The Relationship Between Pain Distress Severity and Fatigue Levels of Women with Breast Cancer Receiving Chemotherapy: A Descriptive Cross-sectional Study

Yıl 2023, Cilt: 49 Sayı: 2, 221 - 229, 08.09.2023

Pınar Zorba Bahçeli , Ayşe Arıkan Dönmez , Gamze Ünver , Sevgisun Kapucu

https://doi.org/10.32708/uutfd.1299065

Cited By: 1

Öz

The objective of this study was to determine the relationship between pain distress and fatigue levels in women with breast cancer receiving chemotherapy. The descriptive and cross-sectional study was completed with 147 women with breast cancer receiving chemotherapy who came to the outpatient Chemo unit of a state university oncology hospital. Research data were collected by the researchers using face-to-face Descriptive Information Form, Visual Analog Scale, Brief Fatigue Inventory, and Pain Distress Inventory. The results showed that 61.9% of the women stated that they used drugs for pain, and 38.8% of them stated that they used paracetamol group drugs for pain. It was determined that there was a significant difference between the Brief Fatigue Inventory sub-dimension and total score averages of the participants and the type of surgery, medication use for pain, and type of medication used for pain. It was determined that there was a significant difference between the patients' Pain Distress Inventory sub-dimension and total score averages and their use of drugs for pain, the type of drug used for pain, and the conditions that increase pain. It was determined that there was a weak positive correlation between the total score of Brief Fatigue Inventory and the total score of Brief Fatigue Inventory. In our study, it was determined that women with breast cancer who received chemotherapy experienced moderate fatigue and pain distress, and pain distress severity and fatigue were associated with each other. It is recommended that nurses include interventions to effectively manage pain distress and fatigue for women with breast cancer in their care plans for their patients.

Anahtar Kelimeler

Pain distress, chemotherapy, breast cancer, fatigue

Proje Numarası

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Kemoterapi Alan Meme Kanserli Kadınların Ağrı Distresi Şiddeti ve Yorgunluk Düzeyleri Arasındaki İlişki: Tanımlayıcı Kesitsel Bir Çalışma

Öz

Bu çalışmada kemoterapi alan meme kanserli kadınlarda ağrı distresi ile yorgunluk düzeyleri arasındaki ilişkinin belirlenmesi amaçlanmıştır. Tanımlayıcı ve kesitsel tipte yapılan çalışma bir devlet üniversitesinin onkoloji hastanesinin ayaktan kemoterapi ünitesine tedavi almak için gelen 147 meme kanserli kadın hasta ile tamamlandı. Araştırma verileri, araştırmacılar tarafından yüzyüze Tanıtıcı Bilgi Formu, Görsel Analog Skala, Kısa Yorgunluk Envanteri ve Ağrı Distres Envanteri kullanılarak toplandı. Kadınların %61.9’u ağrı nedeniyle ilaç kullandığını, %38.8’inin ise ağrı için parasetamol grubu ilaç kullandığını belirtti. Katılımcıların Kısa Yorgunluk Envanteri alt boyut ve toplam puan ortalamaları ile ameliyat türü, ağrı için ilaç kullanma durumu ve ağrı için kullanılan ilaç türü arasında anlamlı fark olduğu belirlendi. Hastaların Ağrı Distres Envanteri alt boyut ve toplam puan ortalamaları ile ağrı için ilaç kullanma durumu, ağrı için kullanılan ilaç türü ve ağrıyı artıran durumlar arasında anlamlı fark olduğu belirlendi. Kısa Yorgunluk Envanteri toplam puanı ile Ağrı Distres Envanteri toplam puanı arasında pozitif yönde anlamlı zayıf bir ilişki olduğu belirlendi. Çalışmamızda, kemoterapi alan meme kanserli kadınlarda orta şiddette yorgunluk ve ağrı distresi yaşadıkları ve ağrı distresi şiddeti ve yorgunluk durumunun birbiri ile ilişkili olduğu belirlendi. Hemşirelerin hastalarına yönelik hazırladıkları bakım planlarında, meme kanserli kadınlara ağrı distresi ve yorgunluğu etkili bir şekilde yönetilebilmelerine ilişkin girişimlere de yer vermeleri önerilmektedir.

