Effects of different doses of branched-chain amino acid supplementation on recovery following acute eccentric exercise

Yıl 2023, , 272 - 279, 30.12.2023

Şerife Vatansever , Raif Zileli , Serkan Pancar , Şenay Şahin , Yakup Zühtü Birinci , Huseyin Topçu

https://doi.org/10.31459/turkjkin.1355853

Öz

This study investigated the effect of different amounts of Branched-Chain Amino Acids (BCAA) supplementation on recovery from eccentric exercise. Nine healthy male subjects undertook 4 trials in a randomized crossover design. Participants ingested either a three different amount (2g, 10g, and 20g) of BCAA supplement or placebo before the eccentric exercise. Muscle pain, hunger, vertical jump, balance, and sprint performance were measured before exercise, immediately after exercise, 1, 24, and 48 h. after exercise. All the variables were checked regarding their normal distribution using the Shapiro-Wilk test and data were presented as means ±SD. A repeated-measure, two factor ANOVA was used to examine differences between the four trials over time for balance, speed, vertical jump, hunger, and muscle pain change. No differences were found at baseline values for balance, velocity, vertical jump, hunger, and muscle pain for four trials (p > 0.05). While the main effect of time was statistically significant for balance, speed, vertical jump, hunger, and muscle pain (p<0.05), the main effect of trial and the interaction effect (time*trial) were not statistically significant. It indicated that the measurements changed during the time, but not influenced by different doses of BCAA. In conclusion, there are no significant effects of different amounts of BCAA supplementation on recovery performance after acute eccentric exercise.

