değişkenli regresyon analizinde yüksek früktoz tüketimi 60% üzeri karotis stenozu için bağımsız risk faktörü olarak saptanmıştır (p<0.001).
Sonuç: Çalışmamızda KAD olan bireylerde früktoz tüketimi yüksek saptanmıştır. Çalışmamız artmış Fruktoz tüketiminin KAD’a etkisi olabileceğini gösteren literatürde ki ilk çalışmadır.

Anahtar Kelimeler

Karotis arter hastalığı, fruktoz, ateroskleroz

High fructose intake may be related to carotid artery stenosis

Öz

Aim: It is known that high fructose intake is related to cardiovascular diseases but there is a limited number of researches in this era. The objective of this research is to evaluate the relation between Carotid Artery Stenosis (CAS) and high fructose intake.
Material And Methods: The patients are categorized into three groups: Patients with CAS≥60% (60 patients), patients with CAS<60% (60 patients) and patients with no carotid atherosclerosis (60 patients). Nutrient intake level of patients is observed and recorded by 24-Hour Dietary Recall Forms and the intake frequency of high-fructose dietary is enquired. Physical activity levels are also evaluated. All the collected data is compared among the groups.
Results: Fructose intake among ordinary people is found to be lower than the patients with CAS<60% (p<0.001). Besides, fructose intake of patients with CAS<60% is lower than fructose intake of patients with CAS≥60%. Multivariate regression analysis showed that high fructose intake is an independent risk factor for carotid stenosis over 60% (p<0.001). Fructose intake levels were higher in the calcific plaque group than in the non-calcific plaque group (p<0.001).
Conclusions: We determined a high fructose intake in patients with CAS. In light of our research data, we consider high fructose intake to have a potential role in the pathophysiology of CAS.

Anahtar Kelimeler

Carotid artery stenosis, fructose, atherosclerosis

Kaynakça

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