Anahtar Kelimeler

Ağrı distresi, kemoterapi, meme kanseri, yorgunluk

Destekleyen Kurum

yok

Proje Numarası

-

Teşekkür

Çalışmaya katılmayı kabul eden, duygu-düşüncelerini içtenlikle ifade eden hastalarımıza teşekkür ederiz.

Kaynakça

• 1. Giaquinto AN, Sung H, Miller KD, et al. Breast Cancer Statistics, 2022. CA Cancer J Clin. 2022;72(6):524-541. doi:10.3322/caac.21754
• 2. Centers for Disease Control and Prevention. How Is Breast Cancer Treated? Published September 26, 2022. Accessed April 10, 2023. https://www.cdc.gov/cancer/breast/basic_info/treatment.htm
• 3. Bjerkeset E, Röhrl K, Schou-Bredal I. Symptom cluster of pain, fatigue, and psychological distress in breast cancer survivors: prevalence and characteristics. Breast Cancer Res Treat. 2020;180(1):63-71. doi:10.1007/s10549-020-05522-8
• 4. Fisher HM, Hyland KA, Winger JG, et al. Effect of Pain Coping Skills Training on Pain and Pain Medication Use for Women with Breast Cancer. J Pain Symptom Manage. Published online April 2023. doi:10.1016/j.jpainsymman. 2023.03.012
• 5. Fox RS, Ancoli-Israel S, Roesch SC, et al. Sleep disturbance and cancer-related fatigue symptom cluster in breast cancer patients undergoing chemotherapy. Support Care Cancer. 2020;28(2):845-855. doi:10.1007/s00520-019-04834-w
• 6. Lam E, Wong G, Zhang L, et al. Self-reported pain in breast cancer patients receiving adjuvant radiotherapy. Support Care Cancer. 2021;29(1):155-167. doi:10.1007/s00520-020-05462-5
• 7. Slaghmuylder Y, Pype P, Van Hecke A, Lauwerier E. Development of an intervention aimed at the prevention and treatment of chronic pain in breast cancer survivors: An intervention mapping approach. Patient Educ Couns. 2023;108:107618. doi:10.1016/j.pec.2022.107618
• 8. Talwar A, Rege S, Aparasu RR. Pain management practices for outpatients with breast cancer. Explor Res Clin Soc Pharm. 2022;6:100155. doi:10.1016/j.rcsop.2022.100155
• 9. Costa WA, Monteiro MN, Queiroz JF, Gonçalves AK. Pain and quality of life in breast cancer patients. Clinics. 2017;72(12):758-763. doi:10.6061/clinics/2017(12)07
• 10. Johannsen M, Christensen S, Zachariae R, Jensen A. Socio-demographic, treatment-related, and health behavioral predictors of persistent pain 15 months and 7–9 years after surgery: a nationwide prospective study of women treated for primary breast cancer. Breast Cancer Res Treat. 2015;152(3):645-658. doi:10.1007/s10549-015-3497-x
• 11. Li X-M, Xiao W-H, Yang P, Zhao H-X. Psychological distress and cancer pain: Results from a controlled cross-sectional survey in China. Sci Rep. 2017;7(1):39397. doi:10.1038/srep39397
• 12. Hadlandsmyth K, Sabic E, Zimmerman MB, et al. Relationships among pain intensity, pain-related distress, and psychological distress in pre-surgical total knee arthroplasty patients: a secondary analysis. Psychol Health Med. 2017;22(5):552-563. doi:10.1080/13548506.2016.1189581
• 13. Yee MK, Sereika SM, Bender CM, Brufsky AM, Connolly MC, Rosenzweig MQ. Symptom incidence, distress, cancer-related distress, and adherence to chemotherapy among African American women with breast cancer. Cancer. 2017;123(11):2061-2069. doi:10.1002/cncr.30575
• 14. Mazanec SR, Park S, Connolly MC, Rosenzweig MQ. Factors associated with symptom distress in women with breast cancer prior to initiation of chemotherapy. Appl Nurs Res. 2021;62:151515. doi:10.1016/j.apnr.2021.151515
