ERİTROSİTLERDE in vitro OKSİDATİF STRESE KARŞI ANTİOKSİDAN OLARAK DEĞERLENDİRİLEN ÇEŞİTLİ BİTKİ EKSTRAKTLARI

Year 2017, Volume: 18 Issue: 2, 185 - 191, 02.08.2017

Seda Balkan

https://doi.org/10.23902/trkjnat.297800

Cited By: 2

Abstract

Son yıllarda pek çok hastalığın patogenezinde oksidatif stresin etken
olması araştırıcıların dikkatini çekmiştir. Eritrositler tüm vücut dokuları ve
organları ile iletişim halinde olan, oksidatif strese karşı en hassas hücre
gruplarından biridir. Bu nedenle oksidatif stresin olumsuz etkilerinin
belirlenmesi için yapılan çalışmalarda eritrosit hücreleri sıklıkla
kullanılmaktadır. Bununla birlikte oksidatif stresin olumsuz etkilerinin azaltılabilmesi
veya yok edilebilmesi için doğal kaynaklı antioksidan maddelerin arayışı ile
ilgili çalışma sayısı her geçen gün artmaktadır. Bu doğal kaynaklı antioksidan
maddelerin tespiti için yapılan çalışmalarda çoğunlukla bitki ekstraktlarından
yararlanılmakta ve bu ekstraktların antioksidan kapasiteleri araştırılmaktadır.
Bu çalışmada, eritrositlerde oksidatif stresin meydana getirilme yolları ve
oksidatif strese karşı kullanılan bitki ekstraktları ile ilgili bilgilere yer
verilmiştir.

Keywords

Bitki ekstraktı, oksidatif stres, eritrosit, in vitro

Various Plant Extracts Evaulated as Antioxidant Against in vitro Oxidative Stress in Erythrocytes

Abstract

The role of oxidative stress in pathogenesis of
many diseases has interested researchers in recent years. Erythrocytes are in
contact with all organs and tissues and are one of the most vulnerable cell
types against oxidative stress. Therefore, erythrocyte cells are commonly used
in studies performed to reveal negative effects of oxidative stress. On the
other hand, the number of studies carried out with the aim of finding natural
antioxidants to reduce or neutralize negative effects of oxidative stress is increasing
day by day. Plant extracts are mostly used in these studies and antioxidant
effects of these extracts are investigated. In the present study, current data
on the means of producing oxidative stress in erythrocytes and the plant
extracts used against oxidative stress were reviewed.

Keywords

Plant extract, oxidative stress, erythrocyte, in vitro

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