INVESTIGATIONS OF 44Ti PRODUCTION FOR 44Ti/44Sc RADIONUCLIDE GENERATOR

Yıl 2022, Cilt: 34 Sayı: 1, 30 - 39, 07.07.2022

Buğra Gökhun Bulduk , Volkan Yasakçı , Elif Tutun , Perihan Ünak , Ömer Aras

Öz

44Sc is a promising PET radionuclide because of its short half-life of approximately 4 hours and its ability to emit positrons. In this work, a 44Ti/44Sc generator was designed to produce 44Sc. The separation and purification studies were optimized by using 46Sc as tracer. Hydroxamate and Dowex resins were used for separation process 46Sc from titanium. Briefly a 44Ti/44Sc generator system may be a source of 44Sc production in hospitals in future. If it is made suitable for hospital use, a hospital will have the opportunity to work with this generator for many years with a single production.

Anahtar Kelimeler

44Sc, 44Ti, 44Ti/44Sc generator, cyclotron, 45Sc(p,2n)44Ti, hydroxamate resin

Destekleyen Kurum

Ege Üniversitesi

Proje Numarası

FGA-2018-20118

Teşekkür

Buğra Gökhun Bulduk was supported by the TUBITAK 2211-C Priority Areas Domestic Doctorate Scholarship Program. Omer Aras was partially supported by the NIH/NCI Cancer Center Support Grant P30 CA008748.

Kaynakça

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