• 15. Bourmaud A, Anota A, Moncharmont C, et al. Cancer-related fatigue management: evaluation of a patient education program with a large-scale randomised controlled trial, the PEPs fatigue study. Br J Cancer. 2017;116(7):849-858. doi:10.1038/bjc.2017.31
• 16. Juvet LK, Thune I, Elvsaas IKØ, et al. The effect of exercise on fatigue and physical functioning in breast cancer patients during and after treatment and at 6 months follow-up: A meta-analysis. The Breast. 2017;33:166-177. doi:10.1016/j.breast.2017.04.003
• 17. Reinertsen K V., Engebraaten O, Loge JH, et al. Fatigue During and After Breast Cancer Therapy—A Prospective Study. J Pain Symptom Manage. 2017;53(3):551-560. doi:10.1016/j.jpainsymman.2016.09.011
• 18. Bower JE. Cancer-related fatigue—mechanisms, risk factors, and treatments. Nat Rev Clin Oncol. 2014;11(10):597-609. doi:10.1038/nrclinonc.2014.127
• 19. Huang H-P, Wen F-H, Yang T-Y, et al. The effect of a 12-week home-based walking program on reducing fatigue in women with breast cancer undergoing chemotherapy: A randomized controlled study. Int J Nurs Stud. 2019;99:103376. doi:10.1016/j.ijnurstu.2019.06.007
• 20. Liu D, Weng J-S, Ke X, Wu X-Y, Huang S-T. The relationship between cancer-related fatigue, quality of life and pain among cancer patients. Int J Nurs Sci. 2023;10(1):111-116. doi:10.1016/j.ijnss.2022.12.006
• 21. Faul F, Erdfelder E, Buchner A, Lang A. G∗ Power Version 3.1. 9.2. Published online 2014.
• 22. Hofsø K, Rustøen T, Cooper BA, Bjordal K, Miaskowski C. Changes Over Time in Occurrence, Severity, and Distress of Common Symptoms During and After Radiation Therapy for Breast Cancer. J Pain Symptom Manage. 2013;45(6):980-1006. doi:10.1016/j.jpainsymman.2012.06.003
• 23. Knudsenl AK, Brunellil C, Kaasal S, et al. Which variables are associated with pain intensity and treatment response in advanced cancer patients?- Implications for a future classification system for cancer pain. Eur J Pain. 2011;15(3):320-327. doi:10.1016/j.ejpain.2010.08.001
• 24. Pertl MM, Hevey D, Collier S, Lambe K, O’Dwyer A-M. Predictors of fatigue in cancer patients before and after chemotherapy. J Health Psychol. 2014;19(6):699-710. doi:10.1177/1359105313477675
• 25. Cacereni A. Evaluation and assessment of cancer pain and cancer pain treatment. Acta Anaesthesiol Scand. 2001;45:1067-1075.
• 26. Çöçelli- Pirbudak L, Bacaksız D, Ovayolu N. Ağrı tedavisinde hemşirenin rolü. Gaziantep Tıp Derg. 2008;14:53-58.
• 27. Eti-Aslan F. Ağrı ve değerlendirme yöntemleri. Cumhur Üniversitesi Hemşirelik Yüksekokulu Derg. 2002;6(1):9-16.
• 28. Noble B, Clark D, Meldrum M, et al. The measurement of pain, 1945–2000. J Pain Symptom Manage. 2005;29(1):14-21. doi:10.1016/j.jpainsymman.2004.08.007
• 29. Ong SK, Seymour A. Pain management in humans. Surg. 2004;2(2):15-27.
• 30. Mendoza TR, Wang XS, Cleeland CS, et al. The rapid assessment of fatigue severity in cancer patients. Cancer. 1999;85(5):1186-1196. doi:10.1002/(SICI)1097-0142(19990301)85:5<1186::AID-CNCR24>3.0.CO;2-N
• 31. Yesilbalkan ÖU, Karadakovan A, Göker E. The Effectiveness of Nursing Education as an Intervention to Decrease Fatigue in Turkish Patients Receiving Chemotherapy. Oncol Nurs Forum. 2009;36(4):E215-E222. doi:10.1188/09.ONF.E215-E222
