Monitoring of oxidative stress and TNF-α status during the healing process in hair goats with metritis

Yıl 2022, Cilt: 6 Sayı: 1, 15 - 18, 29.03.2022

Serdal Kurt , Funda Eşki , Leyla Mis

https://doi.org/10.47748/tjvr.1069768

Cited By: 1

Öz

Objective: This study aimed to monitor oxidative stress parameters including total antioxidant status (TAS) and total oxidant status (TOS), and tumor necrosis factor-alpha (TNF-α) level during the healing process in hair goats with metritis.
Materials and Methods: This study was carried out on a total of 25 hair goats with metritis (n=10; Group 1) and healthy (n=15; Group 2). The beginning of the study was accepted as day 0. In both Group 1 and Group 2, blood samples were collected on days 0 (first measurement day), 14 (second measurement day) and 28 (third measurement day) of the study for TAS, TOS and TNF-α analyzes. In addition, oksidatif stress index (OSI) was calculated using TAS and TOS values.
Results: It was found that TAS level decreased in Group 1 compared to Group 2 at the first measurement day (p<0.05). Howener, TOS, OSI and TNF-α levels increased in Group 1 compared to Group 2 (p<0.01). At the second measurement day, TOS and OSI values were higher in Group 1 than Group 2 (p<0.05).
Conclusion: In conclusion, the antioxidant system weakened, oxidative stress and TNF-α levels increased in animals with metritis compared to healthy animals. However, at the third measurement time, all parameters became similar between groups.

Anahtar Kelimeler

Hair goat, metritis, oksidative stress, TNF-α.

Kaynakça

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