Anahtar Kelimeler

BCAA, sports nutrition, supplement, eccentric exercise, muscle damage, recovery

Kaynakça

• Baysal, A. (2011). Nutrition (p.70). Ankara; Hatipoğlu Press.
• Biolo, G., Tipton, K. D., Klein, S., & Wolfe, R. R. (1997). An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Am J Physiol Endocrinol Metab, 273(1),122-129.
• Brandner, C. R., & Warmington, S. A. (2017). Delayed onset muscle soreness and perceived exertion after blood flow restriction exercise. J Strength Cond Res, 31(11), 3101-3108.
• Damas, F., Phillips, S. M., Libardi, C. A., Vechin, F. C., Lixandrao, M. E., Jannig, P. R., & Tricoli, V. (2016). Resistance training‐induced changes in integrated myofibrillar protein synthesis are related to hypertrophy only after attenuation of muscle damage. The Journal of Physiology,594(18), 5209-5222.
• Dokumacı, B., & Çakır Atabek, H. (2016). Delayed onset muscle soreness and mechanisms: Relation with oxidative stress: Review. Turkiye Klinikleri Journal of Sports Sciences, 8(1), 22-34.
• Dorrell, H., & Gee, T. (2016). The acute effects different quantities of branched-chain amino acids have on recovery of muscle function. Sports Nutrition and Therapy,1(3),115-115.
• Draper, S. N., Kullman, E. L., Sparks, K. E., Little, K., & Thoman, J. (2020). Effects of intermittent pneumatic compression on delayed onset muscle soreness (DOMS) in long distance runners. International Journal of Exercise Science,13(2),75-86.
• Foure, A., Nosaka, K., Gastaldi, M., Mattei, J. P., Boudinet, H., Guye, M., Vilmen, C., Le Fur, Y., Bendahan, D., & Gondin, J. (2016). Effects of branched-chain amino acids supplementation on both plasma amino acids concentration and muscle energetics changes resulting from muscle damage: A randomized placebo controlled trial. Clin Nutr, 35, 83–94.
• Foure, A., & Bendahan, D. (2017). Is branched-chain amino acids supplementation an efficient nutritional strategy to alleviate skeletal muscle damage? A systematic review. Nutrients, 9(10), 1047.
• Greer, B. K., Woodard, J. L., White, J. P., Arguello, E. M., & Haymes, E. M. (2007). Branched-chain amino acid supplementation and indicators of muscle damage after endurance exercise. Int J Sport Nutr Exerc Metab, 17(6), 595-607.
• Gee, T. I., & Deniel, S. (2016). Branched-chain amino acid supplmentation attenuates a decrease in power-producing ability following acute srtength training. J Sports Med Phys Fitness, 56(12), 1511-1517.
• Guven, O., Ozdemir, G., & Ersoy, G. (2009). Determination of veteran athletes’ nutrition habits and nutrition knowledge in Ankara. Spormetre The Journal Of Physical Education and Sport Sciences, 7(3),125-133.
• Howatson, G., Hoad, M., Goodall, S., Tallent, J., Bell, P. G., & French, D. N. (2012). Exercise-induced muscle damage is reduced in resistance-trained males by branched chain amino acids: a randomized, double-blind, placebo controlled study. J Int Soc Sports Nutr, 9(1), 20.
• Hulmi, J. J., Lockwood, C. M., & Stout, J. R. (2010). Effect of protein/essential amino acids and resistance training on skeletal muscle hypertrophy: A case for whey protein. Nutr Metab, 7(1), 51.
• Impellizzeri, F. M., Rampinini, E., Castagna, C., Martino, F., Fiorini, S., & Wisloff, U. (2008). Effects of plyometric training on sand versus grass on muscle soreness and jumping and sprinting ability in soccer players. Br J Sports Med, 42, 42-46.
• Jackman, S. R., Witard, O. C., Jeukendrup, A. E., & Tipton, K. D. (2010). Branched-chain amino acid ingestion can ameliorate soreness from eccentric exercise. Med Sci Sports Exerc, 42(5), 962-970.
• Kirby, T. J., Triplett, N. T., Haines, T. L., Skinner, J. W., Fairbrother, K. R., & McBride, J. M. (2012). Effect of leucine supplementation on indices of muscle damage following drop jumps and resistance exercise. Amino Acids, 42, 1987–1996.
• Levenhagen, D. K., Gresham, J. D., Carlson, M. G., Maron, D. J., Borel, M. J., & Flakoll, P. J. (2001). Postexercise nutrient intake timing in humans is critical to recovery of leg glucose and protein homeostasis. Am J Physiol Endocrinol Metab, 280(6), 982-993.
• Manzo, M. (2017). The effect of BCAA supplementation on mental performance following exercise. Sacred Heart University. Academic Festival, 66.
• Nosaka, K., Sacco, P., & Mawatari, K. (2006). Effects of amino acid supplementation on muscle soreness and damage. Int J Sport Nutr Exerc Metab, 16(6), 620-635.
• Pancar, S., Vatansever, Ş., & Birinci, Y. Z. (2018). The effect of BCAAs on mental performance after exercise. Scholars Journal of Arts, Humanities and Social Sciences, 6(12), 2269-2274.
• Ra, S.G., Miyazaki, T., Kojima, R., Komine, S., Ishikura, K., Kawanaka, K, Hond, A., Matsuzaki, Y., & Ohmori, H. (2018). Effect of BCAA supplement timing on exercise-induced muscle soreness and damage: a pilot placebo-controlled double-blind study. J Sports Med Phys Fitness, 58(11), 1582-1591.
• Ratamess, N. A., Kraemer, W. J., Volek, J. S., Rubin, M. R., Gomez, A. L., French, D. N., & Newton, R. U. (2003). The effects of amino acid supplementation on muscular performance during resistance training overreaching. J Strength Cond Res, 17(2), 250-258.
• Rennie, M. J. (2001). Control of muscle protein synthesis as a result of contractile activity and amino acid availability: Implications for protein requirements. Int J Sport Nutr Exerc Metab, 11(1), 170-176.
• Schoenfeld, B. J. (2010). The mechanisms of muscle hypertrophy and their application to resistance training. J Strength Cond Res, 24(10), 2857-2872.
• Shimomura, Y., Murakami, T., Nakai, N., Nagasaki, M., & Harris, R. A. (2004). Exercise promotes BCAA catabolism: Effects of BCAA supplementation on skeletal muscle during exercise. J Nutr, 134(6), 1583-1587.
• Shimomura,Y., Inaguma, A., Watanabe, S., Yamamoto, Y., Muramatsu, Y., Bajotto, G., & Mawatari, K. (2010). Branched-chain amino acid supplementation before squat exercise and delayed-onset muscle soreness. Int J Sport Nutr Exerc Metab, 20(3), 236-244.
• Stark, M., Lukaszuk, J., Prawitz, A., & Salacinski, A. (2012). Protein timing and its effects on muscular hypertrophy and strength in individuals engaged in weight-training. J Int Soc Sports Nutr, 9(1), 54.
• Tipton, K. D., & Wolfe, R. R. (1998). Exercise‐induced changes in protein metabolism. Acta Psychiatr Scand, 162(3), 377-387.
• Tipton, K. D., Rasmussen, B. B., Miller, S. L., Wolf, S. E., Owens-Stovall, S. K., Petrini, B. E., & Wolfe, R. R. (2001). Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am J Physiol Endocrinol Metab, 281(2), 197-206.
• Vatansever, S., Sonmez-Tiryaki, G., Bugdayci, G., & Ozen, G. (2011). The effects of exercise on food intake and hunger: Relationship with acylated ghrelin and leptin. J Sports Sci Med, 10, 283–291.
• Van Dusseldorp, T. A., Escobar, K. A., Johnson, K. E., Stratton, M. T., Moriarty, T., Cole, N., McCormick, J. J., Kerksick, C. M., Vaughan, R. A., Doklandy, K., Kravitz, L., & Mermier, C. M. (2018). Effect of branched-chain amino acid supplementation on recovery following acute eccentric exercise. Nutrients, 10, 1389.
• Wolfe, R.R. (2000). Protein supplements and exercise. Am J Clin Nutr, 72(2), 551-557.