• 32. Osman A, Barrios FX, Gutierrez PM, Kopper BA, Butler A, Bagge CL. The Pain Distress Inventory: Development and initial psychometric properties. J Clin Psychol. 2003;59(7):767-785. doi:10.1002/jclp.10173
• 33. Dedeli Ö, Fadıloğlu Ç, Uyar M. Kronik nonmalign ağrısı olan bireylerde bilişsel-davranışçı ağrı modeli’nin incelenmesi. MN Dahili Tıp Bilim Derg. 2008;3(4):232-242.
• 34. Ho PJ, Gernaat SAM, Hartman M, Verkooijen HM. Health-related quality of life in Asian patients with breast cancer: a systematic review. BMJ Open. 2018;8(4):e020512. doi:10.1136/bmjopen-2017-020512
• 35. Calderon C, Carmona-Bayonas A, Hernández R, et al. Effects of pessimism, depression, fatigue, and pain on functional health-related quality of life in patients with resected non-advanced breast cancer. The Breast. 2019;44:108-112. doi:10.1016/j.breast.2019.01.012
• 36. Schreier AM, Johnson LA, Vohra NA, Muzaffar M, Kyle B. Post-Treatment Symptoms of Pain, Anxiety, Sleep Disturbance, and Fatigue in Breast Cancer Survivors. Pain Manag Nurs. 2019;20(2):146-151. doi:10.1016/j.pmn.2018.09.005
• 37. Bower JE, Wiley J, Petersen L, Irwin MR, Cole SW, Ganz PA. Fatigue after breast cancer treatment: Biobehavioral predictors of fatigue trajectories. Heal Psychol. 2018;37(11):1025-1034. doi:10.1037/hea0000652
• 38. Hsiao F-H, Kuo W-H, Jow G-M, et al. The changes of quality of life and their correlations with psychosocial factors following surgery among women with breast cancer from the post-surgery to post-treatment survivorship. The Breast. 2019;44:59-65. doi:10.1016/j.breast.2018.12.011
• 39. Lovelace DL, McDaniel LR, Golden D. Long‐Term Effects of Breast Cancer Surgery, Treatment, and Survivor Care. J Midwifery Womens Health. 2019;64(6):713-724. doi:10.1111/jmwh.13012
• 40.Hassamal S, Razavi M, Clark K, Dale W, Loscalzo M. Pain distress among patients prior to initiating cancer treatment. Psychooncology. 2020;29(5):938-941. doi:10.1002/pon.5365
• 41.Wang K, Yee C, Tam S, et al. Prevalence of pain in patients with breast cancer post-treatment: A systematic review. The Breast. 2018;42:113-127. doi:10.1016/j.breast.2018.08.105
• 42.Langford DJ, Paul SM, Cooper B, et al. Comparison ofsubgroups of breast cancer patients on pain and co-occurring symptoms following chemotherapy. Support Care Cancer. 2016;24(2):605-614. doi:10.1007/s00520-015-2819-1
• 43.Arefian M, Asgari-Mobarake K, Fazilatpour M, Zanguri V, Akrami M. Proposing and evaluating a model of depression, stress, resilience and spirituality in relation to pain in womenwith breast cancer: Investigating the mediating role ofmindfulness. Eur J Oncol Nurs. 2023;62:102268. doi:10.1016/j.ejon.2023.102268
• 44.Lester J, Crosthwaite K, Stout R, et al. Women With BreastCancer: Self-Reported Distress in Early Survivorship. Oncol Nurs Forum. 2015;42(1):E17-E23. doi:10.1188/15.ONF.E17-E23
• 45.Liesto S, Sipilä R, Aho T, Harno H, Hietanen M, Kalso E. Psychological resilience associates with pain experience in women treated for breast cancer. Scand J Pain. 2020;20(3):545-553. doi:10.1515/sjpain-2019-0137
• 46.Smith TG, Troeschel AN, Castro KM, et al. Perceptions of Patients With Breast and Colon Cancer of the Management ofCancer-Related Pain, Fatigue, and Emotional Distress in Community Oncology. J Clin Oncol. 2019;37(19):1666-1676. doi:10.1200/JCO.18.01579